Canis lupus familiaris (dog): 403832
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Entry
403832 CDS
T01007
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00562
Inositol phosphate metabolism
cfa01100
Metabolic pathways
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04068
FoxO signaling pathway
cfa04070
Phosphatidylinositol signaling system
cfa04071
Sphingolipid signaling pathway
cfa04115
p53 signaling pathway
cfa04140
Autophagy - animal
cfa04150
mTOR signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04218
Cellular senescence
cfa04510
Focal adhesion
cfa04931
Insulin resistance
cfa05165
Human papillomavirus infection
cfa05166
Human T-cell leukemia virus 1 infection
cfa05200
Pathways in cancer
cfa05206
MicroRNAs in cancer
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05213
Endometrial cancer
cfa05214
Glioma
cfa05215
Prostate cancer
cfa05218
Melanoma
cfa05222
Small cell lung cancer
cfa05224
Breast cancer
cfa05225
Hepatocellular carcinoma
cfa05230
Central carbon metabolism in cancer
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
403832 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
403832 (PTEN)
04070 Phosphatidylinositol signaling system
403832 (PTEN)
04071 Sphingolipid signaling pathway
403832 (PTEN)
04151 PI3K-Akt signaling pathway
403832 (PTEN)
04150 mTOR signaling pathway
403832 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
403832 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
403832 (PTEN)
04218 Cellular senescence
403832 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
403832 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
403832 (PTEN)
05206 MicroRNAs in cancer
403832 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
403832 (PTEN)
05230 Central carbon metabolism in cancer
403832 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
403832 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
403832 (PTEN)
05214 Glioma
403832 (PTEN)
05218 Melanoma
403832 (PTEN)
05215 Prostate cancer
403832 (PTEN)
05213 Endometrial cancer
403832 (PTEN)
05224 Breast cancer
403832 (PTEN)
05222 Small cell lung cancer
403832 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
403832 (PTEN)
05165 Human papillomavirus infection
403832 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
403832 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
403832 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
403832 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
cfa01009
]
403832 (PTEN)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
403832 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
403832 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
403832 (PTEN)
Protein phosphatases and associated proteins [BR:
cfa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
403832 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
403832
NCBI-ProteinID:
NP_001003192
Ensembl:
ENSCAFG00000015670
VGNC:
45138
UniProt:
P60483
LinkDB
All DBs
Position
26:37711222..37730964
Genome browser
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaggagatcgtcagcagaaacaaaaggcgctaccaggaggatggg
ttcgacttggacttgacctatatttatcccaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctgtgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttctaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatctattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtgtgcggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaacacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagaacgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatatttttctccaaat
tttaaggtgaagctgtacttcacaaaaactgtagaggagccatcaaacccggaggctagc
agttcaacttctgtgacgccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgacccagagaatgaaccctttgatgaagatcagcacacacaaatc
acaaaagtctga
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