KEGG   Castor canadensis (American beaver): 109687060
Entry
109687060         CDS       T04791                                 
Symbol
Kras
Name
(RefSeq) GTPase KRas
  KO
K07827  GTPase KRas
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan01522  Endocrine resistance
ccan04010  MAPK signaling pathway
ccan04012  ErbB signaling pathway
ccan04014  Ras signaling pathway
ccan04015  Rap1 signaling pathway
ccan04062  Chemokine signaling pathway
ccan04068  FoxO signaling pathway
ccan04071  Sphingolipid signaling pathway
ccan04072  Phospholipase D signaling pathway
ccan04137  Mitophagy - animal
ccan04140  Autophagy - animal
ccan04150  mTOR signaling pathway
ccan04151  PI3K-Akt signaling pathway
ccan04210  Apoptosis
ccan04211  Longevity regulating pathway
ccan04213  Longevity regulating pathway - multiple species
ccan04218  Cellular senescence
ccan04360  Axon guidance
ccan04370  VEGF signaling pathway
ccan04371  Apelin signaling pathway
ccan04540  Gap junction
ccan04550  Signaling pathways regulating pluripotency of stem cells
ccan04625  C-type lectin receptor signaling pathway
ccan04650  Natural killer cell mediated cytotoxicity
ccan04660  T cell receptor signaling pathway
ccan04662  B cell receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04714  Thermogenesis
ccan04720  Long-term potentiation
ccan04722  Neurotrophin signaling pathway
ccan04725  Cholinergic synapse
ccan04726  Serotonergic synapse
ccan04730  Long-term depression
ccan04810  Regulation of actin cytoskeleton
ccan04910  Insulin signaling pathway
ccan04912  GnRH signaling pathway
ccan04914  Progesterone-mediated oocyte maturation
ccan04915  Estrogen signaling pathway
ccan04916  Melanogenesis
ccan04917  Prolactin signaling pathway
ccan04919  Thyroid hormone signaling pathway
ccan04921  Oxytocin signaling pathway
ccan04926  Relaxin signaling pathway
ccan04929  GnRH secretion
ccan04933  AGE-RAGE signaling pathway in diabetic complications
ccan04935  Growth hormone synthesis, secretion and action
ccan04960  Aldosterone-regulated sodium reabsorption
ccan05010  Alzheimer disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05034  Alcoholism
ccan05160  Hepatitis C
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05165  Human papillomavirus infection
ccan05166  Human T-cell leukemia virus 1 infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05200  Pathways in cancer
ccan05203  Viral carcinogenesis
ccan05205  Proteoglycans in cancer
ccan05206  MicroRNAs in cancer
ccan05207  Chemical carcinogenesis - receptor activation
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05210  Colorectal cancer
ccan05211  Renal cell carcinoma
ccan05212  Pancreatic cancer
ccan05213  Endometrial cancer
ccan05214  Glioma
ccan05215  Prostate cancer
ccan05216  Thyroid cancer
ccan05218  Melanoma
ccan05219  Bladder cancer
ccan05220  Chronic myeloid leukemia
ccan05221  Acute myeloid leukemia
ccan05223  Non-small cell lung cancer
ccan05224  Breast cancer
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
ccan05230  Central carbon metabolism in cancer
ccan05231  Choline metabolism in cancer
ccan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109687060 (Kras)
   04012 ErbB signaling pathway
    109687060 (Kras)
   04014 Ras signaling pathway
    109687060 (Kras)
   04015 Rap1 signaling pathway
    109687060 (Kras)
   04370 VEGF signaling pathway
    109687060 (Kras)
   04371 Apelin signaling pathway
    109687060 (Kras)
   04068 FoxO signaling pathway
    109687060 (Kras)
   04072 Phospholipase D signaling pathway
    109687060 (Kras)
   04071 Sphingolipid signaling pathway
    109687060 (Kras)
   04151 PI3K-Akt signaling pathway
    109687060 (Kras)
   04150 mTOR signaling pathway
    109687060 (Kras)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    109687060 (Kras)
   04137 Mitophagy - animal
    109687060 (Kras)
  09143 Cell growth and death
   04210 Apoptosis
    109687060 (Kras)
   04218 Cellular senescence
    109687060 (Kras)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    109687060 (Kras)
   04550 Signaling pathways regulating pluripotency of stem cells
    109687060 (Kras)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109687060 (Kras)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    109687060 (Kras)
   04650 Natural killer cell mediated cytotoxicity
    109687060 (Kras)
   04660 T cell receptor signaling pathway
    109687060 (Kras)
   04662 B cell receptor signaling pathway
    109687060 (Kras)
   04664 Fc epsilon RI signaling pathway
    109687060 (Kras)
   04062 Chemokine signaling pathway
