KEGG   Canis lupus familiaris (dog): 482071
Entry
482071            CDS       T01007                                 
Symbol
CYP11B2
Name
(RefSeq) cytochrome P450 11B1, mitochondrial isoform X1
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00140  Steroid hormone biosynthesis
cfa01100  Metabolic pathways
cfa04927  Cortisol synthesis and secretion
cfa04934  Cushing syndrome
Module
cfa_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    482071 (CYP11B2)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    482071 (CYP11B2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    482071 (CYP11B2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cfa00199]
    482071 (CYP11B2)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     482071 (CYP11B2)
Cytochrome P450 [BR:cfa00199]
 Cytochrome P450, animal type
  CYP11 family
   482071 (CYP11B2)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 482071
NCBI-ProteinID: XP_038285385
Ensembl: ENSCAFG00000001285
LinkDB
Position
13:36823864..36833784
AA seq 503 aa
MAFRAQARGWRAGPWLALSRAPTLGTRAAPAPRAVLPFEAVPRCPGNKWMRVLQIWRQQG
SESLHLEMHRTFQELGPIFRYDVGGTHMVHVMLPEDVERLQRVESPQPWRPPLDPWLAYR
QHRGHKCGVFLLNGPEWRLNRLKLNPDVLSLQAVQKYIPMVDGVARDFSQALRARVLQNA
RGSLTLDIRPSILYYTVEASSLALFGERLGLLGPSPSPASLHFLQALEAMLRSTAQLLYL
PRGLSRWTSARVWKEHFESWDYIVQYANEAIQRIYQELALGRPQHYSGIVGELLLRADLS
PEAVRANCIELTAGSVDTTAYPLWMTLFELARNPDVQHALRQESQGAQAGIAENPQTAVT
ELPLLRAALKETLRLYPVGISVDRQVGSDVVLQNYHIPAGTLVKVQLYSLGRNPSVFERP
ERYHPQRWLDGRGSGTRAPSLAFGFGVRQCLGRRLAETEMLLLLHHVLNNFLVETLTHED
VKMVYRFIMMPSTLPLLTFRAIH
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggccttcagggcacaggcgcgagggtggcgggccgggccctggctggccttgagcagg
gcacccacactgggcacccgagccgctccggcccccagggcggtgctgcccttcgaagcc
gtgccccgctgtcccggcaacaagtggatgcgggtgctgcagatctggaggcagcagggc
tctgagagcctccacctggagatgcaccgcaccttccaggagctggggcccattttcagg
tatgacgtgggagggacacacatggtgcacgtgatgctgcccgaggacgtggagaggttg
cagcgagtggagagccctcagccctggcggccgcccctggacccctggctggcctaccga
cagcatcgtgggcacaaatgcggcgtgttcctgctaaacgggcccgagtggcgcctgaac
cgactgaagctgaacccggacgtgctgtcgctacaggccgtccagaagtacatccccatg
gtggacggggtggccagggacttctcacaggccctgagggcgagagtgctgcagaatgcc
cgcgggagtctgaccctggacatccggcccagcatcttgtactacaccgtagaagccagc
agtttggccctgttcggggagcggctgggcctgctgggccccagcccaagtcctgccagc
ctgcactttctccaggccctggaggccatgctgaggtccacggcccagctcctgtacctg
ccgcggggcctgtcgcgctggacgagtgccagggtgtggaaggagcactttgagtcctgg
gactacatcgtccagtacgccaacgaagccatccagaggatctaccaggagctggccctc
ggccgcccgcagcactacagcggcatcgtaggggagctgctgctgcgcgcggacctgagc
ccggaggccgtcagggccaactgcatcgagctcaccgccgggagcgtggacacgacagcc
taccccttgtggatgactctgttcgagctggctcgcaaccctgatgtgcagcacgccctg
cgccaggagagccagggggcccaggccggcatcgccgagaatccccagacagcagtcaca
gagctgcccctgctgcgggccgccctcaaggagaccctgaggctgtaccccgtgggtatc
tcggtggaccgccaggtgggctcggacgtggtgctgcagaactaccacatcccggcgggg
accttggtcaaggtgcagctctactccctgggtcgaaacccctccgtgttcgagaggccc
gagcgctatcatccccagcgctggctggacggccggggctccggcaccagggcccccagc
ctggccttcggctttggcgtgcgccagtgcctggggcggcgcctggccgagaccgagatg
ctgctgctgctgcaccacgtgctcaacaacttcctggtggagaccctcacccacgaggac
gtcaagatggtctaccgcttcataatgatgccctccaccctccccctgctcaccttccgg
gccatccactag

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