Castor canadensis (American beaver): 109703069
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Entry
109703069 CDS
T04791
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00010
Glycolysis / Gluconeogenesis
ccan00020
Citrate cycle (TCA cycle)
ccan00620
Pyruvate metabolism
ccan00785
Lipoic acid metabolism
ccan01100
Metabolic pathways
ccan01200
Carbon metabolism
ccan01210
2-Oxocarboxylic acid metabolism
ccan04066
HIF-1 signaling pathway
ccan04922
Glucagon signaling pathway
ccan05230
Central carbon metabolism in cancer
ccan05415
Diabetic cardiomyopathy
Module
ccan_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
109703069
00020 Citrate cycle (TCA cycle)
109703069
00620 Pyruvate metabolism
109703069
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
109703069
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
109703069
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109703069
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
109703069
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109703069
Enzymes [BR:
ccan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
109703069
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Paralog
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
DUF2776
Motif
Other DBs
NCBI-GeneID:
109703069
NCBI-ProteinID:
XP_020043867
UniProt:
A0A8C0W7A5
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVVSRMLGVAQKSARRVLLTSCNFSNDATIDIKGCDLYRLEKGPPTTAVLTREE
GLRYYRAMQVVRRMELKADQLYKQKYIRGFCHLCDGQEACCVGLEAAINPSDHVITSYRA
HGICYIRGLSVKSILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYMGKNEICLTLYGDGAANQGQIAEAYNMAALWKLPCVFICENNRYAMGTAIERAAAST
DYYKRGNFIPGIRVNGMDVLCVREATKFAVEHCRSGKGPIVMELETYRYHGHSMSDPGIS
YRTREEIRIMRSKSDPIMLLQEKMISYKLTSVEELKEIDAEVRKEVEDAAQFAITDPEPG
LDELGHYLYSNNPTFDVRGANQWIKYKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggccgctgtggtctcccgcatgttgggggtcgcccagaagtcagct
cgcagagtgctgctgacttcctgtaacttttcaaatgacgctaccattgacattaagggt
tgtgatctttatcggttggaaaaggggccccccacgactgcggtgctcaccagggaggaa
gggctcagatactacagggccatgcaggtcgttcgccgcatggaattgaaggctgatcag
ctgtataagcagaagtatattcgtggcttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggtctcgaggcagcaataaacccctctgatcatgtcatcacgtcctatcgggct
catggcatatgctatatccgtggactctcggtcaagtccatcctggcggagctgacggga
agaagaggaggttgtgcgaagggaaaaggaggctccatgcacatgtatgccaagaacttc
tatgggggcaatggcatcgttggtgcgcaggtacccctgggagctggcattgcactggcc
tgtaaatacatggggaaaaatgaaatctgtttgactttatatggggatggcgctgctaac
caggggcagatagctgaagcttacaatatggcagccttgtggaaactaccttgtgtgttc
atctgtgagaataaccgctatgcaatgggcaccgctattgagagagcagcggccagcact
gattattacaagagaggcaattttatccctgggatcagggtgaatgggatggatgttcta
tgtgtccgggaggccacgaagtttgccgttgagcactgcaggtctggaaaggggcccata
gtgatggagctagagacctaccgttatcatggacacagcatgagcgatcctggaatcagt
tatcgcacacgagaagaaattcggatcatgagaagtaagagcgatccgattatgcttctc
caagagaaaatgataagctacaagctcaccagtgttgaagaattaaaggaaatagatgcg
gaagttaggaaggaagttgaggatgctgcccagtttgctataactgatccggaaccaggt
ttggatgaattaggccattacctctacagcaataatccaacttttgacgttcgtggtgca
aatcagtggatcaaatataagtccatcagttaa
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integrated database retrieval system
