Carassius gibelio (silver crucian carp): 127945916 Help Entry 127945916         CDS       T08819                                  Name (RefSeq) obscurin-like isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism cgib  Carassius gibelio (silver crucian carp) Pathway cgib04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cgib00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     127945916  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cgib01001]     127945916   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cgib04131]     127945916 Enzymes [BR:cgib01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      127945916 Protein kinases [BR:cgib01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    127945916 Membrane trafficking [BR:cgib04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     127945916 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 C1-set Ig_6 Izumo-Ig Ig_5 V-set_CD47 fn3 C2-set_2 RhoGEF Adeno_E3_CR1 Sp38 CDC48_2 PH Ig_mannosidase IQ DUF1722 IQ_SEC7_PH COMM_HN Motif Other DBs NCBI-GeneID:  127945916 NCBI-ProteinID:  XP_052398008 LinkDB All DBs Position A24:complement(3205029..3260068) Genome browser AA seq 6975 aa AA seqDB search MDQNLFGGAPRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKDKMLLSAGGRFKKVE DGDVYRLTIYDLTLEDSGQYMCRAKNNVGEAYAAVTLKVGLPETVTDRAPVFTVKPVSTR VGLGDDVTFYCQVAAHPATNFDWEKDGRYLGETNRIKIISENDSSSLRIQSVRSLDSGTY TCRAQNSIGRAQAAAALAVDLQDTRLLNADKSTSLLSHMQKRKEDMRKDISLYRTVESSS TTHTASSSMVTEELGSLGLAHDQKQRVSALTSMLPKGVFTRTCMLTEGKHAKLSCFVTGH PKPQIIWRKDGANISEGRRHVMYEDQAENFILKVLYCKQSDNGLYTCNASNLAGQTYSAV LVIVKEPKIPFKKKLQDVEVKEKETATLLCEVPMPNTKASWFMEETHLEESTKYRMDVEG TLRRLTIHHVTTNDDAVYICEMKEGSRTVAELTVLGNITKKLPRKTVVPVSDTVIFCVEL EKPVDDAYWTRNGERLKEDFRIIIARINRQYTLTIRECTAEDSGEVAFIAHDCKTSTRFS VTAPRKHPPDAPVEPVVRNKTDSSITLCWSPPDSERPVPITGYIIERRKVGAQTWIKVTS TTVFSTEYTISEIPEEASYQFRISAVNDFGQSAYLDVPGTFYLEPTASVKAGLVNCRAHV GEEATFTVELSAVCSGSWTINDRLIRSGSEYLITRSKTTHTLVIREVSMELNGAQVKFVG GRSQSVATLCVKAAAAHFTSKYSQAEVFTFSLHSSAQMYTEVSDSSVQVVWLKNGKELRM GKKYEATSVERKRILTVHNVDREDVGIYECMCEGDKMSVQLALKEEPAKFLNKPRAQPQE NAALVGDVVLSCDVASPETAVVWKKEQIEITEDKRTTFISQGTQRKLVIRGAKQSDEGHY SCETAEDKMTFLVKIKETRAAFTNKDSYQKEVKVSSSQKATLSCEVSDIKTEVKWFKDGK QLISSKTVHMESKGKSRQLVLENVEKKDAGEYTCAVGNEKLVFKIWVEDIEAAFSNKDSY QKEVKVSASQKATLSCEVSDIKTEVKWFKDGKQLSSSKTVHMESKGKSRQLVLENVEKKD AGEYTCEVGNDKLAFKIWVEDIQAAFSNKDSYQKELRVPASQKATLSCEVSDPKTEVKWF KDGKQLSSSKTVQMESKGKIRQLVLENVQKKDAGEYTCAVGSEKLVFKIWVEDIQAAFSN KDSYQKEVKVSASQKATLSCEVSDIKTEVKWFKDGKQLSSSKTVHMESKDKSRQLVLENV EKKDAGEYTCAVGNEKLAFKIQVTDIQAAFTNKDSYQKEVKVATSQKTTLTCEVTDFKTE VKWFKDGKQLISSKTVHMESKDKSRQLVLENVEKKDAGEYTCAVGNEKLVFKIWVEDIEA AFSNKDSYQKEVKVSASQKATLSCEVSDIKTEVKWFKDGKQLISSKTVHMESKGKSRQLV LENVEKKDAGEYTCEVGNDKLAFKIWVEDIQAAFSNKDSYQKELRVPASQKATLSCEVSD PKTEVKWFKDGKQLSSSKTVQMESKGKIRQLVLENVQKKDAGEYTCAVGSEKLVFKIWVE DIQAAFSNKDSYQKEVKVSASQKATLSCEVSDIKTEVKWFKDGKQLSSSKTVHMESKDKS RQLVLENVEKKDAGEYTCAVGNEKLAFKIQVTDIQAAFTNKDSYQKEVKVATSQKTTLTC EVTDFKTEVKWFKDGKQLISSKTVHMESKDKSRQLVLENVEKKDAGEYTCAVGNEKLAFK IQVTDIQAAFTNKDSYQKEVKVAASQKATLSCEVSDPTTEVKWFKDGKQLSSSKTVHMES KGKIRQLLLENVEIKDAGEYTCEVGNEKLPFKIQVAELKAAFTNKDSYQKEVKVSASQKA TLSCEVSDLKTEVKWFKDGKQLSSSKTVHMESKGKIRQLVLENVEKKDAGEYTCAVGDEK LLFKIQLKDVSTKFQKTSVTKEIVMVESTEKVVLKTEVMSENCSVQWFRDGIELKDGSKY EMKQEGRSRVLIVKSSESKDSATYTCQTADDKVEFKVQVKDAPLKFVVPLQPVSAVLEST MTLSCTLNKATVNVLWKHNGKEIKPGGRFSIRTDGTNCILTVSAVAQEDEGEYSCECKDD KTTTKVTTKAPRLVRFTTRLNDVVANEGKDAIFKCSITPADVSVRWLRNDIPIIAGPKFM IAHGGSSHSLIITAVTQGDAGEISIDAEGKVCKATLQVQQLPVTFKKKLSDVTVTEQDTV