KEGG   Camelus ferus (Wild Bactrian camel): 102514948
Entry
102514948         CDS       T02979                                 
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr04014  Ras signaling pathway
cfr04137  Mitophagy - animal
cfr04140  Autophagy - animal
cfr04620  Toll-like receptor signaling pathway
cfr04621  NOD-like receptor signaling pathway
cfr04622  RIG-I-like receptor signaling pathway
cfr04623  Cytosolic DNA-sensing pathway
cfr04657  IL-17 signaling pathway
cfr04936  Alcoholic liver disease
cfr05014  Amyotrophic lateral sclerosis
cfr05022  Pathways of neurodegeneration - multiple diseases
cfr05135  Yersinia infection
cfr05160  Hepatitis C
cfr05161  Hepatitis B
cfr05162  Measles
cfr05163  Human cytomegalovirus infection
cfr05164  Influenza A
cfr05165  Human papillomavirus infection
cfr05167  Kaposi sarcoma-associated herpesvirus infection
cfr05168  Herpes simplex virus 1 infection
cfr05169  Epstein-Barr virus infection
cfr05170  Human immunodeficiency virus 1 infection
cfr05171  Coronavirus disease - COVID-19
cfr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102514948 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102514948 (TBK1)
   04137 Mitophagy - animal
    102514948 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102514948 (TBK1)
   04621 NOD-like receptor signaling pathway
    102514948 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    102514948 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    102514948 (TBK1)
   04657 IL-17 signaling pathway
    102514948 (TBK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102514948 (TBK1)
   05161 Hepatitis B
    102514948 (TBK1)
   05160 Hepatitis C
    102514948 (TBK1)
   05171 Coronavirus disease - COVID-19
    102514948 (TBK1)
   05164 Influenza A
    102514948 (TBK1)
   05162 Measles
    102514948 (TBK1)
   05168 Herpes simplex virus 1 infection
    102514948 (TBK1)
   05163 Human cytomegalovirus infection
    102514948 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102514948 (TBK1)
   05169 Epstein-Barr virus infection
    102514948 (TBK1)
   05165 Human papillomavirus infection
    102514948 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102514948 (TBK1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102514948 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    102514948 (TBK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102514948 (TBK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102514948 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfr01001]
    102514948 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfr04131]
    102514948 (TBK1)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     102514948 (TBK1)
Protein kinases [BR:cfr01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   102514948 (TBK1)
Membrane trafficking [BR:cfr04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    102514948 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 Kinase-like CEP63 DUF713 COG6_N
Other DBs
NCBI-GeneID: 102514948
NCBI-ProteinID: XP_032349218
UniProt: A0A8B8U4P0
LinkDB
Position
12:32213966..32254959
AA seq 730 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLSTIGLIYEKIFLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWTHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFSKCDRG
QPVYHKEIMS
NT seq 2193 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcacctgtggcttttatctgatatcttaggccagggagctaca
gcaaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaagttatttgctattgaagaagagacaacaacaaga
cataaagtacttattatggaattttgtccgtgtgggagtttatacactgttttagaagaa
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagaaaatggcatagtccaccgtgatatcaagccaggaaat
atcatgcgtgtgataggggaagatggacagtctgtatacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagcgactggatcactgcca
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgtagtctttctcggggccttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgtattttcgctacaacaaatgaca
gctcataagatttatattcatagctacaatactgctaccgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaagggcgacgtttagtt
ctagaacctggaagactggcacagcatttccctaaaactactgaggaaaatcctatcttt
gtagtaagccgggaacctctgagtaccattggattgatatatgaaaaaattttcctgcct
aaagtacatccacgatatgatttagatggggatgccagcatggctaaggcaataacagga
gttgtgtgttatgcctgtaggattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggctgatagaactagttaaagatgattataatgaaactgttcacaaa
aagacggaagttgtgatcacattggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtctccag
gatattgaaagcaaactatctccaggtggattgctggcagatacatggacccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgttaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagattagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattatcatgcaacaaaagctatgacccac
tttacagatgaatgtgttaaaaagtacgaggcatttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatccctaactaatcagtgttttgatatt
gaagaagaagtttcaaaatatcaagattatacgaatgagttacaagaaactttgccacag
aaaatgtttgcagcctccagtgggatcaaacataccatgaccccaatttatccatgttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggta
gttaaagaacttgctgaaaataatcatattttagaaagattttcgaagtgtgatcgtgga
caacctgtatatcataaagagatcatgtcctaa

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