Cottoperca gobio: 115022514 Help Entry 115022514         CDS       T07513                                  Symbol obscn Name (RefSeq) LOW QUALITY PROTEIN: obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism cgob  Cottoperca gobio Pathway cgob04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cgob00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     115022514 (obscn)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cgob01001]     115022514 (obscn)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cgob04131]     115022514 (obscn) Enzymes [BR:cgob01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      115022514 (obscn) Protein kinases [BR:cgob01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    115022514 (obscn) Membrane trafficking [BR:cgob04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     115022514 (obscn) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 Ig_5 Ig_6 Izumo-Ig V-set_CD47 fn3 C1-set C2-set_2 RhoGEF Adeno_E3_CR1 PH IQ Receptor_2B4 Motif Other DBs NCBI-GeneID:  115022514 NCBI-ProteinID:  XP_029309374 UniProt:  A0A6J2RGW7 LinkDB All DBs Position 17:complement(8952554..9010585) Genome browser AA seq 6624 aa AA seqDB search MDQNLFGGVPRFLTRPKAFSVCVGKDATLSCTIVGSPTPLITWEKEKLKLTSGERFKTVE DGDVYRLTIYDLTLEDSGQFMCRAKNSVGEAYAAVTLKVALPSEMAQRAPSFMVKPTSTR VGLGGDVVFYCRVVAYPDPNFDWEKDGRYLGESMRIKIVSDSDSSTLKIQSVRNLDSGTY TCRAQNTVGRSHAAAALVVDAQDSRNLAADKNTSLLSHLQKRKEEMNKDISIYRTEESRS SGSSSTKAKITDSMSSLSLEYELRASALAKLPKGVFTRTCTVTEGKHAKLSCFVTGHPKP HIIWRKDGANISEGRRHVIYEDQAENFILKILYCKQVDNGLYTCNATNMAGQTYSAVLVT VKEPKVPFRRKLQDVEVQEKTSATLMCEVPVSATHANWFMEETRLDQSTKYFMEQEGTLR RLTIHNVTTNDDGVYICEMKEGSRTVAELTVLGNITKKLPRRTVVPVSDTVIFCVELEHP FPDVYWTRNSEKLKEDSRISIACVLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFSALA ARKHPPDPPVDAVVLNKTDSSVTIRWSPPDSDRPVPIKGYIVERKKVGTQTWQRCNAGET IISTEINFCSATEESTYQFRISAMNDFGQSPYLEVPGSFYLEPSAEIRKGLINSTAFSGE EFSISLELSAVCSGFWSLNGRLLRSGADYLITKSKSTHTLLIRDVTMDMNGTEVKFVGGG SQSSCILSVKAAPVRFTNKSALLEAVICSAQATAQLTAEVSSYDAQVVWMRNGREVKMGK KYEYMIMDRKRILIVHNVTEEDVGIYECVLADDRVSLQLSLKDEPAKFLNKARGTMGMSS SLKGDLELSCEVSPASAVVVWRKDQVEITEDQRTTTVSKGTQRKLIIKNAKKSDEGHYSC DTAADKVTFQVKIKETQAVAAFSNKDSVQKEVKATVSQKATLSCDVLDSKAEVKWYKDGK LLISSRTIYSEVKGSTRQLVIEKVEKSDAGEYTCNAGGDKLVFNILVSEFQSAFSNKDSV