RLEVELSKPSTDVKWMKNGVVLQQGENMEIHVDGAKQALVLKSVAYADRGQYSCETLDDK TQAKLTVEIKKIQIVKGIKEIKVQEKETITMEVELSKADVEGSWSKDGKKLKAGPNTIIT VVGNKHCLTMSQLKISDAGTITFQAEDVHTSGKLIVTEPAAKILKPLRDISSPEKEKIIF ECEVSRANADVKWFKNDEELKPGKKFGIHSQANKRTLIIHKCAYEDQGQYICRTTDDNTS AKLTVHARDIKIVKPLQDVEVTEKESATFVCEVSHDEVEAQWHKGDAKLKAGDNIKMRQE GRTYILLFKSVKTEDAGEIKFTAEKSSSAAKLKVKEQAISIVRELSSLEVTEPFAAHFEV EVSVETVKPVKWMLNGEQLKESADIEMEKEGTMHRLTFKKTKTSMSGLVQFIAGKSKSTA ELKVEERPIEVLEPLKDVSAKEKTSTTLCCKFSAPPKEVRWFKGQTALKASSKYNMKQKD ANVQLIIQSLSAEDSGEYRCQVGVCESKAILKVEVRKIQITKHLTDVEVDEDGDAVFTCE VNYADEEVQWTLNDKPLFSNEVNAITHVDKTHTLTLKNLAPQDGGKVSFSIRDVKETVCL KIKEKKAIFLKLLDDVVAEEKGTVTLKCEVSKPRVAPVWRKDGTFLSAGKKYELLHDGKT LGLTIHDVMQADAGEYSCDLGTDLSKSKVTVRDIHIGITKRFKSAEAKAGENCTFECILS RESSEKCTWSLKGQPVTDGGRFQISSKGRKYTLTIKAVSASDSGEVVFTLKDLSSKATLT VEGKAPAISKELQGVSARIGEDATFSCELSQSGLEVKWSKDGKSIRKSQKYEISQEQTLV KLTVCNVTEKDTGEYSCEVTGGPTSKAKLEIKELPNKFICELKDATAEEKSAVSFECETA QPASKVTWLKGTKEIRAGGRYELTQKGTVLILKVKDLEKSDSDVYTCDTGSAKSTANLTV KVVPARFKGQMKNQQVTEGGKVLLSCELSKPGCQVLWRKGTENLKHGGRYQITQRDTMCE LQISDLVPEDSGEYSCDCGNEKTTANVVVSALPVVFRHELQSQECDEGDSVTLHCELSKP GVPVVWKKGTQVLNSGEKYLIKQDGASVELKIADFRNEDAGQYTCLCGDKKTTANIKIKA LIFKRELQNQECQEADSVTLQCELSKPGVPVVWRKGTQVIHSGDKYQIKQVGSVFELKIT DVKPEDAGVYSCDCGFNKTSSTITVNALPVVFKHGLQNLECDEGGSATLSCELSKPGVPV QWKKGSHVIRSEGKYVIRQTASKVELKITDLKPEDEGDYTCVYGDKATTANMKIKVLKAQ TPSYQPGFQKQTTEQGPSIDALKFLRPSAALESDFQKQKKEKQAELSAHPIQFTEVLLNQ ACDEGGSVTLRCELSKPGVPVVWRKGTQVIHSGGKCLIKQVGSTVELKITDVKPEDAGAY VCDCGDSMTTANVKVNALPATFTQELKNQTAIEGESIIFHCELSKHGVPVVWRKGTQVIN SGGKYLIKQVGSTVELKISDVKPEDAGDYVCDCGDNITTANIKVNALPVVFKRELQNQEI QEGESVTLRCELSKPGVPVVWKKGTQVISSGGKYIIKQINSTVELKITDVKPEDAGDYVC DCGDSMTTANVKVNAIPATFIQELKNQTAIEGESIIFHCELSKPGVPVVWRKGTQVIHSG GKYLIKQVGSTVELKISDVKPEDAGDYVCDCGDNITTANIKVNALPVVFKRELQNQEIQE GESVTLRCELSKPGVPVVWRKGTQVIHSGGKYLIKQVGCTVEMKITDVKPEDAGDYACDC GDSITTANVKVNALPVIFTQALKNQTAVEGETISFQCELSKADILVEWRRGEIGLYPCAK YEFKQDGHRAQLIIHDLEPEDSGDYICDTGERQSFAYLEVKALPVLFKSSLKDLESEAGE NAVFRCELDKAGAKVIWRKDKSVIEASKKYQLKQDGAVAELIIYKLQGGDAGDYCCETEH DRTSAKLAVKEPDIIILTGLKSCIVNEGEDVHFECIVSHDNALIVQWTLQDVPLQNNERN EIRMEGKRHTLTLRSVTQKDSGTVSFHVGAHTSFACLTVKAIPVLSFVKELTSQEVTEGG SASLCCETSIPDSSVTWKKGTQVLSDGKKYSIKKNGTFQTLEIYKLSVDDGGEYICEVGD KQSKATLTVKECVKITRELKDVTVITGEDAIFQCEVSHTGVTNVEWWLGSNHLQNNDLNQ ISCRGREHSLVLKMVTPDDSGDVAFVVGPQKSIAYLLVQEKPKVIFLEKPLDLTAKEGQT VTLSCMTSDPEASVTWYKDEVMIKAGGRYLLYKDRAVHQLRILRVEEGDAGLYTCKTKDA ESCATLTVKGQPAYFRKELENQNAIEGDSITLLCELSKPVKSIEWRKGGVVLQPSKKFEM KQEGCVLELHVHNLESEDNGYYTCDAGAQLTTASLTVQEAEVLIVSGIKNIDVYVGEQAI FSCQLSRRAKGRVQWWLNGTRLENSTFSEISVGEDHVYTLTLRNLSPNYSGTVLFKTGGL TSSAKLLVKAKPIDILQELSNVETINGGEALFECSLSRPETKDCRWLIDGKPVKESAKVE IVSFESGRRHLLLLKDLHPCENTRVTFQAGASSTTALLSVKAWQLEVVKPLEDKTGIAGE QVEFTCVLNESVPETEVTWYANGVELQCNDQWAMKASGSSYSLILKKAQAQLTQEITFAA RNALSMAKLITISVPDPPEDPELVSKGPTFVTLSWFTPLSDGGSPIIGYRVEMRLVDSIL WLPCHTEPVCNTEFLVENLIPGAGYRFRVAAINRAGIGEPVQLPQTVTLDAPVTMTKMLS SSKIQKGKMVRLECELSTETKSVTWFKDNREIEFGVKYQMVAEGKSQVLLIKDFQSTDQG VYSCVASEEAKTSINLNLEGDDTTLSQDEGSQPKLPPEAASEGDLHALWDAVAKKRRMSR EPTLDSISELPEEDGKEKAQSKEGKGKKEKQVRPVEPPPKITAEPNLYTSSDEESLSGTT SLMSYLKKSSKSSVTETTASTKLYEHFQMTEQSVTKTSVEPLMEAPKGDELLEAAVKIQA AFKGYKARKDMRPVFKEVFKDQSKEPNGTIHLECIVEGKPDKVRWLKDGEPLTDGKHHHI DIYNDGTCSLVVTAATTKDTGVYTCEVTNKFGVSTHSGKVTVGTLRESSGRRPLTLGYSA DSEAESSSGSEMDETLRQASKRLRRLLRTHLPPDVEEESFVSADEGDLPPPALQTYREDD QYIYIRFDNRAEAQVASQRFQEMFTYQGVPIETAIIAAAGTKVELRITKMGLSQDGSKTP TQDQPMPAFMTGAPAAPIILTELRSQDVPDGFPVSFDCVIVGNPPPTVRWFKDGKMLEEN DHYMINEDQEGHHQLIITAVLPTDMGVYRCMAENDSAIASSKAELRVDMSCSSDYDTAAD