Canis lupus familiaris (dog): 403607
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Entry
403607 CDS
T01007
Symbol
LIPE
Name
(RefSeq) hormone-sensitive lipase isoform X1
KO
K07188
hormone-sensitive lipase [EC:
3.1.1.79
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04024
cAMP signaling pathway
cfa04152
AMPK signaling pathway
cfa04371
Apelin signaling pathway
cfa04714
Thermogenesis
cfa04910
Insulin signaling pathway
cfa04923
Regulation of lipolysis in adipocytes
cfa04925
Aldosterone synthesis and secretion
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
403607 (LIPE)
04024 cAMP signaling pathway
403607 (LIPE)
04152 AMPK signaling pathway
403607 (LIPE)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
403607 (LIPE)
04923 Regulation of lipolysis in adipocytes
403607 (LIPE)
04925 Aldosterone synthesis and secretion
403607 (LIPE)
09159 Environmental adaptation
04714 Thermogenesis
403607 (LIPE)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.79 hormone-sensitive lipase
403607 (LIPE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HSL_N
Abhydrolase_3
BD-FAE
Say1_Mug180
COesterase
Motif
Other DBs
NCBI-GeneID:
403607
NCBI-ProteinID:
XP_005616592
Ensembl:
ENSCAFG00000004813
VGNC:
42695
UniProt:
A0A8P0N7K1
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Position
1:111412499..111431532
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AA seq
1097 aa
AA seq
DB search
MKPGRATPPEREVTTVEPDSKSLSRPDWEPKPHQTPITQPEPEPKVTATAQAVSKTHQGP
NTQQEPTLQQRPLTQQEPLAQHDAESQQEPSTHQNSALQKELLAPQEPAPQQSPPIHQVP
FSQQEVASQQAPGSGKEPETQWEPELREAKVAQPGPGPEQKPPAKQKDGTTPPIQPRPKI
RSPAQIESISQERMGHSDPKAQQTDPAQGAKSQQRSLIKWGFLSKLHQLSTQGPASEWRT
LFEWVTDSDSESDLRSPLKSNFPAKRSGTVAQGMKLASKGKHEVALGHGGTTAHGKKTGS
QSQRHYRDTGESEARGTGAFQGQSFIQLGGASRLTQNMDLRTMTQSLVTLAEDNMAFFSS
QGPGETARRLSGVFAGIREQALGLEPALGRLLSVAHLFDLDAETPANGYRSLVHTARCCL
AHLLHKSRYVASNRRSIFFRTSHNLAELEAYLVALTQLRALAYYAQRLLATNRPGGLFFE
GDEGLIAEFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLG
VTASSLFTSGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIEVLSSLANMASATVRV
SRLLSLPPEAFEMPLTADPKLTVTISPPLAHSGPGPVLVRLISYDLREGQDSEELSSLVK
SEGPRSLELRPRPQQAPRSQSLVVHIHGGGFVAQTSKSHEPYLKSWAQELGVPIVSIDYS
LAPEAPFPRALEECFYAYCWAVKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVR
VPDGIMAAYPATMLQSTASPSRLLSLMDPLLPLSVLTKCVSAYAGGETEDRSDSDQKALG
MMGLVRRDTALLFRDLRLGASSWLHSFLDLSGHKSHTNSVPTAEPMRRSVSEAALAQPEG
LLGTDSLKSLTLHDLSLKGSSDTSETPELSLSAETLGSSTPSNVNFLVGPEEAPEEAAKT
QELSAKDRGCGARAAFPEGFHPRRSSQGCTWMPVCSSPIVKNPFMSPLLASDSMLQSLPP
VHIVACALDPMLDDSVMFARRLRGLGKPVTLRVVEDLPHGFLSLAALCRETRHAAALCVE
RIRLVLTQPAAPSSPPL
NT seq
3294 nt
NT seq
+upstream
nt +downstream
nt
atgaaacctggaagagcaacacctcctgagagggaagtaacaacagtggagccagactct
aagtctctgtctaggcctgactgggaacctaagccacaccagacacctatcactcagcca
gagcctgagccaaaagtgacagccacagcccaggcagtatctaagactcatcagggaccc
aatactcaacaggaacccactctgcagcaaagacccctcactcagcaggagcctcttgcc
caacatgacgctgaatcccagcaggaacctagcacccaccaaaattcagctttgcagaag
gaacttcttgccccacaggagcctgcaccacagcaatcacctcccatccaccaggtgccc
