Cricetulus griseus (Chinese hamster): 100772790
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Entry
100772790 CDS
T02813
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X2
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00010
Glycolysis / Gluconeogenesis
cge00020
Citrate cycle (TCA cycle)
cge00620
Pyruvate metabolism
cge00785
Lipoic acid metabolism
cge01100
Metabolic pathways
cge01200
Carbon metabolism
cge01210
2-Oxocarboxylic acid metabolism
cge04066
HIF-1 signaling pathway
cge04922
Glucagon signaling pathway
cge05230
Central carbon metabolism in cancer
cge05415
Diabetic cardiomyopathy
Module
cge_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100772790
00020 Citrate cycle (TCA cycle)
100772790
00620 Pyruvate metabolism
100772790
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100772790
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100772790
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100772790
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100772790
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100772790
Enzymes [BR:
cge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100772790
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100772790
NCBI-ProteinID:
XP_027251220
UniProt:
A0A061ILA3
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Position
1
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AA seq
392 aa
AA seq
DB search
MRKMLAAVVSHVFSRASQKKPALRGLLASQNFSNDAPCHIKKCDLYRLEEGPPTTTVLTR
EEALKYYRAMQVIRRMELKSDQMYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHIITSY
RAHGLCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGKNFYGGNGIVGAQVPLGAGVA
FARKYLGTNEICLALYGDGAANQGQVAEAYNLSALWKLPCVFICENNRYGMGTATERAAA
STEYHKRGNFIPGLRVNGMDILCVREATKFAAHYCRSGKGPILMELQTYRYHGHSMSDPG
ISYRSREEVQNMRSKSDPIMLLRERMINNNLSNVEELKEIDADVKKEVEEAAQFATSDPE
PPLEELAYHLFYHSPPFGVRGTNKWITYKSVS
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggcggctgtggtgtcccatgtgttttcgcgagcgagccagaagaag
ccagctctgcgggggctgctggcatcgcagaacttctccaacgacgccccctgccacatc
aagaagtgcgacctgtaccggctggaggagggcccgcccaccacgacggtgctcacccgg
gaggaggccctcaagtactaccgggccatgcaggtgattcggcgcatggagctcaagtcg
gaccagatgtacaagcagaagttcatccgcggcttctgccacctgtgcgacgggcaggaa
gcctgctgcgtggggctggaggcaggcatcaaccccacggaccacatcatcacgtcctac
cgggcccacggcctgtgctacacgcgggggctgtcggtcaaatccatcctggccgagctg
acgggacgcaaggggggctgcgcgaaaggcaagggaggctccatgcacatgtacggcaag
aacttctacgggggcaacggcattgtcggggcccaggtgcccctgggcgccggtgtggcc
ttcgcccgcaaatacttgggaaccaacgagatctgcttggccttgtacggcgacggtgcg
gccaaccagggccaggtggcggaagcttacaacctgtcggccctgtggaaactaccctgc
gttttcatctgtgagaataaccgctacggaatggggacagccaccgagagggcagcagcc
agcaccgagtaccacaagagaggcaacttcatcccggggctgagggtgaacggaatggac
atcctctgtgtccgcgaggcgaccaagttcgcggctcactactgcaggtctgggaaaggg
cccattttgatggaactgcagacctaccgatatcatggacacagtatgagcgatccaggg
atcagttaccgttcgcgagaagaagttcaaaacatgcgaagcaagagcgatccgattatg
ctgctccgagagagaatgataaacaacaacctgagcaatgtggaggaattgaaggaaatc
gacgcggatgtgaaaaaagaagtcgaggaggcagcccagtttgctacatctgatcccgaa
ccacctttggaagagttagcctatcacctcttctaccacagtccgccttttggagtgcgt
ggtacaaataagtggatcacgtataagtccgtcagttag
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