Canis lupus familiaris (dog): 607023
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Entry
607023 CDS
T01007
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01522
Endocrine resistance
cfa04010
MAPK signaling pathway
cfa04015
Rap1 signaling pathway
cfa04068
FoxO signaling pathway
cfa04071
Sphingolipid signaling pathway
cfa04114
Oocyte meiosis
cfa04148
Efferocytosis
cfa04218
Cellular senescence
cfa04261
Adrenergic signaling in cardiomyocytes
cfa04370
VEGF signaling pathway
cfa04380
Osteoclast differentiation
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04611
Platelet activation
cfa04613
Neutrophil extracellular trap formation
cfa04620
Toll-like receptor signaling pathway
cfa04621
NOD-like receptor signaling pathway
cfa04622
RIG-I-like receptor signaling pathway
cfa04625
C-type lectin receptor signaling pathway
cfa04657
IL-17 signaling pathway
cfa04658
Th1 and Th2 cell differentiation
cfa04659
Th17 cell differentiation
cfa04660
T cell receptor signaling pathway
cfa04664
Fc epsilon RI signaling pathway
cfa04668
TNF signaling pathway
cfa04670
Leukocyte transendothelial migration
cfa04714
Thermogenesis
cfa04722
Neurotrophin signaling pathway
cfa04723
Retrograde endocannabinoid signaling
cfa04728
Dopaminergic synapse
cfa04750
Inflammatory mediator regulation of TRP channels
cfa04912
GnRH signaling pathway
cfa04914
Progesterone-mediated oocyte maturation
cfa04917
Prolactin signaling pathway
cfa04926
Relaxin signaling pathway
cfa04932
Non-alcoholic fatty liver disease
cfa04933
AGE-RAGE signaling pathway in diabetic complications
cfa04935
Growth hormone synthesis, secretion and action
cfa04936
Alcoholic liver disease
cfa05014
Amyotrophic lateral sclerosis
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05132
Salmonella infection
cfa05133
Pertussis
cfa05135
Yersinia infection
cfa05140
Leishmaniasis
cfa05142
Chagas disease
cfa05145
Toxoplasmosis
cfa05152
Tuberculosis
cfa05161
Hepatitis B
cfa05163
Human cytomegalovirus infection
cfa05167
Kaposi sarcoma-associated herpesvirus infection
cfa05169
Epstein-Barr virus infection
cfa05170
Human immunodeficiency virus 1 infection
cfa05171
Coronavirus disease - COVID-19
cfa05205
Proteoglycans in cancer
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05415
Diabetic cardiomyopathy
cfa05417
Lipid and atherosclerosis
cfa05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
607023 (MAPK12)
04015 Rap1 signaling pathway
607023 (MAPK12)
04370 VEGF signaling pathway
607023 (MAPK12)
04668 TNF signaling pathway
607023 (MAPK12)
04068 FoxO signaling pathway
607023 (MAPK12)
04071 Sphingolipid signaling pathway
607023 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
607023 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
607023 (MAPK12)
04218 Cellular senescence
607023 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
607023 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
607023 (MAPK12)
04613 Neutrophil extracellular trap formation
607023 (MAPK12)
04620 Toll-like receptor signaling pathway
607023 (MAPK12)
04621 NOD-like receptor signaling pathway
607023 (MAPK12)
04622 RIG-I-like receptor signaling pathway
607023 (MAPK12)
04625 C-type lectin receptor signaling pathway
607023 (MAPK12)
04660 T cell receptor signaling pathway
607023 (MAPK12)
04658 Th1 and Th2 cell differentiation
607023 (MAPK12)
04659 Th17 cell differentiation
607023 (MAPK12)
04657 IL-17 signaling pathway
607023 (MAPK12)
04664 Fc epsilon RI signaling pathway
607023 (MAPK12)
04670 Leukocyte transendothelial migration
607023 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
607023 (MAPK12)
04914 Progesterone-mediated oocyte maturation
607023 (MAPK12)
04917 Prolactin signaling pathway
607023 (MAPK12)
04926 Relaxin signaling pathway
607023 (MAPK12)
04935 Growth hormone synthesis, secretion and action
607023 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
