Canis lupus familiaris (dog): 119867228
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Entry
119867228 CDS
T01007
Symbol
PDHA2
Name
(RefSeq) LOW QUALITY PROTEIN: pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X3
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00010
Glycolysis / Gluconeogenesis
cfa00020
Citrate cycle (TCA cycle)
cfa00620
Pyruvate metabolism
cfa00785
Lipoic acid metabolism
cfa01100
Metabolic pathways
cfa01200
Carbon metabolism
cfa01210
2-Oxocarboxylic acid metabolism
cfa04066
HIF-1 signaling pathway
cfa04922
Glucagon signaling pathway
cfa05230
Central carbon metabolism in cancer
cfa05415
Diabetic cardiomyopathy
Module
cfa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119867228 (PDHA2)
00020 Citrate cycle (TCA cycle)
119867228 (PDHA2)
00620 Pyruvate metabolism
119867228 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119867228 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119867228 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119867228 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119867228 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119867228 (PDHA2)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119867228 (PDHA2)
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Motif
Pfam:
E1_dh
Motif
Other DBs
NCBI-GeneID:
119867228
NCBI-ProteinID:
XP_038318149
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Position
32:complement(23393738..23401128)
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AA seq
362 aa
AA seq
DB search
MATQREAPEGGREGSGTPGRLRVLVAPCNSAHGATFAIKKCDLGIPGAPPPPPPGPVTTV
LTREDGLRCYQAVQLVRIARTXRRISCIRGFGHLCDGQEXCRVGLEAGISPTGRXSTSCR
AQGSSSPRGISVRPVLAELTRRXGGGAXAKGGAMHTRVXPGPPRAATPVALGAGVAQAWR
YWGSQDVCGPLRGDGAANQGCXTAVARAPGPTVGGGDVLXAREAAKFAAADSPSEKGPVG
MELQACPXRGHSLSHPGTAPRRRGEXSEPIRLLEDRRANXLASTEAARRIGVEVRQEIED
AAQFAVSDPEPPSEEXGHHISRGNPPFEVRGADPWIKFKSLTLREAVMDLFAALQRNVPG
PL
NT seq
1089 nt
NT seq
+upstream
nt +downstream
nt
atggccactcagagggaggccccggagggaggccgcgagggcagcgggacccctgggcgc
ctgagggtgctggtggcaccctgtaactctgcacacggtgctacgtttgcaattaagaag
tgcgatcttgggatccctggggccccccccccccccccccccggcccggtgacaaccgtg
ctcacccgggaggatgggctcagatgctaccaggcggtgcagttagttcgcatcgcccgg
acctgaaggcggatcagctgtatccgtggattcggtcacttgtgcgacggtcaggaangg
tgtcgcgtgggcctggaggccgggatcagccccaccggtcgcnncagcacctcctgtcgg
gctcagggctcgagctcccctcgtggaatctccgtgcgacccgttctcgcagagctgacc
cggcggngcgggggcggagcttgagcgaaagggggcgcgatgcacacgcgggtcntgccg
ggacctcctagggcggcgaccccggttgccctgggagctggcgtcgcgcaggcctggagg
tactgggggagccaagacgtctgtgggccgctccgcggcgatggcgctgccaatcaggga
tgcngcacggctgtcgccagggccccgggaccgacggtggggggaggggatgtcctgtga
gctcgggaggcagctaagtttgcagcggccgacagcccatccgaaaaggggcccgtaggg
atggagctgcaggcctgcccttagcgcggacacagcctgagccaccctgggaccgcgccc
cgaagacgtggagagnncagcgagcccattaggctgctcgaggacaggagggcaaacnag
ctcgccagcaccgaagcggcgaggcgaatcggtgtggaagtgagacaggaaattgaggat
gccgcccagtttgctgtatctgatcctgaaccgccttcggaagaatgaggtcatcacatc
tcccgcggtaatccacctttcgaagttcgtggtgcagatccgtggatcaagtttaagtcc
ctcactctaagggaggctgtcatggatttatttgcagcccttcaaaggaacgttcctggt
ccgctttaa
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