Clostridioides difficile R20291: CDR20291_3242
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Entry
CDR20291_3242 CDS
T00998
Symbol
hemD
Name
(GenBank) porphyrin biosynthesis protein includes: uroporphyrinogen-III methyltransferase and uroporphyrinogen-III synthase]
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cdl
Clostridioides difficile R20291
Pathway
cdl00860
Porphyrin metabolism
cdl01100
Metabolic pathways
cdl01110
Biosynthesis of secondary metabolites
cdl01120
Microbial metabolism in diverse environments
cdl01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cdl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CDR20291_3242 (hemD)
Enzymes [BR:
cdl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CDR20291_3242 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CDR20291_3242 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
CBE07177
UniProt:
A0A9R0BNE1
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Position
complement(3876506..3878005)
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AA seq
499 aa
AA seq
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MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLREAKPDCELIYVGKASS
NHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAETLVDEDIEFEVVPGITSA
IGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNALANNKGTLVFLMGISNLEKIS
ENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYETAIKEEVKPPTLIVVGSVVGLRE
KLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGGNPIEIPTIKVEKIQNNINLENEIK
NINKYNYLILTSKNAVEIFFEKIYEMNFDLRILSNLKVCAIGSATSNELKKRGIIADIVP
KKFVAESLYEELAPILNDNDNILIPRAENARDYLVDKLKAICEVTEVHIYRTVIDEDKKG
EILDILNSNDIDYITFTSSSTVNNLVEIIGKENIKILEKIKTLSIGPITTETINSLGIKL
YKESATSTIDSLVDLIIKN
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atgaagggtaaggtttacttagtaggggcaggaccaggtgattataaactcatgacttta
aaaggtttagagtgtataagaaaatcggatgtaatagtatatgatagattagcaaatagt
agttatttaagagaagctaagcctgattgtgaacttatatatgtaggcaaggcatcaagt
aatcatattttgccacaagaagatataaatagaattatagcagaaaaagctaaagaagga
aaaattgtaactcgtcttaaaggaggagacccttatgtatttggcagagggggagaagaa
gcagagactttagtagatgaagatatagaatttgaagtagttccaggtataacttctgct
ataggaggtttatgttatgcgggtattcctataacacatagagaccatgcttcgtcattt
catgtaataacaggtcatttgaagggtgatgatagtggagaattaaactggaatgctctt
gcaaataacaaaggtactcttgtgtttttgatgggaatttcaaacctagagaaaataagt
gaaaacttaatgaaagaaggaaaagataaggatacacctgttgctcttataagttgggca
actagatataatcaaagagttgttacatctacacttgagaatgtttatgaaactgctatt
aaagaagaagtaaaaccgccaactcttatagtagttgggagtgttgtaggacttagagaa
aagttgaacttctttgaaagtaagcctttatttggaaaaagtattgctgtaactaggtct
agaaatcaaaatagtgtattggtagaaaaaataatggatttaggtggaaatcctatagaa
atacctactattaaggtagaaaaaatacaaaataatattaacttagaaaatgaaataaaa
aatataaataagtataattatttaatactaactagtaaaaatgccgtagaaatcttcttt
gaaaagatatatgaaatgaattttgatttaaggatattatctaatttaaaggtatgtgct
ataggttctgctacatcaaatgagttgaaaaaaagaggaattatagcggatatagtacca
aaaaaatttgtagcagagtcactgtatgaagagttagctcctattttaaatgataacgat
aatatacttatacctagagcagaaaatgctagagattatctggttgacaaacttaaggct
atttgtgaagtaacagaagtacatatatatagaacagtaatagatgaggataaaaaaggt
gagatattagatattttaaattctaatgatatagattatataacatttactagttcctca
acagtaaataatcttgttgaaattataggaaaagaaaatattaaaatattagaaaaaata
aaaacactatctataggtcctataactacagagacaataaatagtttgggaataaaattg
tacaaagaatctgctacatctactatagattcgttagtagatttaattataaaaaattaa
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