ATETSSYVSAKGYVSSSEHRDTEAFESVAEDEQLPQILDELHDLFLSPGAPIAKMSVRVK GFPTPRVYWFKDGTPLQGSSRIVLSTKRDQHSLEILDVKREDTGEYSAYISNIAGSAYSS ARLNVQAPGERPAPVQRRMRDSKVPLVPPRFLERFSNKKVKQGASITLSVKVEGSPTPSV NWLKEVSDKDVLWIKADTPGYKVASSGRQHSLILMEVGKKHGGMYTCIATNLAGQSVNTA RLDVETAPEQKKVGPEVLGITISPPEEQGKGEIKLPSMGEVGTDEFLQKLTTQITEMVSA RITQASLRVPGADDDDDESKTPSPSPHHGRSRPPSLIADSSSESDEGDARGEMFEIYVVT ADYNPMGVSKDAIALKEGQYVEVLDSAHPLKWLVRTKPTKSHPSRQGWVSPAYLDKRLKL SADIADLPETSREEVSETEYKKKLCQLVQELINTETEFLKQMEFFTSHHLKHVEEQSTPP EITSQKETIFRNINDLKSFHSSSLLPGLQDCDTDDDIAMHFLRNSEGFEKYLQYFIGQLQ AESAISEKEVHQYFKDYTASELANVDPSEGPVLSINAYLQRPPERIQKYRALLKELIRNK ARNGQNCCLLEQAYAMVSSLSQRSENTHHVSLIESYPANLEALGEPIRQGPFIVWEGAPG IRTSSRGHHRHVFLFKNHVVICKQKRDTNTDTQAYVFKNMMKLTNIDVNETVEGDERVFE IWHEREDSVRKYTLQARTVIIKNSWLRDLRDLQLRYSMPAWSSPDFDSVLTDYTAELGQT VKLACKVTGAPKPQVTWYKDGHAVEADPHHIIIEDPDGSCTLILDNMTADDSGQYMCFAT SSAGNASTLGKITVQVPPRFVNKIRNATLYPGEDAQFTCTIQSAPSPKIRWFKDGKLLTD QEKFQTYSEACSGVLVLVIKNPGERDLGHYECELSNRLGSARCATQLITPAVAMARERRA NQAISIEVTEQETKMPKKTIIIEETITTVMKNTRTKRHPSPRPSPRGAHCSETSTPEPPR QRRTLARKTVPTLYVPEQEGATARNPRWVEVEETIEYKVNKSPKLPRRRGVSPSKFSPPG NPNTNNSNNKLLEEAMGAAMALQASSDTHEEETAQNVFEVPSGIVNMTTFEMSDPCVSDE ETIIAEPEDDELAARDCKMLTDGNRVLTLEDLEDYVPQAGETFSSGTDHHISVEKPSEIS VLQREINESVIGKPIVLNVVRPVPPAKPRKGLFGSFKEQISSMFSPGLSAGVSSQARREK IIPIHVTGEPSSNYSRHTSSFAKLEVQSMYCSVLQREKEGGLQSFKTQVSTQTRNYTPTG QVTLQISKKQPFENQ NT seq 20928 nt NT seq  +upstreamnt  +downstreamnt atggatcagaatttatttggcggggctccacgcttcctaactcgacccaaagccttctcg ttgtgcgtgggacgagatgcttccctcagctgcactattgtgggaaaccctgttcctgta gtcacctgggagaaagacaagatgcttctttctgcaggtggacgcttcaaaaaagtagaa gatggggatgtttaccgacttactatctatgatctaactctagaagacagcggtcagtac atgtgtcgagccaagaacaatgttggagaggcatatgcagctgtgaccctgaaggtggga ctgccggaaactgtgactgatcgcgccccagtgtttacagtaaagcctgtctccacccgt gtgggtctaggggatgatgttaccttctattgtcaggtggcagcccatccagcaaccaac tttgactgggaaaaggatggtcgctacctgggtgagaccaaccgcatcaagatcatctca gaaaatgactccagctccttgaggatccagagtgtcaggagcttggacagtggtacctac acctgccgtgcacagaactccattggccgtgctcaggccgctgctgcgctagcggtcgac cttcaagatactcgtctcctgaatgcagacaagagcacatccctcctctcacacatgcag aagcggaaagaagatatgcggaaggacatctccttataccgcaccgtggaaagttcctca accacgcatacagcctcatcttccatggtcacagaggaacttggaagcttgggactcgcc catgatcagaagcagagggtttcggccttaaccagcatgttgcccaaaggtgtgttcacc cgcacctgtatgctgaccgagggtaaacatgcaaagctcagctgtttcgtcacaggccat cccaaacctcagatcatctggaggaaggatggggcaaacatcagtgagggccgcagacat gtgatgtatgaggaccaggctgagaatttcatcctcaaggtgctctactgcaaacaaagt gataatggcctgtacacctgcaatgcatccaacttggctggacaaacctatagcgctgtg ctagtgattgtcaaagagccaaagattccattcaaaaagaagctgcaggatgttgaggtg aaggaaaaggaaacagcaacgttgctgtgtgaggtgccaatgccgaacacaaaggccagc tggtttatggaggagacccatctggaggaaagtaccaagtaccgcatggatgtggagggc actctgcgccgcctcactattcaccatgtcaccaccaatgatgatgctgtctacatctgt gagatgaaggaaggcagccgcactgtggccgaacttacagtgctgggcaacatcactaaa aagctgccgaggaagacagtggtgccagttagcgataccgtcatcttctgtgtggaactg gagaaaccagtagatgatgcatactggaccaggaatggggagaggctgaaagaggacttc cgaattattattgcccgaattaacagacagtacacactgacgattcgggaatgtactgcg gaagactcgggtgaagtggccttcatcgcccatgactgcaagacatccacccgcttctcc gtcacagccccaaggaaacatcccccagatgccccagttgagccagtggtgcggaacaag acggattcatcgatcacactgtgctggtctccaccagacagtgaacggcctgtacccatc actggctacatcattgagcgcaggaaggtgggagcccaaacctggattaaagtcactagt acaactgtgtttagcactgaatacaccatcagtgaaattccagaagaggcaagctatcag ttccgcatctcagcagtcaatgattttggtcagagtgcctatttggacgttcctggaacg ttttaccttgagcccacagcgtcagtgaaggcaggcctggttaactgcagggcacatgta ggcgaagaagcaactttcactgtggagctctcagccgtatgttccggctcctggacaata