Canis lupus familiaris (dog): 476574
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Entry
476574 CDS
T01007
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00010
Glycolysis / Gluconeogenesis
cfa00020
Citrate cycle (TCA cycle)
cfa00620
Pyruvate metabolism
cfa00785
Lipoic acid metabolism
cfa01100
Metabolic pathways
cfa01200
Carbon metabolism
cfa01210
2-Oxocarboxylic acid metabolism
cfa04066
HIF-1 signaling pathway
cfa04922
Glucagon signaling pathway
cfa05230
Central carbon metabolism in cancer
cfa05415
Diabetic cardiomyopathy
Module
cfa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
476574 (PDHB)
00020 Citrate cycle (TCA cycle)
476574 (PDHB)
00620 Pyruvate metabolism
476574 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
476574 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
476574 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
476574 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
476574 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
476574 (PDHB)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
476574 (PDHB)
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Gene cluster
GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
476574
NCBI-ProteinID:
XP_533778
Ensembl:
ENSCAFG00000007340
UniProt:
A0A8C0QIK1
A0A8I3S3U9
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All DBs
Position
20:32110558..32116683
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AA seq
359 aa
AA seq
DB search
MAAVSGLMRRPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPSEAQSKDFLIPIGKAKIERQGTHITVV
AHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLITVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgtctggcctgatgcggagacccctggaacaggtgtcggggttgctgagg
aggcgcttccaccggacggcgccggcggcgctgcaggtgacagttcgtgaggctataaac
caaggtatggatgaagagctggaaagagatgagaaggtatttctccttggggaagaagtt
gcccagtatgatggtgcatataaggttagtcgaggcctgtggaagaaatatggcgataag
agaatcatagatactcccatatctgagatgggctttgctggaattgctgtgggtgcagct
atggctgggttgaggcccatctgtgaatttatgaccttcaatttctctatgcaagccatt
gaccaagttataaattcagctgccaagacctactacatgtcggggggccttcagcctgtg
cctatagtcttcagggggcccaatggtgcctcagcaggtgtggctgcccaacactcacag
tgctttgctgcctggtatgggcactgcccaggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataataatccagtggtggtgcta
gagaacgaactgatgtatggagttccttttgaatttccctccgaagctcagtcaaaagat
tttctgattcccattggaaaagccaaaatagaaaggcaaggtacacacataactgtagtt
gctcattcaagacctgtgggccactgcttagaagctgcaacagtgttatccaaagagggt
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatctcataactgtggaaggaggctggccacagtttgga
gtaggagctgaaatttgtgccaggattatggaaggccctgcattcaatttcctggatgct
cctgcagttcgtgtcactggtgctgatgtccctatgccttatgcaaagattctagaagac
aactctgtacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatctag
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