KEGG   Cricetulus griseus (Chinese hamster): 107977023
Entry
107977023         CDS       T02813                                 
Name
(RefSeq) cytochrome P450 11B2, mitochondrial isoform X2
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00140  Steroid hormone biosynthesis
cge01100  Metabolic pathways
cge04927  Cortisol synthesis and secretion
cge04934  Cushing syndrome
Module
cge_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    107977023
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    107977023
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107977023
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cge00199]
    107977023
Enzymes [BR:cge01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     107977023
Cytochrome P450 [BR:cge00199]
 Cytochrome P450, animal type
  CYP11 family
   107977023
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 107977023
NCBI-ProteinID: XP_027260103
UniProt: A0A9J7FIA3
LinkDB
Position
2:complement(372631619..372637425)
AA seq 502 aa
MAMALRPKADVWLARPWQCLLRTRALGTTAALTPNTLRPFEAIPQYSRNRWLKMIQILRE
QGQENLHLEMHQAFQELGPIFRYSIGSTQIVSVMLPEDAEKLHQVESMHPRRMHLEPWVA
HREHRGLRRGVFLLNGPEWRLNRLRLNPHVLSPKAVQKFVPMVDMVARDFLEALKKKVFQ
NARGSLTMDVQQSLFNYSIEASNFALFGERLGLLGHDLSPDSLKFIHALHSVFKTTPQLM
FLPRSLTRWTSTRVWKEHFEAWDVISEYANRCIRKVHQELRLGNPHSYSGIVAELISQGA
LPLDAIKANSIELTAGSVDTTTFPLVMTLFELARNPDVQQALRQESLAAEASIAANPQRA
LTDLPLLRATLKETLRLYPVGGFLERILSSDLMLQNYHVPAGTLVLLYLYSMGRNPAVFP
RPERYTPQRWLERKRSFQHLAFGFGLRQCLGKRLAQVEMLLLLHHVLKSFKVETREQEDV
QMVYRFVLMPNSSPLLTFRPVS
NT seq 1509 nt   +upstreamnt  +downstreamnt
atggcaatggctctcaggccaaaggcagatgtgtggctggcaagaccttggcagtgtctt
ctcaggacgagggcactgggcaccacagcagcactgactcccaacacactgcggcccttt
gaagccataccacagtactccagaaacaggtggctgaagatgatacagatcctgagggag
cagggccaggagaacctgcacctggagatgcatcaggccttccaggaactggggcccatt
ttcaggtacagcataggaagcacacagattgtgtctgtgatgttgcccgaggatgctgag
aagctgcaccaggtggagagtatgcaccctcgtcggatgcacttagagccctgggtagcc
cacagagaacaccgtggcctgagacgtggagtgttcttgctaaatgggcctgaatggcgc
ttaaaccgactgaggctcaacccacatgtgctgtcaccaaaggctgttcagaagtttgtc
cccatggtggacatggtagcacgggacttcctggaggccctgaagaagaaggtgtttcag
aatgctcgtgggagcctcaccatggatgtgcagcaaagccttttcaactacagtatagaa
gcaagcaactttgctctttttggggagcgactgggcctccttggccatgacctgagtcct
gacagcctgaagttcatccatgccttgcattccgtgttcaagaccaccccacagctcatg
ttcttgcccaggagcttgactcgctggacaagcacccgggtgtggaaagaacattttgag
gcctgggatgtcatctctgagtatgccaacagatgtatccggaaggtgcaccaggagctc
agacttggcaatcctcattcctacagtggcatcgtggcagaactaatatcccagggagct
ttgcctctcgacgccatcaaagccaactctattgagctcaccgctgggagtgtagacacg
acaaccttccctctggtaatgaccctctttgagctggctcgaaacccagatgttcagcag
gcacttcggcaagagagcctggcagctgaggccagcattgcagcaaatcctcagagagct
ctaacagatctgcccctgttgcgggctaccttaaaagagaccttgaggctctatcctgtt
ggtggctttttggagagaattctaagctctgacttaatgcttcagaactaccatgttcct
gctgggacattagtcctactttatctctactccatgggccgaaaccctgcagtatttcca
aggccagagcgctacacgccccagcgctggctggagaggaaaaggagtttccagcacctg
gccttcggctttgggctacgccagtgcctggggaagcgcttggcacaggtggagatgctt
ctcctgctgcaccatgtgctgaaatccttcaaggtggagacacgagagcaagaggatgtg
cagatggtctaccgctttgttttgatgcccaactccagccccctcctcactttccggcct
gtaagctag

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