aatgacagattgattcgcagtggatctgagtatctgatcacacgctcaaagaccacacac acgctggtcatcagggaggtgtccatggaactgaatggagcacaggtcaagtttgtgggt ggtagatctcagagtgttgccacgctttgtgtgaaagccgcagctgcacatttcaccagt aaatattctcaggcggaggtgtttactttcagcttgcactcctctgctcagatgtacaca gaggtgtctgactcaagtgtccaggttgtatggctgaagaatgggaaggagctgagaatg ggtaaaaaatatgaagccacaagtgtggagcgcaaacgcatactgacagtccacaatgtt gaccgtgaagacgtgggcatctatgaatgcatgtgtgaaggcgataaaatgtctgtccaa cttgccctaaaagaagagccagcgaagtttcttaacaagccaagggctcagccccaggag aatgctgctctggtgggtgacgtggtgttgagctgtgatgttgcttctcctgaaactgct gttgtgtggaagaaagaacagatagaaataacggaggacaagaggacaacttttatatct caggggacacaaaggaagctggtcatcaggggtgccaagcagagcgatgaaggacactac tcgtgtgagacggcagaggacaaaatgacattcctggtcaagataaaagaaactcgcgct gctttcaccaacaaggactcttatcagaaggaagtgaaggtttcatcctcccaaaaagcc acactgagctgtgaagtttctgacatcaagactgaggtgaaatggttcaaggatggcaag cagttgatttccagtaagaccgtccacatggagtcaaagggcaagagtcgtcagctggtg ctggagaatgtggaaaagaaggatgctggagaatatacctgtgcagttggaaatgaaaag ctggtctttaagatttgggtggaagacattgaggccgccttctccaacaaggactcttat cagaaggaagtgaaggtctcagcgtcccagaaggccacactgagctgtgaagtttctgac atcaagactgaggtgaaatggttcaaggatggcaagcagttgagctccagtaagactgtc cacatggagtcaaagggcaagagtcgtcagctggtgctggagaatgtggaaaagaaggat gctggagaatatacctgtgaagttggaaatgataagctggcctttaagatttgggtggaa gacattcaagctgccttctccaacaaggattcctaccagaaggagctcagagtaccagcc tcccagaaggccacactgagctgtgaggtttctgaccccaagactgaggtgaaatggttc aaggatggcaagcagttgagctccagtaagactgtccagatggagtcaaagggcaagatc cgtcagctggtgctggagaatgtgcagaagaaggatgctggagaatatacctgtgcagtt ggaagtgaaaagctggtctttaagatttgggtggaagacattcaagccgccttctccaac aaggactcttatcagaaggaagtgaaggtctcagcgtcccagaaggccacactgagctgt gaagtttctgacatcaagactgaggtgaaatggttcaaggatggcaagcagttgagctcc agtaagacagtccacatggagtcaaaggacaagagtcgtcagctggtgctggagaatgtg gaaaagaaggatgctggagaatatacctgtgcagttggaaatgagaaacttgcctttaaa attcaagtgacagacattcaagctgcttttaccaacaaggactcctatcagaaggaagtt aaagtagcaacttcccagaagaccacactgacctgcgaagttactgactttaagactgag gtgaaatggttcaaggatggcaagcagttgatttccagtaagaccgtccacatggagtca aaggacaagagtcgtcagctggtgctggagaatgtggagaagaaggatgctggagaatat acctgtgcagttggaaatgaaaagctggtctttaagatttgggtggaagacattgaggcc gccttctccaacaaggactcttatcagaaggaagtgaaggtctcagcgtcccagaaggcc acactgagctgtgaagtttctgacatcaagactgaggtgaaatggttcaaggatggcaag cagttgatttccagtaagaccgtccacatggagtcaaagggcaagagtcgtcagctggtg ctggagaatgtggaaaagaaggatgctggagaatatacctgtgaagttggaaatgataag ctggcctttaagatttgggtggaagacattcaagctgccttctccaacaaggattcctac cagaaggagctcagagtaccagcctcccagaaggccacactgagctgtgaggtttctgac cccaagactgaggtgaaatggttcaaggatggcaagcagttgagctccagtaagactgtc cagatggagtcaaagggcaagatccgtcagctggtgctggagaatgtgcagaagaaggat gctggagaatatacctgtgcagttggaagtgaaaagctggtctttaagatttgggtggaa gacattcaagccgccttctccaacaaggactcttatcagaaggaagtgaaggtctcagcg tcccagaaggccacactgagctgtgaagtttctgacatcaagactgaggtgaaatggttc aaggatggcaagcagttgagctccagtaagactgtccacatggagtcaaaggacaagagt cgtcagctggtgctggagaatgtggaaaagaaggatgctggagaatatacctgtgcagtt ggaaatgagaaacttgcctttaaaattcaagtgacagacattcaagctgcttttaccaac aaggactcctatcagaaggaagttaaagtagcaacttcccagaagaccacactgacctgc gaagttactgactttaagactgaggtgaaatggttcaaggatggcaagcagttgatttcc agtaagaccgtccacatggagtcaaaggacaagagtcgtcagctggtgctggagaatgtg gagaagaaggatgctggagaatatacctgtgcagttgggaatgagaaacttgcctttaaa attcaggtgacagatattcaagctgccttcaccaacaaagactcctatcagaaggaagtg aaagtagctgcttcccaaaaagccacactgagctgtgaggtttctgaccccacgactgaa gtgaaatggtttaaagatggcaagcagttgagctccagtaagaccgtccacatggagtca aagggcaagatccgtcagctgctgctggagaatgtggagataaaggatgctggagaatat