Castor canadensis (American beaver): 109688078 Help Entry 109688078         CDS       T04791                                  Symbol Syk Name (RefSeq) tyrosine-protein kinase SYK   KO K05855   spleen tyrosine kinase [EC:2.7.10.2] Organism ccan  Castor canadensis (American beaver) Pathway ccan04064   NF-kappa B signaling pathway ccan04072   Phospholipase D signaling pathway ccan04151   PI3K-Akt signaling pathway ccan04380   Osteoclast differentiation ccan04611   Platelet activation ccan04613   Neutrophil extracellular trap formation ccan04625   C-type lectin receptor signaling pathway ccan04650   Natural killer cell mediated cytotoxicity ccan04662   B cell receptor signaling pathway ccan04664   Fc epsilon RI signaling pathway ccan04666   Fc gamma R-mediated phagocytosis ccan05152   Tuberculosis ccan05167   Kaposi sarcoma-associated herpesvirus infection ccan05168   Herpes simplex virus 1 infection ccan05169   Epstein-Barr virus infection ccan05171   Coronavirus disease - COVID-19 ccan05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     109688078 (Syk)    04072 Phospholipase D signaling pathway     109688078 (Syk)    04151 PI3K-Akt signaling pathway     109688078 (Syk)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109688078 (Syk)    04613 Neutrophil extracellular trap formation     109688078 (Syk)    04625 C-type lectin receptor signaling pathway     109688078 (Syk)    04650 Natural killer cell mediated cytotoxicity     109688078 (Syk)    04662 B cell receptor signaling pathway     109688078 (Syk)    04664 Fc epsilon RI signaling pathway     109688078 (Syk)    04666 Fc gamma R-mediated phagocytosis     109688078 (Syk)   09158 Development and regeneration    04380 Osteoclast differentiation     109688078 (Syk)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     109688078 (Syk)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     109688078 (Syk)    05168 Herpes simplex virus 1 infection     109688078 (Syk)    05167 Kaposi sarcoma-associated herpesvirus infection     109688078 (Syk)    05169 Epstein-Barr virus infection     109688078 (Syk)   09171 Infectious disease: bacterial    05152 Tuberculosis     109688078 (Syk)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccan01001]     109688078 (Syk) Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      109688078 (Syk) Protein kinases [BR:ccan01001]  Non-receptor tyrosine kinases   SYK family    109688078 (Syk) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1 RIO1 Motif Other DBs NCBI-GeneID:  109688078 NCBI-ProteinID:  XP_020021918 UniProt:  A0A250YKH5 LinkDB All DBs Position Unknown AA seq 632 aa AA seqDB search MAGNVADSANHLPFFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHSRKA HHYTIEREINGTYAIPGGRTHSSPADLCHYHSQESDGLVCLLIKPFNRPPGVQPKTGPFE DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHETMPWFHGNISRDESEQI VLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV EHYSYKPDGLLRVLTVPCQKIGSQMGHPQSSSPSSGGWSPGGIISRIKSYSFARPGHKKT PPSQGNRQDRPESTASFNPYEPDRGPWPAERGPQREALPMDTEVYESPYADPEEIRPKEV YLDRNLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPTLKDELLAEANV MQQLDNPYIVRMIGICDAESWMLVMEMAELGSLNKYLQQNRHIKDKNIIELVHQVSMGMK YLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPEC INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYE LMNLCWTYEVENRPGFVAVELRLRNYYYDVVN NT seq 1899 nt NT seq  +upstreamnt  +downstreamnt atggcaggcaacgtggcggacagcgccaaccacctgcccttcttttttggcaacatcacc cgagaggaggcagaagactacctggtccaggggggcatgaccgatggactctacctgtta cgccagagtcgtaattacctgggtggctttgccctgtcagtggcccacagcaggaaggca caccactacaccatcgagagggagatcaatggcacctatgccatccctggtggcaggacc cacagcagccctgctgacctctgccactaccactcccaggagtccgacggcctggtctgc ctcctcataaagcccttcaaccggccccctggggtgcagcccaagactgggccatttgag gacctgaaggaaaacctcatcagggagtacgtgaagcagacgtggaacctgcagggccag gctttggaacaagccatcattagccagaagccccagctggagaagttgatcgccaccact gcccatgaaacaatgccatggttccatggcaatatctctcgggatgaatcagagcagatt gtcctgataggatcaaagacaaatggaaagtttctgatcagggccagagacaacaatggc tcctatgcactgtgcctgctgcacgaagggaaggtgctgcactaccgcatcgacaaggac aagacagggaagctctccatccctgagggaaagaagtttgacacactctggcagctggtg gaacattattcttataaacctgatggcctgttaagagttcttactgtgccatgtcaaaag attggctcacagatgggtcatccgcaaagttcaagtccctcctctgggggttggtctcca ggtggcataatctcaaggatcaaatcctactcctttgcaaggcctggccacaaaaagacc cccccgtcccaagggaaccggcaagaccggccagagagtactgcatccttcaatccctat gagccagaccgaggaccctggcctgcagagagaggccctcagagagaagctctgcccatg gatacagaggtgtatgaaagcccctatgctgaccctgaggaaatcaggcccaaagaggtc tacctggaccgaaacctgctgaccctggaggacaaagaactgggctctggtaactttgga accgtgaaaaagggctattaccaaatgaaaaaagttgtgaaaacggtggctgtgaaaata ctgaaaaacgaggccaacgaccccactctgaaagacgagctgctggcggaggcgaacgtc atgcagcagctggacaacccctacatcgtgcgcatgattgggatttgcgacgccgagtcc tggatgctggtgatggagatggcagaactcggttctctcaacaagtatttgcagcagaac aggcacatcaaggataagaacatcatagagctggttcatcaggtttccatgggaatgaaa tacttggaggagtgcaatttcgtgcacagagatctggctgcaagaaatgtattgctggtc actcagcattatgccaagatcagtgattttggtctttccaaagcgcttcgtgctgacgaa aactactataaggcgcagacccacgggaagtggccggtgaagtggtatgcccccgaatgc atcaactactacaaattctccagcaagagtgatgtctggagcttcggagtgctcatgtgg gaagcattttcctatgggcagaagccgtatcgagggatgaaaggaagtgaggttactgcc atgctggagaagggagagcggatggggtgtccaccagggtgcccaagagaaatgtatgag ctgatgaacctgtgctggacctatgaggtggagaacaggcctggatttgtagcggtggag ctgcggctgcgcaattattactacgacgtggtgaactag

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