Corynebacterium diphtheriae CDCE 8392: CDCE8392_1680
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Entry
CDCE8392_1680 CDS
T01700
Symbol
folC
Name
(GenBank) dihydrofolate synthase / folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cdd
Corynebacterium diphtheriae CDCE 8392
Pathway
cdd00790
Folate biosynthesis
cdd01100
Metabolic pathways
cdd01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cdd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CDCE8392_1680 (folC)
Enzymes [BR:
cdd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CDCE8392_1680 (folC)
6.3.2.17 tetrahydrofolate synthase
CDCE8392_1680 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AEX72666
LinkDB
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Position
complement(1768333..1769829)
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AA seq
498 aa
AA seq
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MKDEDLHLGEVSLNETGLSLPIDVNADTEAPAPREITADDLMDLATVEAELDQRWSEVKI
DPTLERVEMLMDLLGHPEHAFPAIHVAGTNGKTSTVRMIESLMRAFHRRTGRTTSPHLQL
VTERIAIDGQPIHPRDYVRTWNEIKPYVEMVDAHSEANGGPKMSKFEVLTAMAYAAFADA
PVDVAVVEVGMGGRWDATNVINSDVAVVMPVGLDHTDFLGDTIEKIAAEKAGIIKSRWDA
SDLLTPPDNVAIVAEQDPAAMNVILEQAVSVDASVARAGVEFAVMDAAIAVGGQQISIRG
LGGEYPDIFLPLSGEHQARNAATALAAVEAFFGAGAGRQLDLDTVREGFATVQSPGRLER
VRTAPTVFIDAAHNPHGAAALGKALERDFDFSRLIGVVAVLGDKDYVGVLRAFEPHLSEI
VVTTNSSPRALAADDLAEEARNIFGEERVHVAYSLPSAVELAVELAEDTEVQSGSGVIVT
GSVVTAGEARTLFGKDPA
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
gtgaaagacgaggatctccacctaggagaagtctccctgaacgagactggcctatcgctg
cctatcgacgtcaacgcggacaccgaagcacccgccccgcgcgagatcacggccgatgac
ctcatggatttggccaccgtcgaagcggagctggatcagcgctggtccgaggtcaaaatt
gaccccacgctcgagcgtgtggagatgttgatggatctgctggggcacccagaacatgcg
tttccggctattcacgtagccggaaccaacggcaagacgtcgacggtacgcatgatcgaa
tccctcatgcgtgctttccaccgccgcacgggacgcaccaccagcccgcaccttcagctg
gtcaccgaacgcattgctatcgacggccagccgatccaccctcgcgactacgtacgcacg
tggaacgagatcaaaccctatgtggagatggtcgacgctcattctgaggccaacggtggc
cccaagatgagcaagttcgaagtgctcacggccatggcctacgctgcgtttgcagacgca
ccagtggacgtcgcagtggtagaggtcggcatgggtggtcgctgggatgccaccaatgtg
attaactccgatgttgccgtagtgatgcccgtggggctggaccacacggatttcctcggc
gataccatcgagaaaatcgctgcagaaaaagctggcatcatcaagtcccgttgggatgcc
tccgacctgctgaccccgccggataacgtcgctatcgttgcggagcaagatcccgcggcg
atgaacgtgatccttgaacaggccgtgagcgtggatgcttctgtggcgcgcgccggtgtg
gaattcgcggtgatggatgctgctatcgcggttggtggtcaacagatcagtattcgtggc
ctaggtggcgagtaccccgacatcttcttgccactttctggcgagcaccaagcccgcaac
gcagcgaccgcattggctgctgtggaggctttcttcggtgcgggtgctggccgccagcta
gaccttgatacggttcgcgaaggttttgccaccgtgcagtccccaggtcgtctcgagcgg
gtgcgcactgctcccacggtatttatcgacgctgcccacaaccctcacggtgctgccgca
ttgggcaaagccttggagcgtgacttcgatttctcgcgcctcattggcgtggtagcagtg
cttggcgacaaagattacgtgggcgtgttgcgtgcctttgagccgcacctgtccgagatc
gtggtgaccacgaactcttcgccgcgcgctcttgctgccgatgaccttgccgaggaagca
cgcaacatctttggcgaagaacgcgtgcacgtggcgtactcgctgccgtcggcagtcgaa
ctggcagtggaacttgccgaggataccgaggtgcaatccggttccggtgtaatcgtcaca
ggctctgtggtcactgcgggtgaggcccgtaccctgtttggaaaggaccccgcatga
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