607023 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
607023 (MAPK12)
04723 Retrograde endocannabinoid signaling
607023 (MAPK12)
04722 Neurotrophin signaling pathway
607023 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
607023 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
607023 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
607023 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
607023 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
607023 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
607023 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
607023 (MAPK12)
05161 Hepatitis B
607023 (MAPK12)
05171 Coronavirus disease - COVID-19
607023 (MAPK12)
05163 Human cytomegalovirus infection
607023 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
607023 (MAPK12)
05169 Epstein-Barr virus infection
607023 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
607023 (MAPK12)
05135 Yersinia infection
607023 (MAPK12)
05133 Pertussis
607023 (MAPK12)
05152 Tuberculosis
607023 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
607023 (MAPK12)
05140 Leishmaniasis
607023 (MAPK12)
05142 Chagas disease
607023 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
607023 (MAPK12)
05020 Prion disease
607023 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
607023 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
607023 (MAPK12)
05418 Fluid shear stress and atherosclerosis
607023 (MAPK12)
05415 Diabetic cardiomyopathy
607023 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
607023 (MAPK12)
04932 Non-alcoholic fatty liver disease
607023 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
607023 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
607023 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
607023 (MAPK12)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
607023 (MAPK12)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
607023 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
607023
NCBI-ProteinID:
XP_038491608
Ensembl:
ENSCAFG00000000685
VGNC:
42993
LinkDB
All DBs
Position
10:16964857..16973137
Genome browser
AA seq
379 aa
AA seq
DB search
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRSGARVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENAPTPPGTPASPQVIGLLDVFTPDETLDDFTDFYLV
MPFMGTDLGKLMKHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELK
ILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSAGCIMAEMITGKTLFKG
SDHLDQLKEIMKVTGTPPAEFVQRLQSAEAKNYMKGLPELQKKDFASILTNASPLAVNLL
EKMLVLDAEQRVTAAEALTHPYFESLQDTEEEPKAQKYDESFDDVDRTLDEWKRVTYKEV
LSFKPPRQLGTKVSKETAL
NT seq
1140 nt
NT seq
+upstream
nt +downstream
nt
atgagctccccgccgcccgcccgcaggggcttctaccgccaagaggtgaccaagacggcg
tgggaggtgcgcgcagtgtaccaggacctgcagcccgtgggctcgggcgcctacggggcc
gtgtgctcggcggtggacagccgcagcggcgcccgggtggccatcaagaagctgtaccgg
cccttccagtccgagctgtttgccaagcgcgcctaccgcgagctgcgcctcctcaagcac
atgcgccacgagaacgcccccactccaccaggtactccggcctccccccaggtcattggg
ttgctggacgtgttcactcctgatgaaaccctggatgatttcacagacttttacctggtg
atgccattcatgggaactgacctgggcaagctcatgaagcacgagaagctgagtgaggat
cgaatccagttccttgtgtaccagatgctgaaggggctaaagtacatccacgccgccggc
atcatccacagggacctgaagcccggcaatctggcagtgaatgaggactgtgagctgaag
atcctggacttcggcctggccaggcaggcagatagcgagatgactggctacgtggtgacc
cggtggtaccgggcgcctgaggtcatcttgaactggatgcgctacacgcagacagtggac
atctggtccgcgggctgcatcatggcagagatgatcacggggaagacactgttcaagggc
agtgaccacctggaccagctgaaggagatcatgaaggtgacagggacgcctcccgccgag
ttcgtgcagaggctgcagagtgccgaggcgaagaactacatgaagggcctccccgagttg
cagaagaaggattttgcctccatcctgactaacgcaagccccctggccgtgaacctcctg
gagaagatgctggtgctggacgcagagcagcgggtgacggcggccgaggcgctgacccac
ccgtacttcgagtccctgcaggacacggaggaggagcccaaggcccagaagtacgacgag
tcctttgatgatgtggaccgcacgctggacgagtggaagcgtgtcacatataaagaagtg
ctcagcttcaagcctccccggcagctggggaccaaggtctccaaggagacagccctgtga
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integrated database retrieval system