QKEVKATLSQKATLSCDVLDSKAEVKWYKDGKLLISSRTIYSEVKGSTRQLVIEKVEKSD AGEYTCNAGGDKLVFKILVSEFQSAFSNKDSVQKEVKATLSQKATLSCELADTKTEVKWY KDGKLMTSSKTIHTETKGKSRQLVIDSVEKKDAGEYTCEAGTEKLAFKMHVAEAQSAFSN KESVQKEVKATLSQKATLSCELADTKTEVKWYKDGKLMTSSKTIHTETKGKSRQLVIDSV EKKDAGEYTCEAGTEKLVFKLKVADTQSALSTIESVQKEMKATVSQKATLSWEVSDSKTE VKWYKDGNLICTSKAIHAESKGKSRQLVIDSVEKNDAGEYMCEAGSEKLLFKIQVDGAST EGQAKSTFLNKESVQKEVKATLSQKSTLSCEVADTKTEVKWYKDGKLMTSSKAIHMESKG NMRQLVIDSVEKKDAAEYFCEVGTEKLAFKVQVTEIQAKSAFSNKESVQKEVKATLSQKA TLSCELADTKTEVKWYKDGKLMTSSKTIHTETKGKSRQLVIDSVEKKDAGEYTCEAGTEK LAFKMHVAEAQSAFSNKESVQKEVKATLSQKATLSCELADTKTEVKWYKDGKLMTSSKTI HTETKGKSRQLVIDSVEKKDAGEYTCEAGTEKLAFKIQVAEAPAGFSNKESVQKEVKASL SQKATLSCEVSDTKVEVKWYKDGKLLTSSKAVHMELKGKSRELVIEKMEKKDAGEYTCEA GTEKLAFKLQMTDAAVKFQKNLVKDTCIVQASEKVVLTTELTTESGSVKWCRDGVELKES SKYEMKKDGLSRTLIVKSSESKDSGTYSCQTADDKLEFKVQVKDSALKFVVPLKPATVEL EGTLSLMCELNQASGDVVWQHDGREIKPGGRHCVRTDGAKRVLTVSGMTKEDEGEYSCEC RNDKTSAKVSSKAPRLVRLTTKLNNVAAMEGKDAIFKCAVNPADVNVKWFHNNTPVTAGP KYKIGRGGSSHSLTITSVTQKDAGEISVDAEGKSCKATLQVQHEPVTFKKKIENLTVEEQ SEVKLEVELSKPSDEVRWMKNSVVLQASGNMEIRVDGAKQALVFKSVTYADRGIYSCETL EDKTQAKLNVEMKKIQVIKGLTETKAHETETVTLEVELSQADVEGSWTRDGAKLKSGANY RITALGKKHALTLSNLKREDAGTIVFQAEGVHISAKLIVTEPPAMISKPLMDNSVPDKEK VTFECEVSRTNADVKWFKNDVELKPGKNYGIHSLGRKRSLVINKCTPEDAGTYICRTTDD NTAAKLTVHAREVKIVKKLEDVEVMEKESAAFVCEISHDEVDCQWHKGSIKLKAGDNIKM RQEGRTYVLLFKSVTPEDMGEIKFTADKASSAAKLKVKELPVKFVKRLRDKIAMYKHRGH LECQVSRVSANVKWYKNKLEIKQGKKYDIKSEDVYRKLTINDVDSGDEDTYTCDGTDDKT SCKLLVEEQSISIVRELSSVEVTEPFAAVFEVEISMELVKPPIWTLNGVAVQESADVEME KEGTMHRLTFKKTKAAMAGPVQFTAGKSKSLAQLTVKERPLEIAEPIKGVKAKEKSSAIL TCKFSASPKEVTWFKGQVLLATSGKYNIKQDATRAQLTIQTLTEEDSGEYRCQSGPAETK GTLTVEVREIKITKHLADTEVDEDSDAVFTCEINYADEEVQWLLNDKVLFTNEVNTISHE GKVHKLTLKNLAPQDGGTISFQVRKVKESVTLKVKEKRAVFLKSLDDVIGEEKGMITLAC EASKPRVSPTWRKEGKVLKAGSKYELLHTGKSLGLIIKDVTKEDAGEYSCDLGTEVSKTK VTVREIGIGITKWLKSAEANEGETCNFECILSRESTDECSWTLNGHTITNGGRFKVTSKG RKYMLTIKDVTPADTGEVVFNIKDLNSKTTLTVEGKASSVSKGLQNVSAVQGEDAVFTCE VTQANSTIHWAMEGKAIKKSQKYDISKEDKVMKLTIHNVSAQDSGEYSCEVVGGATTKGK LEIKEPIHKFTKALKDSEAEEKSSVTLQCETAQTPSTVIWLKGHTELKAGGRYEMSHKVG VLTLTIKDLEEKDTDIYTCDVGTAKNMAKVTVKALPANFKEKLKNQEKKEEETVTLCCRL SKPVDGVQWKKDSEILKVGVKYEMKMEDTSCELQIKNLVVEDSGEYSCECGDQKTSATVK VNALPPTFKQKLESQEAVEGASVTLHCEISKPGVPVEWKKGTQVLKSGEKYQMKQKASVN