ttttctcaacaggaagttgcctcacagcaggcacctgggtcaggaaaagagcctgaaact
caatgggaaccagaactgagagaggcaaaggttgcccagccaggacctggcccagagcag
aaacctccagctaagcaaaaagatggaacaacacctccaatccagcctagacccaagatt
agatcacctgctcagattgaatctatatcccaagagagaatgggacattcagaccctaaa
gcccagcaaacagatccagctcaaggagccaaatcccagcaaagatctctgatcaagtgg
ggatttctatcaaaactgcaccagctatccacacaggggccagcttcagagtggaggaca
ttgtttgagtgggtcacagattctgactcagaatcagatctgaggtctccattaaagagc
aattttccagccaagaggagtggaacagtggcccagggaatgaagctggcctccaagggg
aaacatgaagtggcattgggacacggtgggacaacggcacacgggaagaaaactggcagc
cagagtcaaagacactacagggacaccggtgagtctgaggccagaggaacgggagccttc
cagggacagtcatttattcagttgggaggagcctcgcggctcacacaaaacatggacctg
cgcacgatgacacagtcgctggtgactctggcagaagacaacatggccttcttctcgagc
cagggccctggggagaccgcacgacgactgtccggcgtctttgcgggtattcgggagcaa
gcgctgggactggagccagccctgggccgcctgctgagcgtggcgcacctcttcgacctg
gacgcagagacgccggccaatgggtaccgcagcctggtgcacacagcccgctgctgcctg
gcacacctgctacacaaatcccgctacgtggcctccaaccgccggagcatcttcttccgc
accagccacaacctggcggaactcgaggcctacctggtcgccctcacccagctccgtgcc
ctagcctactacgcccagcgcctgcttgccaccaaccggcctggggggctcttcttcgag
ggcgacgaggggctcattgctgaattcctgcgcgagtatgtcactctgcacaaaggctgc
ttctatggtcgctgtctgggcttccagttcacaccggccatccggccattcctgcagacc
atctccatcgggctggtgtccttcggggagcactataagcgcaatgaaacaggccttggt
gtgaccgccagctccctcttcaccagcggccggtttgccattgacccagagctgcgtggg
gctgagtttgagcggatcatacagaacctagatgtgcacttctggaaagccttctggaat
atcaccgagattgaggtgctgtcgtctctagcaaacatggcatcagccaccgtgagagta
agccgcctgctcagtctgccaccagaggcctttgaaatgccattgactgcggaccccaag
ctcacagtcaccatctcacctccactggcccacagtggcccggggccggtccttgtcagg
ctcatctcctatgacctgcgtgaaggacaggacagtgaggagctcagcagcctggtgaag
tccgaggggccccggagcctggagctgcggccacgcccacagcaggcaccccgctcacag
tccctggtggtgcacatccatggtggtggctttgtggcccagacctccaaatcccatgag
ccctacctcaagagctgggcccaggagctgggtgtccccatcgtctccatcgactactcc
ctggcccctgaggcccccttcccccgcgcactggaggagtgcttctacgcttactgctgg
gctgtcaagcactgtgccctcctcggctcgacaggggaacggatatgcctcgcaggagac
agtgcaggtgggaacctctgcttcaccgtgtcccttcgggcagcagcctatggggtgagg
gtgccagatggcatcatggcagcttacccggctacgatgctacaatctaccgcctcaccc
tcccgccttctgagcctcatggacccactgctgcccctcagcgtgctcaccaaatgtgtc
agcgcctatgctggtggagagacagaggaccgctctgactcagaccagaaggcactgggc
atgatggggctggtgcggcgggacacagccctgctcttccgagacctccgcctgggtgcc
tcctcatggctccactcattcttggacctgagtgggcacaagtcccatacgaattcagtg
cccacggcagagccgatgcgtcgcagcgtgtctgaggcagccctggcccagcctgagggc
ctgctgggcacagactccctcaagagcctgacactccatgacctgagcctaaagggcagc
tctgacacatcagagacccctgagctgtcgctgtctgcggagacactgggctcctccaca
ccctccaacgtcaacttcttagttggcccagaggaggcccccgaagaagccgccaagacg
caggagttgagcgccaaggacagaggctgtggcgcgcgagccgccttccctgagggtttc
caccccaggcgctccagccagggctgcacttggatgcccgtctgctcctcgcccatcgtc
aagaaccccttcatgtcgccgctgctggcgtctgacagcatgctacagagcctgccgccc
gtgcacattgtggcgtgtgcgctggaccccatgctggacgactcggtcatgttcgcgcgg
cggctgcgcggcctgggcaagccggtgacgctgcgcgtggtggaggacctgccgcacggc
ttcctgagcctggccgcgctgtgccgggagacgcgacacgccgccgcgctgtgcgtggag
cgcatccgtctggtcctcacccagcccgccgcgccctcctcaccgcccctctga
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