KEGG   Cricetulus griseus (Chinese hamster): 100754042
Entry
100754042         CDS       T02813                                 
Symbol
Mapk12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge01522  Endocrine resistance
cge04010  MAPK signaling pathway
cge04015  Rap1 signaling pathway
cge04068  FoxO signaling pathway
cge04071  Sphingolipid signaling pathway
cge04114  Oocyte meiosis
cge04148  Efferocytosis
cge04218  Cellular senescence
cge04261  Adrenergic signaling in cardiomyocytes
cge04370  VEGF signaling pathway
cge04380  Osteoclast differentiation
cge04550  Signaling pathways regulating pluripotency of stem cells
cge04611  Platelet activation
cge04613  Neutrophil extracellular trap formation
cge04620  Toll-like receptor signaling pathway
cge04621  NOD-like receptor signaling pathway
cge04622  RIG-I-like receptor signaling pathway
cge04625  C-type lectin receptor signaling pathway
cge04657  IL-17 signaling pathway
cge04658  Th1 and Th2 cell differentiation
cge04659  Th17 cell differentiation
cge04660  T cell receptor signaling pathway
cge04664  Fc epsilon RI signaling pathway
cge04668  TNF signaling pathway
cge04670  Leukocyte transendothelial migration
cge04714  Thermogenesis
cge04722  Neurotrophin signaling pathway
cge04723  Retrograde endocannabinoid signaling
cge04728  Dopaminergic synapse
cge04750  Inflammatory mediator regulation of TRP channels
cge04912  GnRH signaling pathway
cge04914  Progesterone-mediated oocyte maturation
cge04917  Prolactin signaling pathway
cge04926  Relaxin signaling pathway
cge04932  Non-alcoholic fatty liver disease
cge04933  AGE-RAGE signaling pathway in diabetic complications
cge04935  Growth hormone synthesis, secretion and action
cge04936  Alcoholic liver disease
cge05014  Amyotrophic lateral sclerosis
cge05020  Prion disease
cge05022  Pathways of neurodegeneration - multiple diseases
cge05132  Salmonella infection
cge05133  Pertussis
cge05135  Yersinia infection
cge05140  Leishmaniasis
cge05142  Chagas disease
cge05145  Toxoplasmosis
cge05152  Tuberculosis
cge05161  Hepatitis B
cge05163  Human cytomegalovirus infection
cge05167  Kaposi sarcoma-associated herpesvirus infection
cge05169  Epstein-Barr virus infection
cge05170  Human immunodeficiency virus 1 infection
cge05171  Coronavirus disease - COVID-19
cge05205  Proteoglycans in cancer
cge05208  Chemical carcinogenesis - reactive oxygen species
cge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cge05415  Diabetic cardiomyopathy
cge05417  Lipid and atherosclerosis
cge05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100754042 (Mapk12)
   04015 Rap1 signaling pathway
    100754042 (Mapk12)
   04370 VEGF signaling pathway
    100754042 (Mapk12)
   04668 TNF signaling pathway
    100754042 (Mapk12)
   04068 FoxO signaling pathway
    100754042 (Mapk12)
   04071 Sphingolipid signaling pathway
    100754042 (Mapk12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100754042 (Mapk12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100754042 (Mapk12)
   04218 Cellular senescence
    100754042 (Mapk12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100754042 (Mapk12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100754042 (Mapk12)
   04613 Neutrophil extracellular trap formation
    100754042 (Mapk12)
   04620 Toll-like receptor signaling pathway
    100754042 (Mapk12)
   04621 NOD-like receptor signaling pathway
    100754042 (Mapk12)
   04622 RIG-I-like receptor signaling pathway
    100754042 (Mapk12)
   04625 C-type lectin receptor signaling pathway
    100754042 (Mapk12)
   04660 T cell receptor signaling pathway
    100754042 (Mapk12)
   04658 Th1 and Th2 cell differentiation
    100754042 (Mapk12)
   04659 Th17 cell differentiation
    100754042 (Mapk12)
   04657 IL-17 signaling pathway
    100754042 (Mapk12)
   04664 Fc epsilon RI signaling pathway
    100754042 (Mapk12)
   04670 Leukocyte transendothelial migration
    100754042 (Mapk12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100754042 (Mapk12)
   04914 Progesterone-mediated oocyte maturation
    100754042 (Mapk12)
   04917 Prolactin signaling pathway
    100754042 (Mapk12)
   04926 Relaxin signaling pathway
