Carassius auratus (goldfish): 113067204
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Entry
113067204 CDS
T07313
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
caua
Carassius auratus (goldfish)
Brite
KEGG Orthology (KO) [BR:
caua00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
caua01001
]
113067204 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
caua04131
]
113067204 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
caua04147
]
113067204 (lrrk2)
Enzymes [BR:
caua01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113067204 (lrrk2)
Protein kinases [BR:
caua01001
]
Serine/threonine kinases: TKL group
LRRK family
113067204 (lrrk2)
Membrane trafficking [BR:
caua04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
113067204 (lrrk2)
Exosome [BR:
caua04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
113067204 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
COR
Roc
Ras
Ank_3
Ank_4
Ank
LRR_9
Ank_2
MMR_HSR1
Arf
Motif
Other DBs
NCBI-GeneID:
113067204
NCBI-ProteinID:
XP_026095302
Ensembl:
ENSCARG00000069416
UniProt:
A0A6P6MG04
LinkDB
All DBs
Position
50:complement(17472824..17511577)
Genome browser
AA seq
2527 aa
AA seq
DB search
MADKEELGIRLKKLLVRLNLQEGKQLGTMVQIMQDLLFLSHTEHCVELFADQNVHMPLIL
VLSSHFNNKVQQVGWSLLCRLMEICPDTLDSLANPDEYEFTEVHKQILKVLSVYRKDSKM
MMVGLRALALLLKSDAILMQILDEVEVDVFDLVLDAMRSFPDKEEVHLQGCAALQLLLQT
VSDAHLVEFIENKDHEVVLDALRLFMDSDNVVLQALRVLIPLSAPASNIEILMSKPVKCY
SLVCQAMDMWLDSEPIQEVGCRLLRKFTSESYYNILVLNGVHKVVVKACVSYPKNATVQT
TGLSCLSALAECIVQNVGLEEDEAKRKEATQGEEMLIWREACYTALERHADNPAVQETVC
WALNSLLLHYNSFNHVELEGRPPLHSLIMAAMLLHSSSVEVFQAASCTLLTLIQRHSRIR
ALLLSHGIHVNIVHLMQKHADSSAVCERACKLLHTLFQGARASLDDGTLMLGQILTALRT
HNFIPEVQLEGLRASLVLLSPDRSLREHGTSVADPDTVDVSLRVLKNQCVLEGAHTVYLQ
ALNRFISSEEIQECGLGVLSALTDCSGAVDLMCQQGAIDTVLHTLQMFPQEREVHYWGLS
LLFHLISKKKLSRMVVPVLASVLVSSVRQHKEDTVMLLKGLRAVWKLLDTCSSAAAWLQK
EAFEKEIFQILRESTTDQRRDPLQGMSCLCLSKMVADSEILYTLLDRACEDGDVDMAECL
IQLGADINKKTKSDSLIYQVCDRGAPLALLELLVSAGVHEQQLRGALSVCVRRGDDPAVT
LLLGRLGLDHANNALCLGSFRLGQMKALWLSALLSERKPQSPVNKKNSKGQRLAGQILSF
QRNKGFVGVGRLRSDASASEYFTDEESDESHISLDESLVSLFDDMEIDGSDGPSQGLLLF
NDSPEVGRKPAWRHPSWRGRANSEGCHGETDPSVPLNKHSHNTRGQGFMENSATGAFPLA
VDKEPIRLLDLSGNELGNLSCLIGASALKHQIESLLRLDLSSNSLSEFPCVLCQHLRSLK
RLDLQGNLLQSLPVELLGLPALSTLNVSRNCIGPLLLLDPTVCSPALRQLNLSFNQITVF
PFQLGQTMDRLEELLLEGNQISALSLPLSLAELKVLDISKNQVKIISENFLTECLKLETF
