Cellulosilyticum sp. WCF-2: EKH84_09815
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Entry
EKH84_09815 CDS
T06333
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cew
Cellulosilyticum sp. WCF-2
Pathway
cew00790
Folate biosynthesis
cew01100
Metabolic pathways
cew01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cew00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EKH84_09815
Enzymes [BR:
cew01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EKH84_09815
6.3.2.17 tetrahydrofolate synthase
EKH84_09815
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEH68654
UniProt:
A0A5B9YD03
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Position
2203532..2204854
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AA seq
440 aa
AA seq
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MYITTKSKGSLLMQEQRALELLNLFKSSTIKLGLKYISILMQRLGNPEDKLKIIHIGGTN
GKGSTTQFIRGILQEAGYKVGVFSSPELISPRENIRINHQDISKEAFLSYSSRVVQVAEE
MRQEDLAPSYFEILTGMALLYFYEQEVDFVILEVGMGGRLDATNVIKKPIMSIITKVAID
HTDFLGATLSEIATEKAGIIKSHSIVVTPSQEVEVMTVLQQAAKEKGAELVVADCAELKQ
VTVNEKGTCFELAGEVFQIRMLGVHQAYNCMIAIKAMRKLQEAYHMSLTEPQIKQGIKQV
VWEGRFEKLSEKPLVFIDGAHNVDGFMALSKTINQLPKRYTIGIIGILRDKEVEQMLPII
SKQFDILLVTEPNNLRSLKKEWLAEKLSAYSMKVEVMANIQEALVRALKIEKEYHGVSQI
IAFGSLYMIGEIRQRYLELI
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgtacattaccacaaaaagtaaagggagcttacttatgcaagaacaacgagctttagaa
ctcctaaacctatttaaaagtagcactattaaactaggattaaaatatataagtatattg
atgcagcgtttaggcaacccagaagataaactgaagataattcatataggtggtactaat
ggaaaaggttctacgactcagtttataagaggcatattacaagaagcaggctataaagta
ggggtgtttagttcaccagaacttatttctccaagagaaaatatacgtattaaccatcaa
gatatctcaaaagaagcttttctaagttattcaagtagagtagtgcaggttgcagaagaa
atgaggcaggaagacttagcaccttcgtattttgaaatcctaacaggaatggctttgcta
tacttttatgaacaagaggtggactttgttattttggaagtaggtatgggtggtagatta
gatgcaactaatgttattaagaaaccaatcatgtctattattactaaggttgctattgat
catactgactttttaggagccacattatctgaaattgctacagagaaagcgggtattata
aaatcacattcgatagtagttacaccaagtcaagaagtagaagtgatgacggttttacaa
caagcggccaaagaaaaaggggctgaattagtcgtagctgattgtgcagaacttaagcaa
gtaacagtgaatgaaaaaggtacttgttttgaactagcaggtgaagtttttcaaattcga
atgttaggtgttcatcaagcatataattgtatgattgctattaaagctatgaggaagctt
caagaagcctaccatatgtctttaacagaaccacaaataaaacaaggtataaagcaagtg
gtctgggaaggacgttttgaaaaactaagtgaaaaaccacttgtatttatagatggcgcg
cataatgtagacggatttatggcattatctaaaacgataaatcaattaccaaaacgttat
accataggcataataggtattttgagagataaagaagtagaacaaatgttaccgattatt
agcaaacagtttgatatactcttggtaactgagccgaataacctaagatctttaaaaaaa
gaatggttagcagaaaaactaagtgcttattcgatgaaggtagaagtaatggctaatatt
caagaagcactagtgagggcattgaaaattgaaaaagaataccacggtgttagtcaaata
attgcctttggttctttatatatgattggtgaaatacgtcagcgttatctggaactgata
taa
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