acctgtgaagttgggaatgaaaagctgccatttaagattcaggttgcagagcttaaagct gcatttaccaacaaggactcttatcagaaggaagtgaaggtctcagcgtcccagaaagcc acactgagctgtgaagtttctgacctgaagactgaggtgaaatggttcaaggatggcaag cagttgagctccagtaagaccgtccacatggagtcaaagggcaagatccgtcagctagtg ctggagaatgtggaaaagaaggatgctggagaatacacctgtgcagttggagatgagaaa cttctcttcaagattcagctgaaagatgtttctaccaaattccagaagacatctgtgaca aaagaaattgtgatggttgagtcaacagaaaaggttgttttaaaaaccgaggtaatgtcg gagaattgtagtgttcagtggttcagggatggaatagaactgaaagacggatcaaagtat gagatgaaacaggaaggtcgctcacgtgtcctcatcgttaagtcctctgaatctaaagac agcgccacctacacttgtcagacggctgatgacaaagtggagttcaaggttcaagtcaaa gatgcacctttaaagtttgtggtgcctttgcagccagtgtctgcagtactagaaagcacc atgacactttcctgcactctcaacaaagccactgttaatgtcctctggaagcataacggc aaagaaatcaaacccggtggaagattcagcatccgcaccgatggcaccaactgcatcttg actgtctccgctgtggctcaggaggatgaaggggagtacagctgtgaatgtaaagatgac aagaccaccaccaaagtcactaccaaagccccacgactggtgaggttcactaccaggctg aacgatgttgttgcaaatgaaggcaaagatgctatctttaaatgctccatcacaccagct gatgtaagtgtcagatggctgcgtaatgacattcctattatagctggtcccaaatttatg attgctcatggagggagcagtcattccctcatcatcacagctgtcactcagggggatgca 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cagtggcacaaaggagatgccaaactcaaagccggagacaacataaagatgaggcaggag ggaagaacatacattctgctcttcaaatctgtaaagactgaggatgcaggtgaaatcaag ttcacagctgagaagtcctcttcagctgctaaactgaaggttaaagagcaggctatcagc atagtacgggaactgagttctttggaggtgaccgagccatttgctgcccactttgaggtg gaagtcagcgtggagacagtcaagccagtgaagtggatgctaaatggggaacagctgaag gagagtgccgacatcgagatggagaaagaaggaaccatgcaccggctcacttttaaaaag actaagacctccatgtcaggactggtacagttcattgccggaaagagtaaatcaacagcc gagctcaaagtggaagagcgtcccattgaagtcctggagcctctcaaagatgtttcagcc aaggagaagacttccaccacactatgctgcaagttctctgccccaccaaaagaagtacgg tggtttaagggtcaaactgctttgaaggcttctagcaaatacaacatgaagcaaaaggac gctaatgtgcagctgatcatacaaagtttgagtgcagaggactctggagagtatcgttgt caggtcggggtctgtgagagcaaagccattctcaaagtagaagtacgtaaaatccagatc accaaacatctgacagatgtggaggtggatgaagatggtgatgctgtgttcacatgtgag gttaactatgctgatgaagaggtccagtggacactcaatgacaagccactcttcagcaat gaggtcaatgccatcacccatgtggataagacccatacgctcaccctcaagaacctagca cctcaggatggtggaaaggtgtcatttagcatcagggatgtgaaagaaacagtctgccta aagatcaaagagaaaaaagccatcttcctgaagttgctggatgatgtagttgcagaggag aaaggtacagttacccttaagtgtgaagtctcaaagcccagagtggcccctgtgtggcgc aaagatggtacattcctgtcggcaggcaaaaagtatgagctcctccatgatggtaagacc ttgggacttactatccatgatgtcatgcaagctgacgccggggagtacagctgtgatctt ggcacagacctctccaagtccaaggtcactgttagagatatccacattgggatcaccaag cgttttaagtcagcagaggccaaagcaggtgaaaactgcacatttgagtgtatcttgtcc cgagagagctcagagaagtgcacctggagcctaaaaggtcaacctgtcactgatggaggc cgtttccaaataagcagcaaagggcgcaagtataccttaacaatcaaagccgtctcagct tctgattctggtgaggtggtcttcacgctcaaggatttgagctcaaaggcaacacttact gttgagggtaaagctcctgccatatctaaagagcttcagggtgtcagtgccagaattggt gaagatgccacattctcctgtgagctttctcaatctggactcgaagtgaagtggtcaaag gatggcaagtctatcagaaaaagccagaaatatgaaatcagtcaggagcagacgcttgta aagctgacagtctgcaacgtcactgaaaaagacactggagaatacagctgtgaggtcacc ggtggtccaacctccaaggctaaactggagatcaaagaactgcccaacaaattcatttgt gaactaaaggatgccactgcagaagagaagagtgctgtctcctttgaatgtgagacagcc caacctgcctctaaagtcacctggctgaaaggaacaaaggagatcagggctggaggaagg 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tgtgatgaaggaggcagtgctactctgtcctgcgagctttccaaacctggtgtccctgtg cagtggaaaaaaggaagccatgttatccgatctgaaggaaagtacgtcatcagacagact gcctcaaaggtggagctgaagattacagatctcaaacctgaagatgaaggagactacaca tgtgtatatggagacaaggcaaccactgccaatatgaagataaaggttctgaaggcccaa acaccctcataccaaccaggatttcaaaagcagactactgagcaagggccatcaattgat