IASVNQISSLSHLPSKITTVKLSQNNFTSVPEIISNLPNLRSLDMRNNSISVLPGPALWV
SVNLRELMFSHNHISVLDLSGPVYKWARLEKLHLSSNKLTEIPPQIGMLEGLTSLDVSQN
EGLRSFPDEMGKLVHLWDLPLDGLQLQMDLKHIGNKTKDIIRFLQQRLKKAVPYYRMKLI
VVGSPCSGKSSLIHQLMKLKHSHWRSDQHTIGISVRDWAIRNKDKKKMLLNVWEFSGGEE
CSGFHPHFMSSRALYLVLYDPSKGPSEIDAIKPWLFNIKAIAGQSPVIVVGTHADVCEEH
HLQECVRKLREELSQPGFPVIKENHILCACEESESISRLRKALYRELIEFKIQGQPVMGQ
LIPDCYVELERRVLQERSHVPTDFPVLSHNRLLEIIQESQLQLEEGELPHAINFLSEAGV
LLHFDDPVLQLKDLYFIDPQWLSNIISQTLTLRSTGQWGSTTGVVQRTTVEKFLNKGRCF
PKNHLTQYFKLLEKFQIALPFGDDQLLIPSSLSDQKPVIELPHCENSEVIVRLYEMPYFP
MGYWSRQISHLLEVSAFLLYGKEKALRPNRIYWRKGIYLSWSAEAYCLVEALSLEDNPAS
LIKITVPCSLKGRVLFGQVVDHIDSLLEEWFPGLLVTDVHGTGETLLKKWAVYSFNDGQN
CQKMLLEDLLSKINADGLLVNPEDPSCTLPISQISPDLVLCDQASSTILDPEQLEMELSM
DYMLGDGGFGSVYKAVYKNEEVAVKIFNKHASTLYVHRLLRQELVVLGRLHHPSLVGLLA
AGCNPHILVMELAPCGSLDSLFEYENSRLSRKLQHRIALHVADGLRYLHSSMIIYRDLKP
HNVLLFNLKTDAEVIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVARGNVIYNVQADVY
SFGLLLYDLLTYGERISDGMKFPSEFDEVAVQGKLPDPVKNYGCSPWPGFESLMKDCLRE
NPQDRPTSAQVFVRLNSVEMLCLMRELTVMSLPGECFTVSSADGGADGGKNIRVWIGGGS
CSQKLGCVTSLQLETGGSLSQEIDSSPILCMVIIRAPGSCSDWLVAGTQSGSLFIMDTIN
AEVLHCLKSVKDSVTSLYFHTDLHHRYLKNYLLVGTADGSLVIYEDSVLKVKNGGPVKIL
QVGDVNTPVMCLGPSSHPQDRRGLWAACCSRVISLTVEYDIFRSIDTRPKQLFPQQDRIS
SDLCISRLAVDKHVYVSKRGGHTVEVWDKKTERMVNLIDCAQILGLSTAKKPRAHSEDQS
RQMVPSSAIVKALLVQHSGTLWIGTKAGHILLVEVSSCQLLQTISPHCHSLCCMASVLLD
TLNRKNVILVLGRRQRMAQDQIKTQVPAEDSVLTVWSSSLPLESRDLIRHCELRDKITSK
MRETLHN
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggctgataaagaggagctggggatcaggctcaagaagctgctggtgaggttgaacctt
caagaggggaagcagttgggcaccatggtccagattatgcaagacctgctgttcctgtcc
catacggagcactgtgttgagctgtttgctgatcaaaacgtccatatgcctctgattctg
gtattatcatcgcattttaacaacaaagttcagcaggtaggctggtctctgctctgtcgt
ctgatggagatctgtcccgacactctggacagtctggccaaccctgatgaatatgagttt
actgaggtgcacaagcagatcttaaaagtgctttcagtgtatcgtaaagattccaaaatg
atgatggtgggcctgagagctctggctctcctactgaaatcagatgcgattctgatgcag
attctggacgaggtagaggtggacgtttttgacttggttctggacgccatgaggtcattt
cctgacaaagaagaggttcatctacagggatgtgctgctttacaactactgctgcaaact
gtttctgatgctcacctggtggagttcattgagaacaaggaccatgaggtggttttggac
gcgcttaggctgttcatggacagtgacaatgtggttctgcaagctctaagggtcctcata
ccactgtctgctccagccagcaatattgagattctgatgtccaaacccgttaaatgctac
agtctagtgtgtcaggctatggacatgtggctcgactcggagcccatacaggaggttggg