    100754042 (Mapk12)
   04935 Growth hormone synthesis, secretion and action
    100754042 (Mapk12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100754042 (Mapk12)
  09156 Nervous system
   04728 Dopaminergic synapse
    100754042 (Mapk12)
   04723 Retrograde endocannabinoid signaling
    100754042 (Mapk12)
   04722 Neurotrophin signaling pathway
    100754042 (Mapk12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100754042 (Mapk12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100754042 (Mapk12)
  09159 Environmental adaptation
   04714 Thermogenesis
    100754042 (Mapk12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100754042 (Mapk12)
   05208 Chemical carcinogenesis - reactive oxygen species
    100754042 (Mapk12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100754042 (Mapk12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100754042 (Mapk12)
   05161 Hepatitis B
    100754042 (Mapk12)
   05171 Coronavirus disease - COVID-19
    100754042 (Mapk12)
   05163 Human cytomegalovirus infection
    100754042 (Mapk12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100754042 (Mapk12)
   05169 Epstein-Barr virus infection
    100754042 (Mapk12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100754042 (Mapk12)
   05135 Yersinia infection
    100754042 (Mapk12)
   05133 Pertussis
    100754042 (Mapk12)
   05152 Tuberculosis
    100754042 (Mapk12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100754042 (Mapk12)
   05140 Leishmaniasis
    100754042 (Mapk12)
   05142 Chagas disease
    100754042 (Mapk12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100754042 (Mapk12)
   05020 Prion disease
    100754042 (Mapk12)
   05022 Pathways of neurodegeneration - multiple diseases
    100754042 (Mapk12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100754042 (Mapk12)
   05418 Fluid shear stress and atherosclerosis
    100754042 (Mapk12)
   05415 Diabetic cardiomyopathy
    100754042 (Mapk12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100754042 (Mapk12)
   04932 Non-alcoholic fatty liver disease
    100754042 (Mapk12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100754042 (Mapk12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100754042 (Mapk12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100754042 (Mapk12)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100754042 (Mapk12)
Protein kinases [BR:cge01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100754042 (Mapk12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase UvrD_C Kinase-like
Other DBs
NCBI-GeneID: 100754042
NCBI-ProteinID: XP_027252038
UniProt: A0A8C2LI14
LinkDB
Position
2:complement(385885073..385894986)
AA seq 367 aa
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAIDSRTGNKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMK
VTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKMLVMDAEQRV
TAAEALAHPYFESLQDTEDEPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctccccgccacccgcccgcaagggcttttatcgccaggaggtgaccaaaacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgttggctctggtgcctatggtgca
gtgtgctctgcaatagacagtcgcactggtaacaaggtggccatcaagaagttgtaccgg
cccttccagtcggagctgtttgccaagcgcgcctacagagagctgcgcctcctcaaacat
atgcgccacgagaacgtgattgggctactggatgtgttcacacccgatgagactctggat
gacttcacagacttctacctggtgatgccattcatgggcactgatctgggcaagctgatg
aagcatgagactctgagtgaagacagaatccagtttcttgtgtatcagatgctgaagggg
ctgaagtatatccatgctgctggcgtcatccacagagacttgaagcctggaaacctggct
gtgaatgaggactgtgagctgaagatcctagactttggcctagccagacaggcagacagt
gagatgacaggctatgtggtgacccggtggtaccgggcaccagaggtcatcttgaattgg
atgcgctacacacagacagtggacatttggtctgttggctgcatcatggcggagatgatt
acaggaaagatcctgttcaaaggcaatgaccatctggaccagctgaaggagatcatgaag
gtcacagggacaccccctcctgagtttgtacagaagttacagagtgctgaggccaagaac
tacatggaaggcctccctgagctggaaaagaaggattttgcctctgtcctgaccaatgca
agccctcaggctgtgaaccttctggaaaagatgctggtgatggatgcagaacagcgggtg
acagcagctgaggcgctggcccatccatacttcgagtccttacaggacaccgaggatgag
cccaaggcccagaaatatgatgactcctttgatgatgtagaccgcacccttgaggaatgg
aagcgtgttacttacaaagaagtgctcagcttcaagcctcccaggcagctaggagccaga
gtcccaaaggagacagctctatga

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