Canis lupus familiaris (dog): 480726
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Entry
480726 CDS
T01007
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa03060
Protein export
cfa04141
Protein processing in endoplasmic reticulum
cfa04612
Antigen processing and presentation
cfa04918
Thyroid hormone synthesis
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
480726 (HSPA5)
04141 Protein processing in endoplasmic reticulum
480726 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
480726 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
480726 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
480726 (HSPA5)
05014 Amyotrophic lateral sclerosis
480726 (HSPA5)
05020 Prion disease
480726 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
480726 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
480726 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
cfa03110
]
480726 (HSPA5)
04131 Membrane trafficking [BR:
cfa04131
]
480726 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cfa04147
]
480726 (HSPA5)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
480726 (HSPA5)
Chaperones and folding catalysts [BR:
cfa03110
]
Heat shock proteins
HSP70 / DNAK
480726 (HSPA5)
Membrane trafficking [BR:
cfa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
480726 (HSPA5)
Exosome [BR:
cfa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
480726 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
480726 (HSPA5)
Exosomal proteins of colorectal cancer cells
480726 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Tombus_movement
Motif
Other DBs
NCBI-GeneID:
480726
NCBI-ProteinID:
XP_863385
Ensembl:
ENSCAFG00000020196
VGNC:
55608
LinkDB
All DBs
Position
9:57050544..57055478
Genome browser
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggcaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaatcgc
atcacgccgtcttatgtggccttcacgcctgaaggggagcgtctgatcggcgatgcggcc
aagaaccagctcacttccaaccccgagaacaccgtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccgtctgtgcaacaggacatcaagttcttgcctttcaaggtggtt
gagaagaagactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctaaccaaaatgaaggaaactgcggaggcttat
ttgggaaagaaggtaacccatgcagttgttactgtaccagcctacttcaatgatgcccaa
cgccaggcaaccaaagatgctggcactattgctgggttgaatgttatgaggatcattaat
gagcctacagcagctgctattgcttacggcttggataagagggaaggggagaagaatatc
ctggtgtttgacctgggtggtggaacttttgatgtgtctcttctcaccattgacaatggt
gtctttgaagttgtggctactaatggagatactcacctgggtggagaagactttgaccaa
cgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgggaggtagaaaaagccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctctgag
actctgactcgggccaaatttgaagagctaaatatggacctgttccgttctaccatgaag
cctgtccagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactagaattccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagacgaggctgtagcatatggtgctgctgtc
caggctggtgtactttctggtgatcaagatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcctctgataaccaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcacctcctggga
acttttgatctgactggaattcctcctgctcctcgtggagtcccacagattgaagtcacc
tttgagatagatgtgaatggcattcttcgtgtgaccgctgaagacaaaggtacgggcaac
aaaaataagatcacaattaccaatgatcaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
actagaaatgaattagaaagctatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcctctgaagataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaggctaaaaag
aaggaactggaggaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtag
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