    109687060 (Kras)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109687060 (Kras)
   04929 GnRH secretion
    109687060 (Kras)
   04912 GnRH signaling pathway
    109687060 (Kras)
   04915 Estrogen signaling pathway
    109687060 (Kras)
   04914 Progesterone-mediated oocyte maturation
    109687060 (Kras)
   04917 Prolactin signaling pathway
    109687060 (Kras)
   04921 Oxytocin signaling pathway
    109687060 (Kras)
   04926 Relaxin signaling pathway
    109687060 (Kras)
   04935 Growth hormone synthesis, secretion and action
    109687060 (Kras)
   04919 Thyroid hormone signaling pathway
    109687060 (Kras)
   04916 Melanogenesis
    109687060 (Kras)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    109687060 (Kras)
  09156 Nervous system
   04725 Cholinergic synapse
    109687060 (Kras)
   04726 Serotonergic synapse
    109687060 (Kras)
   04720 Long-term potentiation
    109687060 (Kras)
   04730 Long-term depression
    109687060 (Kras)
   04722 Neurotrophin signaling pathway
    109687060 (Kras)
  09158 Development and regeneration
   04360 Axon guidance
    109687060 (Kras)
  09149 Aging
   04211 Longevity regulating pathway
    109687060 (Kras)
   04213 Longevity regulating pathway - multiple species
    109687060 (Kras)
  09159 Environmental adaptation
   04714 Thermogenesis
    109687060 (Kras)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109687060 (Kras)
   05206 MicroRNAs in cancer
    109687060 (Kras)
   05205 Proteoglycans in cancer
    109687060 (Kras)
   05207 Chemical carcinogenesis - receptor activation
    109687060 (Kras)
   05208 Chemical carcinogenesis - reactive oxygen species
    109687060 (Kras)
   05203 Viral carcinogenesis
    109687060 (Kras)
   05230 Central carbon metabolism in cancer
    109687060 (Kras)
   05231 Choline metabolism in cancer
    109687060 (Kras)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109687060 (Kras)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109687060 (Kras)
   05212 Pancreatic cancer
    109687060 (Kras)
   05225 Hepatocellular carcinoma
    109687060 (Kras)
   05226 Gastric cancer
    109687060 (Kras)
   05214 Glioma
    109687060 (Kras)
   05216 Thyroid cancer
    109687060 (Kras)
   05221 Acute myeloid leukemia
    109687060 (Kras)
   05220 Chronic myeloid leukemia
    109687060 (Kras)
   05218 Melanoma
    109687060 (Kras)
   05211 Renal cell carcinoma
    109687060 (Kras)
   05219 Bladder cancer
    109687060 (Kras)
   05215 Prostate cancer
    109687060 (Kras)
   05213 Endometrial cancer
    109687060 (Kras)
   05224 Breast cancer
    109687060 (Kras)
   05223 Non-small cell lung cancer
    109687060 (Kras)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109687060 (Kras)
   05170 Human immunodeficiency virus 1 infection
    109687060 (Kras)
   05161 Hepatitis B
    109687060 (Kras)
   05160 Hepatitis C
    109687060 (Kras)
   05163 Human cytomegalovirus infection
    109687060 (Kras)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109687060 (Kras)
   05165 Human papillomavirus infection
    109687060 (Kras)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109687060 (Kras)
   05022 Pathways of neurodegeneration - multiple diseases
    109687060 (Kras)
  09165 Substance dependence
   05034 Alcoholism
    109687060 (Kras)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109687060 (Kras)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    109687060 (Kras)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109687060 (Kras)
   01522 Endocrine resistance
    109687060 (Kras)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109687060 (Kras)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:ccan04031]
    109687060 (Kras)
Membrane trafficking [BR:ccan04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    109687060 (Kras)
GTP-binding proteins [BR:ccan04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    109687060 (Kras)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase MeaB FeoB_N ATP_bind_1 Septin G1_gp67_C NPR1_interact
Other DBs
NCBI-GeneID: 109687060
NCBI-ProteinID: XP_020020308
UniProt: A0A250XVZ2
LinkDB
Position
Unknown
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCVIM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaaccactttgtggatgagtacgaccctacgatagaggactcctac
aggaaacaagtagtcattgatggagagacctgtctcttggacattctcgacacagcaggt
caagaggagtacagtgcgatgagggaccagtacatgaggactggggagggctttctctgt
gtgtttgccataaataacactaagtcatttgaagacattcaccattatagagaacaaatt
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaaaatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtgtaattatgtaa

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