tgccgtctgttacggaaatttacttcagagagttactataacatactggtgctgaatggt
gtccataaggtggtggtgaaagcatgtgtctcttatcctaagaatgccacagtgcagacc
actggcctttcctgcctgagcgcactcgccgagtgtattgtacagaatgtagggctggag
gaggacgaggcaaaacggaaagaagccacccaaggagaggaaatgcttatctggagagag
gcctgttatactgctttagagagacatgctgacaatcctgcagtgcaggaaactgtatgt
tgggctttaaacagcttgctgcttcattacaactccttcaaccatgtggaactggaagga
agacctccccttcattctctcatcatggccgccatgcttttgcattcatccagtgtggag
gttttccaagctgcttcctgtacactactcacactaatacagcgccacagtcggataagg
gctctgctgctgtcacatggcattcatgtcaacattgtgcatctgatgcagaaacacgca
gactccagcgccgtgtgtgaaagagcctgcaaactgcttcacacactcttccagggagcg
cgggccagtctagatgacgggaccctgatgctcggtcagatcctgactgctctcaggaca
cataacttcattcctgaggttcagctggagggtctcagagccagtttagttctcctcagt
ccagacaggagtttaagagagcatggcacctcggtggcggaccctgacacggtggacgtg
tccctgcgagtgctgaagaaccagtgtgtactagagggagctcacactgtctatctacag
gcacttaataggtttatcagtagtgaggagattcaggagtgtggactcggtgtgctctcg
gcgctaactgactgttctggagccgttgacctcatgtgccagcagggagcgatagatacg
gttcttcatacgctgcagatgtttccacaggagcgcgaagttcactactggggccttagt
cttctgtttcacctcatctctaagaagaagctctctcgtatggtggtgcctgtactggcc
tcagttttggtcagctctgtacggcaacacaaagaggacactgtcatgcttctaaagggt
cttcgggcggtgtggaagttgttggatacctgctcgagtgccgcagcgtggctgcagaag
gaagccttcgagaaagaaatcttccagatcctgcgggaaagtacaacagaccagcgccga
gatccactgcagggaatgagttgcctgtgcctgtctaagatggtggcggacagtgagatc
ctgtacacgctgctggacagagcgtgtgaggacggtgatgtggacatggcagaatgtctc
atccagctgggtgctgacatcaacaagaaaacaaagagcgattcacttatatatcaggtt
tgtgatcgaggggctcctctggcactgctggagctgctggtttctgcaggagttcatgag
cagcagttacgtggagctctgagcgtgtgtgtcaggaggggtgatgaccctgccgtcacc
ctcttgctcggccgtctggggctggaccacgccaacaatgccctgtgcctcgggagcttc
cgcctcggacaaatgaaagcgttgtggcttagcgctctgctctcggagcgcaaacctcag
tctcctgtcaacaagaagaacagtaaaggtcagcgtttagccggacagatcttgtcattc
cagaggaataaagggtttgtgggagttggtagattacggagtgatgccagcgcatcagaa
tatttcacagatgaggaaagtgacgaatcacacatttccttagatgaaagtctggtctca
ttgtttgatgacatggagattgacgggagtgacgggccttcacaaggattgttgcttttc
aacgattctccagaagtgggcaggaaacctgcttggagacatcccagctggcgtggacgt
gccaattcagagggatgccacggtgagacggatccaagcgtccctctaaataagcactct
cacaacactagagggcagggtttcatggaaaactccgctactggtgcttttcctctggcc
gtagacaaagagcccatccgtctgctggacctctcagggaatgagctgggcaatctgtcc
tgtctgattggtgcaagcgctctcaaacaccagattgaaagccttcttcggcttgatttg
agcagcaacagtctatcagagtttccctgtgttctctgtcagcatttaagaagtcttaag
