KEGG T02813: 100762147

Cricetulus griseus (Chinese hamster): 100762147

Entry

100762147         CDS       T02813

Name

(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 6 isoform X1

K13369

17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]

Organism

cge Cricetulus griseus (Chinese hamster)

Pathway

cge00140

Steroid hormone biosynthesis

cge00830

Retinol metabolism

cge01100

Metabolic pathways

cge01240

Biosynthesis of cofactors

Module

cge_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

cge_M00977

C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:cge00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100762147
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100762147
Enzymes [BR:cge01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     100762147
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     100762147
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     100762147

SSDB

Motif

Pfam:

adh_short adh_short_C2 KR DUF1776

Other DBs

NCBI-GeneID:

100762147

NCBI-ProteinID:

XP_035307823

UniProt:

A0A3L7IHD5

LinkDB

Position

AA seq 317 aa
MWFYLVTLVGLYHLLRWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAAC
LTEKGAEELKSKTSDRLETVILDVTKTESIVAATQWTKERVGNRGLWGLVNNAAVPPALS
YLEWLQPEDSMAVFQVNFIGLAQVTLSMLPLVKKARGRIVNISSVLGRLAFSGGFYSCSK
YGVEAFSDILRREIQGFGVKVSIIEPGNFKTRMTDIELNIERIKKNWEAAPEHVKESYGQ
QFFDHFCRVTKENLMKRSTDLSLVTNCMEHALTSAYPRTRYPAGWDAWLLIIPLSYLPTS
LVDYILTRSRPKPAQAV

NT seq 954 nt +upstreamnt +downstreamnt
atgtggttctacctggtgacccttgtgggcctttatcaccttctgcgctggtaccgtgag
aggcaggtggtgagccatctccaagacaagtatgtcttcatcacgggctgtgactcgggc
tttgggaacctgctggccagacagctggacaggagaggcatgagggtgctggctgcatgt
ctgacggagaagggggccgaggagctgaagagcaagacatcagacaggctggagacagtg
atccttgatgtcaccaagacagagagtattgtggcagccactcagtggacgaaggaacga
gttgggaacagaggactctggggtttggttaacaatgcagctgttcccccagcactttcc
tacctcgagtggttgcaacctgaggactccatggctgtctttcaagtgaatttcattggt
ttggcccaggtgactctgagcatgcttcccttggtgaagaaggctcggggcaggattgtc
aatatctccagtgttttggggagactcgctttttctggaggattctacagttgttccaag
tatggagttgaagcattttcagatatactaaggcgtgagattcaaggttttggggtgaaa
gtcagcattattgaacctgggaactttaaaaccaggatgacagacatagagctaaacatt
gaaagaatcaagaaaaactgggaagcagcacctgagcacgtcaaggaatcctacggacag
cagttcttcgaccatttttgcagagtcaccaaagaaaacttgatgaagcgctctaccgac
ctgagcctcgtcaccaactgcatggagcacgcgctgacctctgcatatccacgcacccga
taccctgctggctgggatgcctggcttctcattatccctctatcttatttgcctacgtca
ctggtggactacatactgaccagatctcggcccaagccagctcaggcagtctga

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