ELLINKVVPDDSGDYSCVCGDQKTTASVNIKAQPVTFKQKLETQEAVEGADIVLLCEISK PGVAVEWKKGTQVLKSGEKYQMKQKASVNELLINKVVLEDSGDYSCVCGDQKTTASVNIK AQPVTFKQKLETQEAVEGASVTLHCEISKPGVPVEWKKGTQVLKSGEKYQMKQKASVNEL LINKVVPEDSGDYSCVCGDQKTTANIKIKVLPVTVIQDLDSQEAEEGDSVTLHCELSKPG LRVEWKKETQVLSCGEKYQMKQTRFSYELQIFDLRPGDTGSYSCCSEDTISSASLAVNAA PVVFTKQLESQTADECDSVTLHCELSKPGVPLEWRKGELGLCPCAKYEIRQTEHLALLVI HDVDPEDAGSYTCDTGDRQSTAHLAVKGMLAKTCCLWWRYLSCKLINYLLFKLSIKNTFG IXHDLSVKTXGSLPPPLHTLVVXCVWQLSLRCPKCSLLISFTSSTAAQPVHFKTKLQNIE RQEGESASLRCETTKPGASVVWRCGDRVLASSSKYHLKQEGTIVELVIYKLEGADSGEYS CDAGNKRTSAVLTVQEVEVKILKFLESCLVYEGEDVRFECRVSREEAPLAQWKLQDVPLQ NNEMNLIKSEGRVHSLTLRGVTAADSGTVTFTVGNHTSTASLTVRAAPVLFKKELESQEA TEGDKATLSCETSSADCKVVWLKDSTVLTHGEKYSMEQTATTHSLVILQLNMKDSGEYTC DTGDKKSTATLTVKEHVRLTRELCDMTVPTGQDAVFEVELSHSGVTNGEWWLGDNLLQNN DLNQMSSQGRVHRLTLKMVTTDESGDVAFVLGEEKTVACLLVEEKPKVLILEKPHNTVAV EGETVSLACTISDAKATFTWMRNKVAIQAGLKYDLRNNGAFHQLRIHNVVPEDSGTYTCD TGDAQCDVTLTVEGAPVFFHKELKNHDAIEGDDVTLRCELSKPGVRVEWRKGGMVLLPGK KCEMRQEGCIQELCIWNLEPEDSGYYTCDAGDQLTTASLAVQVKEVFIVSGLKTTDVFVG EWATFSCQLSGRAPEKVQWWLDGTLLENSPFSEIGLSQGNIHTLSLKNLATDDSGTVTFE AGSVTSTAKLLVKDPTVEVVNEMEDLRVLENQPAEFICQFSRPVKAQWKKDGQPLQPDGR RVVVEQDWNVARLYISRVSAEDRGTYSCEAELACAVASLYVEGKPIDIVQGLENVETFDG GEVLLECALSRPESKDCCWLFDGKPVKESRNAEIVTFESGRRHLLLLKELRVKDSCTVTF KAGKASTSAQLSVKRWQLDVVKALEDTVAAVGEKVEFCVELTEPVPTAEVAWYANGIELK PNDLWATRADGCSYRLVLRKAPLLPQQEITFAARDALSLAKLTIITVPDPPEDAEVLSKT EKSVTLSWFTPLHDGGSPILGYRLEMRLVDSSLWLPCQSEPVCNTEFVVENLIPGSSYRF RVAATNRAGIGEPVELPQTVRLDTPMQPPISPGIEAKQVEAEMMGQPSLPPEAAEEGDVH ELWEESAKKRRMSREPTLDSITEQPEDDGKGGQKKSGQIELKASEKVEIKSGEKEQVIVS KKQTESKLYTSSENESVSGGSTLVSYLKKSSTSTVTATNEAQTMTTERFFAHFQKADQKT VQQTKVETSTIQQTDAKQVSTEETNIMEISKEDEPELRDAAIKIQAAFKGYKARRDMRPV FKEAFKDQTKEPNGTIHLECVAEGKPDKVRWLKDGESLTDGKHHHIDIYNDGTCSLVITA ITTKDTGVYTCEVTNKFGVTSHSGKVTVGTVRESSGRRPLTVGYSADSEPDSSSGSEMDE SLRQASKRLRRLLRTSLPPNVEEELFVSADEGDLGPPDPHSYREDDCYIYIRFESRTEAE VASKRFQEMFTIHGVPVETTILDSGPLKVELRIRKMGYTQDGTQTPTPDRQPPAFMAGAQ AAPVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGCHQ LIITTVLPTDMGVYRCTAENSSGITATKAELRVDMSCSSDYDTAADATETSSYVSAKGYL SRETETFESVAEDDQLPQVVDELHDVHVCPGSPIAKLQLKLKGFPKPRIYWFKDGHPLRP SERILLITERDVHGVEILEVKKEDMGEYSAYISNAAGSAYSSARLIVLRPGEIMPQDKRD PKEPLVPPRFIERFSNRKVKQGSSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGY