Castor canadensis (American beaver): 109681514
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Entry
109681514 CDS
T04791
Symbol
Chuk
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
KO
K04467
inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:
2.7.11.10
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan01523
Antifolate resistance
ccan04010
MAPK signaling pathway
ccan04014
Ras signaling pathway
ccan04062
Chemokine signaling pathway
ccan04064
NF-kappa B signaling pathway
ccan04068
FoxO signaling pathway
ccan04150
mTOR signaling pathway
ccan04151
PI3K-Akt signaling pathway
ccan04210
Apoptosis
ccan04380
Osteoclast differentiation
ccan04620
Toll-like receptor signaling pathway
ccan04621
NOD-like receptor signaling pathway
ccan04622
RIG-I-like receptor signaling pathway
ccan04623
Cytosolic DNA-sensing pathway
ccan04625
C-type lectin receptor signaling pathway
ccan04657
IL-17 signaling pathway
ccan04658
Th1 and Th2 cell differentiation
ccan04659
Th17 cell differentiation
ccan04660
T cell receptor signaling pathway
ccan04662
B cell receptor signaling pathway
ccan04668
TNF signaling pathway
ccan04920
Adipocytokine signaling pathway
ccan04936
Alcoholic liver disease
ccan05010
Alzheimer disease
ccan05132
Salmonella infection
ccan05135
Yersinia infection
ccan05142
Chagas disease
ccan05145
Toxoplasmosis
ccan05160
Hepatitis C
ccan05161
Hepatitis B
ccan05162
Measles
ccan05163
Human cytomegalovirus infection
ccan05164
Influenza A
ccan05165
Human papillomavirus infection
ccan05166
Human T-cell leukemia virus 1 infection
ccan05167
Kaposi sarcoma-associated herpesvirus infection
ccan05168
Herpes simplex virus 1 infection
ccan05169
Epstein-Barr virus infection
ccan05170
Human immunodeficiency virus 1 infection
ccan05171
Coronavirus disease - COVID-19
ccan05200
Pathways in cancer
ccan05208
Chemical carcinogenesis - reactive oxygen species
ccan05212
Pancreatic cancer
ccan05215
Prostate cancer
ccan05220
Chronic myeloid leukemia
ccan05221
Acute myeloid leukemia
ccan05222
Small cell lung cancer
ccan05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05417
Lipid and atherosclerosis
ccan05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109681514 (Chuk)
04014 Ras signaling pathway
109681514 (Chuk)
04064 NF-kappa B signaling pathway
109681514 (Chuk)
04668 TNF signaling pathway
109681514 (Chuk)
04068 FoxO signaling pathway
109681514 (Chuk)
04151 PI3K-Akt signaling pathway
109681514 (Chuk)
04150 mTOR signaling pathway
109681514 (Chuk)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
109681514 (Chuk)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
109681514 (Chuk)
04621 NOD-like receptor signaling pathway
109681514 (Chuk)
04622 RIG-I-like receptor signaling pathway
109681514 (Chuk)
04623 Cytosolic DNA-sensing pathway
109681514 (Chuk)
04625 C-type lectin receptor signaling pathway
109681514 (Chuk)
04660 T cell receptor signaling pathway
109681514 (Chuk)
04658 Th1 and Th2 cell differentiation
109681514 (Chuk)
04659 Th17 cell differentiation
109681514 (Chuk)
04657 IL-17 signaling pathway
109681514 (Chuk)
04662 B cell receptor signaling pathway
109681514 (Chuk)
04062 Chemokine signaling pathway
109681514 (Chuk)
09152 Endocrine system
04920 Adipocytokine signaling pathway
109681514 (Chuk)
09158 Development and regeneration
04380 Osteoclast differentiation
109681514 (Chuk)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109681514 (Chuk)
05208 Chemical carcinogenesis - reactive oxygen species
109681514 (Chuk)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
109681514 (Chuk)
09162 Cancer: specific types
05212 Pancreatic cancer
109681514 (Chuk)
05221 Acute myeloid leukemia
109681514 (Chuk)
05220 Chronic myeloid leukemia
109681514 (Chuk)
05215 Prostate cancer
109681514 (Chuk)
05222 Small cell lung cancer
109681514 (Chuk)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
109681514 (Chuk)
05170 Human immunodeficiency virus 1 infection
109681514 (Chuk)
05161 Hepatitis B
109681514 (Chuk)
05160 Hepatitis C
109681514 (Chuk)
05171 Coronavirus disease - COVID-19
109681514 (Chuk)
05164 Influenza A
109681514 (Chuk)
05162 Measles
109681514 (Chuk)
05168 Herpes simplex virus 1 infection
109681514 (Chuk)
05163 Human cytomegalovirus infection
109681514 (Chuk)
05167 Kaposi sarcoma-associated herpesvirus infection