cgtctagatcttcaaggtaacctcctgcagtcacttcctgtggagcttctgggtttacct
gcactgagcacgctcaatgtttctcgcaactgcattggtcctcttctgctgctggaccca
actgtgtgcagtccagccttacgccagctcaacctttccttcaaccagatcaccgtcttc
cccttccagctggggcagaccatggacagactggaggagctcttattggagggcaatcag
atatcagcactgtctctcccactcagcctggctgaattgaaagttttagacatcagtaag
aatcaagtaaaaatcatttcagaaaacttcctcactgaatgtctcaagttggaaactttc
atcgcttcagttaaccaaatcagttcattgtcacaccttccctcaaaaataaccactgtt
aaactatcacaaaacaatttcacaagtgttcctgaaataatcagcaacttgccaaatttg
cgttcattggacatgagaaataacagtattagtgttttgccgggaccggctttgtgggtc
agtgtaaacctaagagagctgatgttcagtcataatcacatctctgtgctcgacctgagc
ggcccggtgtacaagtgggccagactggaaaaacttcatttgagctctaacaaactcact
gagatccctcctcagatcggtatgttggagggcctgacatctcttgatgtcagtcagaat
gaaggtttgcgctctttccctgatgagatgggaaagctggttcatttatgggatctacct
ctagatggtctgcagctccagatggacctcaagcacatagggaacaaaaccaaagacatc
atcagattcttgcagcagcgcctgaagaaagctgtaccatattaccgcatgaaactcatt
gtggtcggcagcccatgtagcgggaaaagttctttgattcatcagctgatgaagctcaaa
cattctcattggcgatctgatcagcacaccatcggcatcagcgttagagactgggccatc
agaaacaaagacaagaagaaaatgctcctgaatgtttgggagttctcaggtggtgaagag
tgcagtggatttcaccctcactttatgagctccagggcactctatctagtgctgtatgac
ccgagtaaaggacccagtgagatagacgccatcaaaccctggctctttaacattaaagcc
atagctggacagtcccctgtgattgtggttggaactcatgcagatgtgtgtgaagaacac
cacctacaggagtgtgttcggaagctgcgagaggagctgtctcaaccgggctttccagtg
atcaaagagaaccacatactatgtgcctgcgaggagtcggagtccatcagcaggttgcgc
aaagccttgtatagagagctcattgagttcaagatccagggtcagccggtaatggggcag
ctgattccagactgctatgtggagttggagaggagagttttacaggagaggtcacatgta
cccactgatttcccagtgctcagtcacaacagactactggagattatacaggaatcacag
ctgcagctagaggagggagaattaccacatgccattaacttcctcagtgaggctggtgtc
ctgctgcattttgatgatccagtgcttcagctaaaggatttgtacttcattgacccacaa
tggctatctaacatcatatcacagacgctcactctaaggagcactggtcagtggggcagc
accacaggagtggtgcagcgaactactgtagaaaagtttctaaacaaaggtcgctgtttc
ccaaaaaatcatctgactcagtacttcaaactattggaaaagtttcaaatagctcttccc
tttggagatgaccagttacttatacctagcagcctatcagatcaaaagccggtgattgag
ctccctcactgtgagaattcagaggtgatagttcggctttatgagatgccatacttcccc
atgggctactggtccagacagatcagccatctgttggaagtgtctgcattcctgctctac
ggcaaagaaaaagcattgagaccaaacaggatctactggaggaagggcatatatctgagc
tggtctgctgaagcttactgtctggtggaggcattgtctctagaagacaacccagctagc
ttgatcaagatcactgtcccctgctctctgaaaggtcgtgtgttgtttgggcaggtggtg
gatcacattgactctctgttggaagaatggtttccaggcctcctcgtcactgatgtccat
