Cricetulus griseus (Chinese hamster): 100771005
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Entry
100771005 CDS
T02813
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00310
Lysine degradation
cge01100
Metabolic pathways
cge05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100771005 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100771005 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cge03036
]
100771005 (Dot1l)
Enzymes [BR:
cge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100771005 (Dot1l)
Chromosome and associated proteins [BR:
cge03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100771005 (Dot1l)
HMT complexes
Dot1-containing complex
100771005 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
100771005
NCBI-ProteinID:
XP_027275106
UniProt:
A0A9J7G3B3
LinkDB
All DBs
Position
5:101534589..101578335
Genome browser
AA seq
1736 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSMKNPKLKEEQEAARRRQQRENKSNATTPTKVS
ENKAAATEAPVDSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAVN
AERKSKKSQSALDLLRSPPAAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKGTLSRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHVTGYEL
CNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHTGASKAAASEPHPRAEHAKESTLPYQSPGLSNSMKLSPQDPLPASPASSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQSRDASSTLEKQIGASTHGAGGSAAGSRSLALAPTGFYAGSVAISGALANSPAPLAS
GMESAVFDESSGTSSLFAIMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPRLSVTTQG
PLLDTSKGELPSDPAFSDPESEAKRRIVFSIAASSSSKQSPSTRHSPLTSSTRGDCVQSH
GQDSRKRSKRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESKSPPKTLENGGSLVGRKSAPSSEPVNSSKWKSTFSPISDLSLAKAVDS
PLQAGSALSHSPLFSFRPALEEPAAEAKLPTHPRKSFAGSLAAAEGPSPGANPPNGLAFS
GGLAADLGLHSFNDGASLSHKGPEVASLSASVSFPSQRGKDSTTDANPFLSRRQPEGLGG
LKGEGSAGKEPGETLPLCGPADKVALPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGL
LGGPGLVTVASSAGSVTPAAQAPRPFLSTFNPGPQFTLGPMSLQANLGSVAGSSVLQSLF
STVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSG
AVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPP
PPNVALPPPPALLAANSEPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLASLPHK
VSRPSFTVHHQPLPRLALAQAAPATPQASSSGPSAVWVSLGMPPPYAAHVSGVKPR
NT seq
5211 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgccagtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagattattgagact
atccggtgggtctgtgaggaaatcccggatctcaagctggccatggagaactacgtcctg
atcgactatgataccaaaagttttgaaagcatgcagaggctgtgtgacaagtacaaccga
gccatcgacagtatccaccagctgtggaagggcaccacacagcccatgaagctaaacact
cggccatctaatggactcctgcggcacatcctgcagcaggtgtacaaccactctgtaact
gaccccgagaagctcaacaactatgagcccttctcccctgaggtgtacggggagacctcc
tttgacctggttgcccagatgattgacgagatcaagatgaccgaggatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgcggccaccaactgcaaa
catcactacggagtggagaaagcggacatcccggccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggagcggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccaactgaaggagcgattcgcaaacatg
aaggaaggtggcagaatcgtttcctcaaagccctttgcccctctcaacttcaggatcaac
agcaggaatttgagtgacattggcaccatcatgcgtgtggtagagctgtcgcccctgaag
ggctccgtgtcatggactgggaagcctgtctcctactacctgcacactatcgaccggacc
atacttgaaaactatttttctagtatgaaaaatccaaaactcaaggaggaacaggaggca
gctcggcgccggcaacagcgagagaacaagagcaatgcaactactcccaccaaggtctca
gagaacaaggcagctgccaccgaggcgcctgtggactctggtgctgaggaagaaaagtca
ggtgtggccactgtcaaaaagccatcaccctccaaagcccggaagaagaagctaaacaag
aaagggaggaagatggctgggcggaagcgggggcggcccaagaaaatgagtgctgtgaac
gctgagcgcaagtcgaagaagagccaaagtgcactggacctcctgcgctcccctcccgca
gccccaccctcagcctcaccccaggatgcatacagggcacctcatagcccgttctaccag
ctacctccgagcacgcagctccactctcccaatccactgctggtggcgcccaccccgcct
gcgttacagaagcttttagagtccttcaaaatccagtacctgcagttcctggcgtacacg
aaaaccccacaatacaaggccaacctgcagcagcttctggaccaggagaaggagaagaac