gctctaaagttcctccgtccttctgctgcccttgaatcagacttccagaagcagaagaaa gagaaacaggcagagctcagtgctcacccaattcagtttacggaagtactgctaaaccaa gcgtgtgatgaaggtggcagtgttactctgcgatgtgaactctcaaagcctggagttcct gtggtttggaggaaaggaacacaggtgatccattctggaggaaagtgcctcatcaaacaa gttggctctacggttgagctgaagatcactgatgtcaaacctgaagatgctggggcctat gtttgtgattgcggagacagcatgacaactgccaatgtcaaagttaacgctcttccagcc accttcacacaagagctgaaaaaccagacagctattgaaggagaaagtatcatcttccat tgtgagctctccaaacatggagttcctgtggtttggaggaaagggacacaggtgattaat tctggaggaaagtacctcatcaaacaagttggctctacggttgagctgaagatctctgat gttaaacctgaagacgctggagattatgtttgtgattgtggagataacatcaccactgct aacatcaaagtcaatgcattaccagtggtcttcaaacgtgagctacagaaccaagagatt caggaaggggaaagtgttactttgcggtgtgaactctcaaaacctggcgttcctgtggtt tggaagaaaggaacacaggtgatcagttctggaggaaagtacatcatcaagcaaattaac tctactgttgagctgaagatcactgatgtcaaacctgaagatgctggagattatgtttgt gattgcggagacagcatgacaactgccaatgtcaaagttaacgctattccagccaccttc atacaagagctgaaaaaccagacagctattgaaggagaaagtatcatcttccattgtgag ctctccaaacctggagttccagtagtttggaggaaagggacacaggtgatccattctgga ggaaagtacctcatcaaacaagttggctctacggttgagttgaagatctctgatgttaaa cctgaagacgctggagattatgtttgtgattgtggagataacatcaccactgctaacatc aaagtcaatgcattaccagtggtcttcaaacgtgagctgcagaaccaagagattcaggaa ggggaaagtgttactttgcgatgtgaactttcaaaacctggcgttcctgtggtttggagg aaaggaacacaggtgatccattccggaggaaagtacctcatcaaacaagttggctgtact gtcgagatgaagatcactgatgttaaacctgaagatgctggagactatgcttgtgattgc ggagacagcattactacagccaatgtcaaggttaatgcacttccagtcatcttcacacaa gcactgaagaaccagacagctgttgagggagagaccatcagcttccagtgtgaactctcc aaagcagacattctagttgagtggcgcaggggggaaattggcctatacccctgtgctaaa tatgaattcaagcaagatggccaccgtgcccaactgatcatacatgaccttgaacctgag gactcaggtgactatatctgtgacactggagaacgccaaagctttgcatatctggaagtt aaggcactgccagttcttttcaaatcatctctgaaagatttggagagtgaagctggggaa aatgcagtttttcgatgtgaacttgacaaagctggagccaaagtcatctggaggaaagac aagagtgtaatagaagcaagcaaaaaatatcagctgaagcaagatggggctgttgctgag cttatcatttacaagctgcaaggaggagatgctggagactactgctgtgaaacagaacat gatcggacatctgctaaacttgctgtaaaggaacctgatatcataatcttaactggcttg aagagctgcatagtcaatgaaggcgaggacgttcatttcgaatgcattgtttctcatgat aatgcactcattgttcagtggacgctgcaagatgttccactacagaacaatgaaaggaat gaaatccgaatggaaggcaaaaggcacacacttacactaagaagtgtcacacagaaagac tcgggcacggtgtccttccatgttggtgcacacacttcttttgcttgtcttacagttaaa gcaatccctgtgctatcgtttgtgaaggagttaacaagccaggaagtcacagagggaggc agtgcttcattatgttgtgaaacttcaatccctgattccagtgtgacctggaagaagggc actcaggtcctatctgatggaaagaagtattccataaagaagaatggcacattccaaact ttagaaatctataagctatcagtggacgatggtggcgagtacatatgtgaagtgggagac aaacaaagcaaagctacattgaccgtcaaagaatgtgtaaaaatcacaagagaattaaag gatgtgactgtgataacgggcgaggatgctatcttccagtgtgaggtatcccatacaggg gttacgaatgttgaatggtggctcggctccaaccaccttcaaaacaatgacttaaatcaa atcagctgcagagggagggaacacagcctagtgctgaaaatggtcacacccgatgattca ggtgatgtagcgtttgtggttggccctcagaagagcatcgcctacttgttggtgcaggag aaacccaaagtcatattcttagagaagcctctggacttaactgccaaagagggtcaaaca gtcacactgtcctgcatgacctctgaccctgaggcctctgttacctggtacaaagatgaa gtgatgataaaggcaggtggacgctatctgctctacaaggatagagctgtccatcagctt cgcatccttagggtggaggaaggagatgcagggctgtatacatgcaaaaccaaagatgca gaaagctgcgccacccttactgttaaaggtcaacctgcatacttccggaaggagttagag aaccagaatgcaatagagggagatagtatcaccttgctttgtgaactctctaagccggtt aaaagtatagagtggagaaagggtggagtggtgctccaacccagtaagaaatttgagatg aaacaggaaggttgtgtgctggagctccatgtccataatctggaatcagaggacaatggc tactacacttgtgatgctggagcccagttaaccacagcatcactcactgtgcaagaggct gaggttctcatagtatcgggtataaagaatatagatgtgtatgtgggcgaacaggcaatt ttctcctgccagctctctcgccgtgccaaaggcagagttcagtggtggctaaatggcact cgtttggagaacagtaccttcagtgaaataagtgtgggtgaagaccatgtctacactctc