Canis lupus familiaris (dog): 612452
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Entry
612452 CDS
T01007
Symbol
ALDH4A1
Name
(RefSeq) delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1
KO
K00294
1-pyrroline-5-carboxylate dehydrogenase [EC:
1.2.1.88
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00250
Alanine, aspartate and glutamate metabolism
cfa00330
Arginine and proline metabolism
cfa01100
Metabolic pathways
Module
cfa_M00970
Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
612452 (ALDH4A1)
00330 Arginine and proline metabolism
612452 (ALDH4A1)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
612452 (ALDH4A1)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-GeneID:
612452
NCBI-ProteinID:
XP_855272
Ensembl:
ENSCAFG00000041872
UniProt:
A0A8C0N6F0
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Position
2:76202258..76226797
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AA seq
564 aa
AA seq
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MLLPLPPALRRALLARPWRDPGLWWKHTSSLKVANEPVLAFTQGSPERDALQKALKDLKG
RTEAIPCVVGDEEVWTLDVQYQVSPFNHGHKVAKFCYADKALLNRAIEASLAARKEWDLK
PVADRAQIFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFLRFNAKFAVE
LEGQQPLSVPPSTNSVVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAM
LASYAVYRVFREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVA
QNLDRFRTFPRLAGECGGKNFHFVHRSADVGSVVSGTLRSAFEYGGQKCSACSRLYVPQS
LWPQIKGRLLEEHGRIKVGDPTEDFGTFFSAVIDAKSFGRIKKWLEHARSSPSLTILAGG
KCDDSVGYFVEPCIVESKDPQESIMKEEIFGPVLTVYVYPDDKYKETLRLVDSTTSYGLT
GAVFAQDKDVVREATTMLRNTAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYIL
RWTSPQVIKETHEPLGDWRYSYMQ
NT seq
1695 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgccgctgccgcccgcgctccgccgtgccctgctggcgcggccctggagggac
cccgggttgtggtggaagcacacctcttccctgaaggtggccaacgagccagtcttggca
ttcacgcagggcagccccgagcgagatgcgctccagaaggctttgaaggacctcaagggc
cggacggaagccatcccctgtgtggtgggggatgaggaggtgtggaccttggacgtgcag
taccaggtgtcgcccttcaaccatggacacaaggtggccaagttctgctatgcggacaag
gccctactcaacagagccatcgaggcctctttggccgccaggaaagagtgggacctgaag
cccgttgcagaccgggcccagatcttcctgaaggcggccgacatgctgagtgggcctcgc
agggcagaggtcctagccaagaccatggtgggacagggcaagacggtgatccaagcggag
attgacgcggcggcggagctcatcgacttcctccggttcaacgccaagtttgccgtggag
ctagaggggcagcagccgctcagtgtgccgcccagcaccaacagcgtcgtgtaccggggg
ctggagggcttcgtggcggctatctccccctttaacttcacggcgatcggcggcaacctg
gcgggggccccggccctgatgggcaacgtggtcctgtggaagcccagcgacacggccatg
ctggccagctatgccgtctaccgtgtcttccgggaggctggcctgccccccaatatcatc
cagtttgtgccggctgacgggcccacgtttggcgacaccgtcaccagctccgagcacctc
tgcggcatcaacttcacaggcagcgtgcccaccttcaaacacctgtggaagcaggtggcc
cagaacctagaccggttccgcaccttcccacgcctggccggagagtgcgggggcaagaac
ttccacttcgtgcaccgctcggccgacgtgggcagcgtggtgagcgggaccctgcgctcg
gccttcgagtacggcggccagaagtgctcagcgtgctcccgcctctacgtgccgcagtcg
ctgtggccacagatcaaagggcggctgctggaggagcacggcaggatcaaagtgggcgac
ccaacagaggatttcgggaccttcttctccgctgtgattgatgccaagtccttcggccgc
atcaagaagtggctggagcacgcccgctcctcacccagcctcaccatcctggccgggggc
aagtgtgacgactctgtgggctacttcgtggagccctgcatcgtcgagagcaaggaccct
caggagtccatcatgaaggaggagatcttcgggccggtgctgaccgtgtacgtctacccc
gacgacaagtacaaggagacgctgcggctggtcgacagcaccaccagctacggcctcacg
ggggcagtgttcgcccaggataaggacgtcgtccgggaggccaccacgatgctgaggaac
acggccggcaacttctacatcaacgacaagtccaccggctccgtggtgggccagcagccc
tttgggggggcccgagcctctggaaccaatgacaagccaggcgggccccactacatcctg
cggtggacgtcgccccaggtcatcaaggagacccacgagcctctgggcgattggcgctac
tcctacatgcagtga
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