Canis lupus familiaris (dog): 403822 Help Entry 403822            CDS       T01007                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00220   Arginine biosynthesis cfa00330   Arginine and proline metabolism cfa01100   Metabolic pathways cfa04020   Calcium signaling pathway cfa04066   HIF-1 signaling pathway cfa04146   Peroxisome cfa04371   Apelin signaling pathway cfa04926   Relaxin signaling pathway cfa05010   Alzheimer disease cfa05014   Amyotrophic lateral sclerosis cfa05022   Pathways of neurodegeneration - multiple diseases cfa05133   Pertussis cfa05140   Leishmaniasis cfa05142   Chagas disease cfa05145   Toxoplasmosis cfa05146   Amoebiasis cfa05152   Tuberculosis cfa05200   Pathways in cancer cfa05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     403822 (NOS2)    00330 Arginine and proline metabolism     403822 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     403822 (NOS2)    04066 HIF-1 signaling pathway     403822 (NOS2)    04020 Calcium signaling pathway     403822 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     403822 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     403822 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     403822 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     403822 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     403822 (NOS2)    05152 Tuberculosis     403822 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     403822 (NOS2)    05145 Toxoplasmosis     403822 (NOS2)    05140 Leishmaniasis     403822 (NOS2)    05142 Chagas disease     403822 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     403822 (NOS2)    05014 Amyotrophic lateral sclerosis     403822 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     403822 (NOS2) Enzymes [BR:cfa01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      403822 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Motif Other DBs NCBI-GeneID:  403822 NCBI-ProteinID:  NP_001300777 Ensembl:  ENSCAFG00000018642 VGNC:  43895 UniProt:  O62699 A0A8C0T683 A0A8I3NVW8 LinkDB All DBs Position 9:complement(41328978..41365802) Genome browser AA seq 1157 aa AA seqDB search MACPWQFLFKAKSYQYDLTEKTDINNNVGKASQAPSSLVTQDDPKCHSLSKHRDESPQSL TGTVKTSPESTIKPAAPPLACPRHVRIKNWGNGMTFQDTLHHKAKGDLACKSKSCLGAIM NPKSLTREPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAKEMFEHICRHLRYASNNGNI RSAITVFPQRTDGKHDFRVWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYG RFDVVPLVLQADGQDPEFFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINV AVLHSFQKQNVTIMDHHSAAESFMKYMQSEYRSRGGCPADWIWLVPPISGSITPVFHQEM LNYVLSPFYYYQVEAWKTHVWQDEKRRPQRRKIQLKVLVKAVLFASMLMRKTMASRVRVT ILFATETGKSETLARDLGALFSCAFHPKVLCMDEYKLSHLEEEQLLLVVTSTFGNGDSPG NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPIGEGD ELSGQEEAFRCWAVQTFKAACETFDVRGKHCIQIPRLYTSNVTWDPHQYRLVQDSQPLDL NKALSRMHAKNVFTLRLKSQRNLQSPKSSRTTLLVELSCEDSQELSYLPGEHLGVFPGNQ LALVQGILERVVDSPAPHQPVHLETLSERGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ LLLRKLAQLATEEAERQRLEILCQPSEYNKWKLTNSPTFLEVLEEFPSLRVSAGFLLSQL PILKPRYYSISSSRDCTPMEVHLTVAVLVYPTRDGQGPLHHGVCSTWLSNLKPQDPVPCF VRSAGNFKLPEDPSRPCILIGPGTGIAPFRSFWQQRLHDIKHKGLRGSRMTLVFGCRRPD EDHLYREEMLEMAQSGVLHEVHTAYSRLPGQPKVYVQDILRQQLASQVLRMLHEEQGHLY VCGDVRMARDVAHTLKHLVAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDG AAKQPSDPRVPAAHGRS NT seq 3474 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccctggcagtttctgttcaaggccaaatcctaccagtacgacttgaccgag aaaacagacattaacaacaacgtggggaaagccagccaggccccctccagtctagtgaca