actctaaggaacctttctcccaattattcgggtacagtcctgttcaaaacaggtggtctg acgtcttccgccaagctgttagtgaaagctaaaccaattgatattctccaagagctgagt aatgtggagaccattaatggcggggaggcactttttgaatgctccttgtctcgtcctgaa accaaagactgccggtggttaattgatggcaagcctgtgaaggagtctgcaaaagtggag attgtttcgtttgagagtggcagacgccatcttctgcttttaaaggacttgcatccctgt gaaaacacaagggttacattccaagctggtgcttcatcaactactgctcttctgtctgtc aaagcttggcaactggaggtggtcaagcctttggaagataagaccggcattgcaggagag caagttgagttcacttgtgtattgaatgaatctgtgcctgagactgaagtgacttggtat gcaaatggtgttgagcttcaatgtaatgaccaatgggccatgaaagccagtggctcttcc tacagcctaattttgaagaaagcccaggctcagctcacacaggaaatcacatttgcagct cggaatgccttatcgatggccaaactcatcacaatatctgtgcctgatccccctgaagac ccagagttggttagtaaaggcccaacattcgtcaccttgtcttggttcacacccctcagt gatggaggaagcccaatcattggatatcgtgtggaaatgcgtctggttgacagtatcctc tggctgccctgccacacagaaccagtgtgcaacactgaatttctggttgaaaacctcata cctggggcaggttacaggttcagagtggcagccattaaccgtgctggtattggagagcct gtacagctgcctcaaaccgtgacacttgatgcaccagtgaccatgaccaaaatgttaagc agctctaagatccaaaaaggaaagatggttcgtttagagtgtgagctttctacagagacc aaatcagtcacatggttcaaggacaacagagagatagagtttggagtcaagtaccaaatg gtagcagaaggaaagagccaagttttgctcataaaggatttccagtctacagaccagggt gtctattcttgtgtagcctcagaagaggcaaagacttcaatcaaccttaacctcgaagga gatgacacaacactttctcaggatgagggcagccagcccaaattgccccctgaggctgct tccgagggagatttacatgctctatgggatgcagtggccaagaagaggagaatgagtcga gagcccacattagattcaatttcagagttgccagaagaagatggaaaggaaaaggcccag agcaaagaaggaaaaggaaaaaaggaaaagcaagtgagacctgttgagccacctcccaag atcacagcagagcctaatctctatacaagttctgatgaggaatctctcagtgggacaact agcttgatgtcttaccttaagaaaagcagcaagtcctctgtgactgagactactgcctcc acgaaactgtatgagcacttccagatgactgagcaatctgttacaaagacatctgtagag cccctcatggaagctccgaaaggggatgagttgctagaggctgctgtcaaaattcaggca gccttcaaaggttataaagccaggaaggacatgagaccagtcttcaaagaagtatttaag gatcagtctaaggagcccaatgggacaattcatcttgagtgcattgtggagggtaagccg gataaagttcgctggctgaaagatggtgaacccttaacagatggcaagcaccatcacatt gacatctataatgatggcacctgctctctggtagtgactgctgccacaaccaaagacact ggtgtatatacttgtgaagtaaccaataagtttggtgtttccacccatagtggaaaagtc actgtagggacactgcgggaatcttctgggcgacgccccctcactcttggctacagtgca gatagtgaagctgagagctcctcagggagtgagatggatgagactttacgccaagcgagt aaacgattaaggcgacttctacgtactcacctccctccagatgtggaagaggaatctttt gttagtgcggatgaaggagatttaccgccaccagctctacagacttatagggaggatgat cagtatatctacatccgctttgataaccgtgcagaagctcaagtagcttcccagcgcttc caggaaatgtttacttatcaaggagttcccatcgaaacggccatcatagcagcagcaggt actaaggtagagttgcgtatcacaaagatgggtctctcccaagatggctccaaaacccca actcaggaccaaccaatgcctgctttcatgacaggagcccctgcggcccccatcatcctg acggagctccgtagccaagatgttcctgatgggtttccagtcagttttgactgtgtaatt gtcggcaacccccctcccactgtgagatggttcaaggatggaaagatgttggaggaaaat gaccattacatgatcaacgaagaccaggaaggccatcaccagctgatcatcacagctgtg ctgcccacagacatgggcgtgtaccgatgcatggctgaaaatgacagtgccatcgcctcc agcaaggctgagctgagggtggacatgtcttgcagttcagactatgacacagcagctgat gccacagagacgtcttcctatgtcagtgctaaaggttatgtgtctagctcggagcacagg gacacagaggcttttgagtctgtggcagaggacgagcagcttcctcagattttggatgag ttacatgatttattcctcagtcctggagcacccattgccaaaatgagtgtcagggtcaaa ggatttccaacaccaagggtttactggttcaaagacggcaccccactccaaggctccagc agaattgtattgtcgaccaaacgcgatcaacacagtcttgagattttggatgttaagcgt gaggacaccggagaatactcagcatatattagcaatatagctggctctgcctactcttca gcaagattgaatgtacaagctcctggagagcgtccagcacctgtacagagacgaatgaga gattcaaaggtgccacttgtgccaccacgcttcctagagagattcagcaacaagaaggtg aaacagggagcaagtataacgctgtcagtcaaagtggaaggctccccaaccccatctgta aactggttaaaggaagtgtcagataaggatgttctttggatcaaagcagacacaccaggt tacaaggtggccagctctggccgtcaacatagtctcatcctcatggaagtgggaaaaaaa