acacagctgctgggcactgcacagcagctcttcggtcattgccaggcccaaaaggaggag
atccgaagactgttccagcagaagctggatgagttgggcgtgaaggctctgacctacaat
gacctgattcaggcccagaaggagatctctgcccacaaccagcagctgcgggagcagtcg
gaacagctggagaaggacaacagcgagctgcggagccagagcctgcggctgctcagggcc
cgatgtgaggagctgaggctggattggtccacattgtctctggagaacctgcggaaagag
aagcaggccctgcggagccagatctcagagaagcagcgacactgcctggagctgcagatc
agcattgtggagctggagaagagccagcgacagcaggagctcctgcagttgaagtcctgt
gtaccaccagatgacgctctgtccctgcatctgcgtggcaagggtaccctgagccgagag
ctggaggctgatgctgggcggttgcgtcttgagctggactgtgccaagatctccctgcca
cacctcagcagcatgagccctgagctctccatgaatggccatgtcactggctacgagctc
tgcaatgcagctagtcggccctcatccaaacagaacaccccccagtacctggcctccccc
ttggaccaggaggtagtaccctgcacccccagccacagtggccggcctcggctagaaaag
ttgtctggcctggctttgccagactacacccggttgtcaccagccaagattgtgttgagg
cggcacctgagccaggaccacactggggctagcaaagcagctgccagtgagccacaccct
cgggcggagcacgccaaggagagcacccttccctaccagagccctggcttgtccaacagc
atgaagctcagcccccaagacccactgcctgcctccccggcgtcctcaccactcacctca
gagaagggcagtgagaagggtgtgaaggagcgtgcctacagtagccacggggagactatc
accagcctgcctgttagcattccactcagcactgtgcagcccaacaagctgcctgtcagc
atcccactggccagcgtggtgctacccagccgcgccgagagggcgaggagcacgcccagc
cctgtgccacagtctcgagatgcctcatccacacttgaaaagcagatcggtgcttccacc
catggtgcagggggcagtgcagcagggagcaggagcctcgccttggcacccacaggcttc
tatgctggctcagtggccatcagtggggcgttggccaacagcccagctcctctggcctcg
gggatggaatcagctgttttcgacgagtcctctggcaccagcagcctctttgccatcatg
gggtctcgcagcacaccaccacagcacccacctctgctgccgcagcctcgaaactccggc
cctgcctctcctgcacaccaactctcagccagtccccgcctgagtgtgaccacccagggt
ccactgctggacaccagcaaaggggagctgccctctgaccctgccttctcagacccggag
agtgaagctaagaggagaattgtgttcagcattgcagccagctccagctcgaagcagtcg
ccttccactaggcacagccccttgacctccagcacccgtggggactgtgtacagagccat
gggcaggacagtcgtaagcgcagcaaaaggaagcgtgcgtcagctggaactcccagcctc
agcacaggtgtgtccccgaagcgccgggctctgccgactgtcgctggcctcttcacgcag
tcctcggggtctcccctcaacctcaactccatggtcagcaacatcaatcagcccctggag
atcacagccatctcgtcccctgagagctccctcaagagctcccccactccctaccaggac
catgatcagcccccagtgctcaggaaggagcggcccctgggcccgaccaatggggcccat
tactcaccactgacctcagatgaggagccaggctctgaagatgagcccagcagtgcccga
attgagagaaaaattgcaacaatctccttagaaagtaaatctcccccgaagacgctggaa
aatggtggtagcttggtgggaaggaagtctgccccctcaagtgagcctgtgaacagcagc
aaatggaagtccaccttctcacccatctctgacctcagcttggccaaggccgtggacagt
ccgctacaggctggctctgcgctgagccacagccccctgttctctttccggccagctctg
gaggagcctgctgctgaggccaagctccccacccacccaaggaagagtttcgctggctct
ctggctgcagctgagggcccgagccctggcgccaatcctcccaatggtctggccttcagt
gggggcctcgctgcagacctcggtttacacagcttcaatgatggtgcttccctctcccac
aagggccctgaagtggccagcctgagcgcctctgtgagcttcccatcacagcggggcaag
gacagtaccacagacgccaaccccttcctcagcaggcggcagccagagggtctgggtggc
ctgaagggcgagggcagtgcaggcaaggagcccggcgagacccttcccctgtgcgggcct
gcagacaaggttgcgttgcctcatggcagcagggccagcaagggtcgtgaccgggagctg
gacttcaagggcggccacaacctcttcatctctgctgcagctgtgcctccaggtggcctc
ctgggtggccctggccttgtaactgtggcttcctctgcgggcagtgtgacacctgctgcc
caggctccccggcccttcctgagtaccttcaaccctgggccccagttcactctgggcccc
atgtccctgcaggccaacctgggctctgtggctggctcctccgtgctgcagtccttgttc
agcactgtgccagctgctgcaggcttggtgcatgtatcatccactgcgacccgactgacc
aactcacacaccatgggcagcttctcctccggggtggccggcggaactgttggaggtgtc
tttacccatgcggtgccttctgcctctgctcacccgtttggagctggtgtcggcagcggg
gctgtgtgtagcagtgccacgctgggcctgagcccgctgcaggcggcggccagcacctcg
gcttcttcctttcaggccgcggcttcggttgagactaggccgccccctccacctcccctg
cttcctcctcagcacctgggccggccccctgcggggccacctgtcctccacgcaccccct
cctcctaacgttgccttgcctcctccgcctgcgctgctggccgctaactcagagccggtg
cttctgcagagcctggcctccctccccgctaacaaagctttcttacccccctcctctgcc
gcctctctgcagcctgctaacgcctctctgtctgtcaagctcgcctccctcccacacaag
gtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggccctggcgcag
gccgcgcccgccaccccgcaggccagctcctcggggccatctgctgtgtgggtttccctt
ggcatgccgcctccttatgccgcgcacgtttcgggggttaagcctcgataa
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