109681514 (Chuk)
05169 Epstein-Barr virus infection
109681514 (Chuk)
05165 Human papillomavirus infection
109681514 (Chuk)
09171 Infectious disease: bacterial
05132 Salmonella infection
109681514 (Chuk)
05135 Yersinia infection
109681514 (Chuk)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
109681514 (Chuk)
05142 Chagas disease
109681514 (Chuk)
09164 Neurodegenerative disease
05010 Alzheimer disease
109681514 (Chuk)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109681514 (Chuk)
05418 Fluid shear stress and atherosclerosis
109681514 (Chuk)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109681514 (Chuk)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109681514 (Chuk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccan01001
]
109681514 (Chuk)
Enzymes [BR:
ccan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
109681514 (Chuk)
Protein kinases [BR:
ccan01001
]
Serine/threonine kinases: Other
IKK family [OT]
109681514 (Chuk)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
IKKbetaNEMObind
Pkinase_fungal
Kdo
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
109681514
NCBI-ProteinID:
XP_020011900
UniProt:
A0A250YL28
LinkDB
All DBs
Position
Unknown
AA seq
745 aa
AA seq
DB search
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELELKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDPTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPSDESLHSLQSRIERETGINTGSQELLSETGI
SLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPI
VQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKL
EFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIRYAEVGVIGYLEDQIMSLHTE
IMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPADHSYSDSTEMVKIIVHTVQSQDRV
LKELFGHLSKLLGCKQKIIDLLPKVEIALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQ
SSARSLVGSSLEGAVTPHASAWLPPTLAECEHPLSCVVTPQDGETLPQMIEENLNCLGHL
STIIREANEEQGSSMMNLDWSWLAE
NT seq
2238 nt
NT seq
+upstream
nt +downstream
nt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
cttggcaccggaggattcggaaatgtctgtctgtaccagcatcgggaacttgaactcaaa
atagcaattaagtcttgtcgcctggagttaagtaccaaaaatagagaacgatggtgccac
gaaatccagatcatgaagaagttgaaccatgccaatgttgtaaaggcctgtgatgttcct
gaggaactgaattttttgattaatgatgtacctcttctggcaatggaatactgttctgga
ggagatctccggaagctactcaacaaaccagaaaattgttgtggacttaaagaaagccag
atactttctttgctgagtgatataggatctgggattcgatatttgcatgaaaataaaatt
atacatcgagatctaaaacctgaaaatatagttctacaggatgttggtggaaagataatg
cataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctctgtacatct
tttgtgggaacactgcagtatctggccccagagctctttgagaataagccttacacagct
actgttgattattggagctttgggaccatggtatttgaatgtattgccggatatagacct
tttttacatcatctgcagccatttacctggcatgagaagattaagaagaaggatcctaag
tgtatatttgcgtgtgaagagatgacaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctacagctgatgctg
aattgggacccacagcaaagagggggccctgttgaccctactttgaagcagccaagatgc
tttgtattaatggatcacattctgaatttaaagatagtgcacatcctaaatatgacttct
gcaaagataatttcttttctgttaccatctgatgaaagtcttcattcactacagtctcgt
attgagcgtgaaactggaataaatactggttctcaagaactgctttcagagacaggaatt
tctctggatcctcggaaaccagcctctcagtgtgttctagatggagttagaggctgtgat
agttacatggtttacttgtttgataaaagcaagactgtatatgaagggccatttgcttcc
agaagtttatctgattgtgtaaattatattgtacaagacagcaaaatacagcttccaatt
gtacagttacgtaaagtatgggctgaggcagtacactacgtgtctggactaaaagaagac
tacagcaggctgtttcagggacaaagagcagcaatgttaagtcttcttagatataatgct
aacttgacaaaaatgaagaatactttgatatcagcatcacagcaactgaaagctaaactg
gagttttttcacaaaagcattcaacttgacttggagagatacagtgaacaaatgacttat
gggatatcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccgc
tatgctgaggttggtgtcattggatacctagaggatcagattatgtctttacacactgaa
atcatggaactacagaagagcccttatggaagacgtcagggagacttgatggaatctctg
gagcaacgtgccattgatctttataagcagttaaagcacagacctgcagatcattcctac
agtgacagcacagagatggtgaagatcattgtgcatactgtacagagtcaggaccgtgtt
ctcaaggagctgtttggtcatctgagcaagttgttgggctgtaagcagaagattattgat
ctactccccaaagtggaaatcgccctcagtaacatcaaagaagctgacaatactgtcatg
tttatgcagggaaagaggcagaaagaaatatggcatctccttaaaattgcctgtacacag
agttctgcccgctcccttgtggggtccagtctagaaggtgcagtaacccctcacgcatca
gcatggctacccccgaccttagcagaatgtgaacaccctctgtcatgcgtggtaactcct
caagatggggaaactttaccacaaatgatagaagaaaatttgaactgtctcggccattta
agtactattattcgtgaagcaaatgaggaacagggcagtagcatgatgaatcttgattgg
agttggttagcagaatga
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integrated database retrieval system