catggcggcatgtacacttgcattgccaccaacctcgctggacagtcagtcaacacagcc cgactggacgtggagacagcaccagagcaaaagaaagtgggtccagaggttctgggaatt actatcagcccaccagaggaacagggcaaaggagagatcaaactaccttccatgggtgaa gtgggtactgatgaattcttacaaaaactcacaacccaaatcactgaaatggtatctgcc aggattactcaagcttcattgcgtgtcccaggagctgatgatgacgatgatgaatcaaaa accccatccccatctccacatcatggccgatcacgccctccatctctgatcgcagactct tcatctgagtctgatgaaggagatgccaggggagagatgtttgaaatctacgtggtgacc gctgactacaaccccatgggggtcagtaaagatgccatcgctctgaaggagggccagtat gtggaggttctggactctgcccatccacttaaatggctggtccgcaccaagcccacaaaa tcccacccatctcgccagggatgggtctcgcctgcatacctcgacaaaagactgaagctg tctgcagacatagcagacctcccagagacctccagagaagaagtctcagagacggagtac aagaagaaactctgtcaacttgtccaagagctgatcaacacagaaactgagtttctgaag cagatggagttcttcacttcacaccatctgaagcatgtggaggagcagagcacaccacct gaaatcaccagccagaaggaaaccatcttccgtaatatcaatgatttgaaatccttccac agcagctctctgctacctggcctgcaagattgtgacacagatgatgacattgccatgcat ttcctgagaaactctgaagggtttgagaaatatctgcagtacttcattggacaactgcaa gctgagtcagccatcagtgagaaagaagtgcaccagtatttcaaggattatacagcctca gagttggcaaatgttgacccctcagaaggtccagtgctaagcatcaatgcttaccttcag agaccaccagagagaattcagaagtacagggctttactgaaggaattgatccggaataaa gcgaggaacggtcagaactgctgtttgttggagcaagcctatgccatggtgtcgtccctc tcccagcgctcagaaaacacacaccatgtatctctcatagagagctaccccgccaatctg gaggcgctgggagaacctataagacaggggccttttattgtttgggaaggagctcctgga attcgaacatcttccagaggtcaccaccgccacgtcttcctcttcaaaaaccatgtggtc atctgcaaacagaagagagacactaatacagacactcaggcatatgtgttcaagaatatg atgaagctcacaaacattgatgtgaacgagaccgttgagggtgacgagagagtgtttgag atctggcatgagcgcgaggactctgtgagaaaatacacattgcaggcacggactgttatc atcaagaactcctggctccgtgacctccgtgacctccagctgcgctacagcatgccagcc tggagctctccagattttgactcagttttgacagactacacagcggagctcggacagaca gtaaagctcgcctgcaaggtgactggtgcccccaaaccacaggtcacctggtacaaagac ggacatgccgtggaagcagatcctcatcacatcatcattgaggacccagacggctcttgc acactcattttggacaacatgacggcagacgactcgggacaatacatgtgctttgccacc agctctgcgggcaacgccagcacactaggcaaaatcactgtgcaggtacctccacgtttt gtgaataagatccggaacgccacactttatccaggagaagatgctcagttcacctgcacc atccagagcgcaccaagtcccaagataagatggtttaaggatggtaaactgctgacagac caggagaagtttcagacatacagtgaagcgtgcagtggggtgttggttctagttatcaag aaccctggagaacgagatcttggacactatgagtgtgagctgtcgaaccgtctgggcagt gccaggtgtgccacgcagctgatcactcctgctgtggcaatggcgcgagaacgtagagca aatcaggccatcagtatagaagtaacagaacaagagacaaaaatgccgaagaaaaccata attattgaggagacgatcaccacagtgatgaagaacacccgtacgaaacgacacccatcc ccgcgtccatcgcccaggggagctcactgctccgagacgtccacacccgaaccgcccaga cagagacgaaccctggccaggaagactgtaccgacgctgtacgttccagagcaggagggt gccacggccaggaacccaagatgggttgaagttgaggagacaatcgagtataaagtgaac aaatcacccaagcttccaagaagaagaggcgtctcccccagcaagttctcaccacctggc aatccaaacactaataactccaacaacaagttactagaagaggcaatgggtgccgcaatg gctctgcaagcttcttctgatacacatgaagaggaaactgcacagaatgtgttcgaagta ccttcagggatcgtaaatatgacaacattcgaaatgagtgacccgtgtgtctctgatgaa gaaactattatcgcggagcctgaagacgacgaacttgctgctcgagattgcaaaatgctg actgacgggaatcgagttcttactcttgaagatcttgaggactacgtccctcaggcaggt gaaacgttcagcagcggtacagaccatcacatctccgtcgagaagccaagtgagatctcg gtgttgcagagagaaattaacgagtctgttattggcaaacccattgtgctgaacgtggta cgtccggtgccaccggcaaaacctcgcaagggattatttggctccttcaaggaacagatt tccagcatgtttagtccaggtttatcggcgggtgtcagctcgcaggcaaggcgagagaag attatacctattcatgtgacgggagaaccttcatccaactattcacgccataccagtagc tttgcaaagcttgaagtccagtcgatgtactgctccgtgctccagagagaaaaggaggga ggtctgcagagcttcaaaacacaggtttccacacaaacccgcaactacacacccaccgga caggtcactcttcagatcagcaagaagcagccatttgaaaatcagtaa

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