caggatgaccccaagtgtcacagcctcagcaagcaccgggatgagtccccccagtccctc acagggacagtaaagacgtctccagaatccacaatcaagccagctgcgcccccactggcc tgcccacggcatgtgaggatcaaaaactggggcaacgggatgaccttccaagacacactt caccacaaggccaaaggggatctcgcttgcaagtccaagtcttgtctgggagccatcatg aaccccaaaagtttgaccagagaacccagggacaagccaacccccccagacgagcttcta cctcaagccattgaatttgtcaaccagtattacagctccttcaaagaggcaaaaatagag gaacatctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctatcag ctgacgggggatgagctcatcttcgccaccaagcaggcctggcgcaacgctccccgctgc atcgggaggatccagtggtccaacctccaggtctttgatgcccggagctgttccactgcc aaggaaatgtttgagcacatctgcaggcacctgcgttatgccagcaacaatggcaacatc aggtcggccatcaccgtgttcccccaacgaactgatgggaagcatgacttccgagtctgg aacgcccagctcatccgctatgctggctaccagatgcccgatggcaccatcctgggggac cctgccagtgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacggc cgctttgatgtggtgcctctggtgctgcaggctgatggccaagaccctgagttcttcgaa atcccacctgaccttgtgctcgaggtacccatggaacatcccaagtatgagtggttccgg gagctggagctgaagtggtacgccctgcctgcagtggccaacatgctgcttgaggtgggt ggccttgagttcccagggtgccccttcaacggctggtacatgggcacggagattggggtc cgggacttctgtgatgttcagcgctacaacatcctggaggaagtgggcagaaggatgggc ctggaaacacacaagctggcctcactctggaaggaccgggctgtcattgagatcaatgtc gctgtactccacagtttccagaagcaaaatgtgaccatcatggatcaccactcagctgca gagtccttcatgaagtacatgcagagcgagtaccgctcccgagggggctgccctgccgac tggatttggctggtccccccaatttctgggagcatcactcctgtgttccaccaggagatg ttaaattatgtcctgtcccctttctactactaccaggtggaggcctggaaaacccacgtg tggcaggatgagaagcggagaccccagaggagaaagattcaacttaaagtcttggttaaa gctgtgctttttgcctccatgctgatgcgcaagaccatggcatcccgagtcagagtcaca atcctctttgcgacagagacgggaaagtcagaaacgctagcccgggacctaggggccttg ttcagctgcgccttccaccccaaggttctctgcatggacgagtacaagctgagccacctg gaggaggagcagctactgttggtggtgaccagcacgtttgggaacggagactcccctggc aatggagagaaactaaaaaaatctctcttcatgctgaaagagcttaccaacaagttcagg tatgccgtgtttggcctcggctccagcatgtaccctcagttctgtgcctttgctcatgac atcgaccagaagctatcgcatctgggggcctctcagctcgccccaataggggaaggggat gagctcagtggacaggaggaagccttccgctgctgggccgtgcaaaccttcaaggcagcc tgtgagacgtttgatgtgcgaggcaaacactgcattcagatccccaggctctacacttcc aatgtgacctgggacccacaccaatacaggctcgtgcaggactcgcagcctctggacctc aacaaagccctcagcagaatgcatgccaagaacgtgttcaccctgaggctcaaatcacaa cggaatctacagagtccaaaatccagccgcaccactctcctggtcgagctctcctgtgag gacagccaggagctgagctacctgccaggagaacatctcggagttttcccaggcaaccag ctggccctggtgcaaggcatcttggagcgagtagtagacagccctgcaccccaccagcct gtgcacctggagaccctcagcgagaggggaagctactgggtcagagacaagcggctgcct ccgtgctcactcagccaggccctcacctacttcctggacatcaccactcccccgacccag ctgctgctccgaaagctggcacagctggccacagaagaggccgagaggcagaggttggag atcctgtgccagccctcagaatacaacaagtggaagttaaccaacagtcccaccttcctg gaggtgctggaggagttcccatccctgcgggtgtctgctggcttcctgctctcccagctc cctattctgaaaccgcggtactactccatcagctcctccagggactgcacacccatggag gtccacctcacggtggctgtgctcgtgtaccccacccgagatggccaaggtcctttgcac catggtgtctgtagcacatggctcagcaacctgaagccccaagacccagtaccctgcttt gtacgaagtgccggcaacttcaagctccccgaggatccctcccgtccttgcatcctcatt ggacctggcacaggcatcgcccccttccgcagtttctggcagcagcggctccatgacatc aagcacaaagggctccgaggcagccgcatgaccctggtgtttgggtgccgccgcccagat gaggaccacctgtatcgggaggagatgttggagatggcccagagtggggtgctgcatgag gtgcacacagcctattctcgcctgcctggccagcccaaggtctatgttcaagacatcctg cggcagcagctggccagccaggtgctccgcatgctccatgaggagcagggccacctttat gtctgtggggatgtgcgtatggcccgggatgtggcccataccctgaagcacctggtggct gccaagctgagcctgagtgaagagcaagttgaggactattttttccagcttaagagccag aagcgctatcatgaagatatctttggtgctgtgtttccctatgaggtgaaaaaagatggt gcagcaaaacagcccagcgatcccagagttccagcagcccacggaagaagttaa

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