ggcaccggagagacactgcttaagaaatgggctgtgtacagcttcaatgatggacaaaac
tgccaaaagatgctgctggaagatcttctctccaaaatcaatgcagatggtttgctggtg
aacccagaagaccccagctgtactctgcccatatctcagatctctccagacctggtactg
tgtgatcaggcgtccagcaccatattggatccagagcaactggagatggagctctcaatg
gactatatgttgggagatggaggctttggctctgtatataaagctgtgtacaagaatgag
gaagttgctgtgaagattttcaataaacatgcatctacactttatgttcatcggctgcta
cgacaggaactggtcgttcttggcagactgcatcaccccagtctggtggggcttttggct
gctggatgtaacccgcacattcttgtgatggaactcgccccatgtggctctctagactca
ctttttgagtatgaaaacagccgcctcagccgcaaactacagcacaggatagcactgcat
gtggcagatggtctcagatatttgcactcttctatgattatctaccgagatctgaagccg
cacaatgttctgttgtttaacctgaagacggatgctgaggtcattgctaaaatcacagac
tatggcatagcgcagtactgttgcagtatgggtgtccgcagctcagaaggaacaccaggt
tttagagccccggaggtcgcccgaggtaatgtcatctataacgtccaggcagatgtatat
tcgtttggtctgctgctgtatgaccttttgacttacggtgagaggatatccgatggaatg
aagtttcctagtgagtttgatgaggtggctgtgcagggaaaactaccagatccagttaaa
aattatggatgttctccatggccagggtttgagtctttgatgaaggactgtttgagagaa
aacccacaggacaggcctacatctgctcaggtctttgttcgtctgaattctgtagagatg
ctttgtctgatgcgagagctgactgtgatgagtttgccgggtgagtgtttcactgtctcc
agtgccgatggaggtgcagacggaggtaaaaatatccgtgtgtggattggaggtggcagt
tgcagccagaaattaggctgtgtgacatcactgcaactggagacagggggaagcttgagc
caggagattgacagcagtcctatcctctgcatggtgatcatcagagctccagggtcatgc
agtgactggttagttgctgggacacagtcaggttcactctttatcatggacactataaac
gcagaggttctgcactgtctgaagagtgtgaaggactccgtgacatcactctactttcac
actgaccttcatcacagatacttaaagaattaccttttggtcgggacagcagatggatca
ctggtcatttatgaagattcagtcttgaaggtgaagaatggtggtccagtgaaaatactg
caggttggtgatgtgaacactcctgtgatgtgtctcggtccgtccagtcaccctcaggac
cgcagaggtctgtgggcggcctgttgcagcagggtgatctcgctcacagtggaatatgac
atcttcaggagcatagacaccagacccaaacagctgttcccgcaacaggatcgaatcagc
agtgatctttgtatatcacggttagcggtggacaaacatgtgtatgtaagtaaaaggggc
ggccacactgtggaggtctgggataagaagactgagaggatggtgaacctcattgactgc
gcacagatacttggattaagtaccgccaaaaagcccagagcacatagtgaggaccagtct
agacaaatggtgccatcttcggcgattgttaaagctctgttggtccagcacagtggtact
ctgtggatcgggaccaaagcaggacacatcctgttggtggaagtctccagctgtcagcta
cttcagaccatcagccctcactgccactccttatgctgcatggcctcggtgctgttagac
acactaaaccgaaagaatgttattctagtattgggtagacggcaacgaatggcacaagac
caaatcaaaacacaagtcccagctgaggattcagtgctgacggtgtggagcagctcactt
cctctggagagccgagatctgatcagacactgtgaactacgagacaagatcaccagcaaa
atgagagaaacactccacaactga
DBGET
integrated database retrieval system