KIASSGRQHSLILMDVGTEYTGAYTCIATNKAGQSICTAHLEVDDVPQQKKETNASEVFG FTISPPDEEAGRGKESKLPYLGEVGTEEFLMKLTSQITEMVSAKFTQDSLQNHEVLQWMK SWPKTTTSLRVPGVDSDDETKTPSPSPHHGRSRPPSLIADSSSESDEGDARGEMFDIYVA TADYTPTISIKESISLKEGQYVEVLDSAHPLKWLVRTKPTKTTPSRQGWVSPAYLDKKLK LSADTSDLPETNEEEVSEGEYKRKLFQLVQDLINGESEFVKEVDFFTSHHVKHADSPDAP PDVSSQKEAIFRNIDDIKSFHSKAFLPKLNDCETDDDVAMCFLKNKEGFEKYLEYLVGQS KAESAVNDKAVHRFFKEYTEKVQAGADPADPPVHSINASLQHPLERIQKYKAVLKELIRN KAKNGQNCCLLEEAYAMVSALPQRSENTHHVSMIENYPATLEVLGEPMRQGPFQVWEGAP GIRTSSRGHHRHVFLFKNYCIICKPKRDSNTDTQAYVFKNMMKLNNIDVNETVEGDDRAF EIWHEREDSVRKYTLQARTITIKNSWLRDFRELQQRYSMPTWSPPDFDEILANCTAELGQ TVKLACKVTGLPKPAVTWYKDGRTVEADPHHIVIEDPDGSCTLILDNMTADDSGQYMCFA TSSAGNASTLGKITVQVPPRFVNKMRNAIFVAAEDAQFTCVIQSAPNPKIRWFKDGRLLT DQEKYQTFSELRSGVLVLVIKNLTERDLGHYECELSNRLGNAKCAADLVPPSAVTRTGEQ AITIEVTEQETRIPRKTIIIEETITTVVKNPRMRRHKSPGLTVAGAYRSETSTPEPPTAR LRRMPTPRKTTIPTLYVSQPEGAEARAMESRPTWVEVEEVIEYKVNKSPRLPRRRGISPA LSDRAAAPSRSKRSPPENPNTNNCNNKLVEQAQLQGDVSSSPLSWEEEEGNVSSDSVTGE PHELSSVLTPAAEDSDDLDDEQTVIFEPDDEDDDSLGDQEPKILTQGGRVLTLEDLEDYV PEEGETYGSSSAPAAEKPCEISVLQREIGGSTVGQPVLLNVGRPVVVPRQRSGFFGRFRE HLSSSLFTSAAPQASGARSRTERHVPIQVSHAKMEVKPSYCSEVQRVECGQQSFKTKVST QTYGYTSVGNPVTLQISDNLYQNQ NT seq 19875 nt NT seq  +upstreamnt  +downstreamnt atggatcaaaacttgttcggaggagtcccacgattcctcacccgcccaaaggcattctca gtgtgtgtaggcaaggatgccacacttagctgcactatcgtgggcagcccgaccccactg ataacctgggaaaaagagaagctgaagctgacttctggggaacgcttcaagaccgtggag gatggagatgtgtaccgcctgaccatctatgatttaacactggaggacagtggccaattc atgtgccgagccaaaaacagcgttggggaagcttacgctgctgtgaccctcaaagtggcc ctgccatcagagatggctcagagggccccttctttcatggttaagcctacctctacacgt gtaggtttgggaggcgatgttgttttctactgccgggttgtagcttacccagatcccaac tttgattgggagaaagatgggcgctacttaggggagtctatgcgtatcaagattgtttcc gacagtgacagcagcaccttaaagattcaaagtgtgcgtaacctggacagcggcacctac acctgcagggcccagaacaccgttggccgttcacatgctgcagcagctcttgttgtcgat gcccaggattcccgcaacctggctgcagacaagaacacctccctcctctctcacctacaa aagcgcaaggaggaaatgaacaaggacatctctatctatcgcactgaagaaagcagatcc tctggttcttcctccaccaaggccaagatcacagatagtatgagttctctgagtctggaa tatgagctgagggcatctgcgctggcaaagctgcccaaaggtgtgttcacccgtacctgc acggtgactgaaggcaagcatgccaaactcagctgctttgtgacgggtcaccccaaaccc cacattatctggaggaaggatggagcgaacatcagcgagggccgcaggcatgtcatttat gaggaccaagctgagaacttcatcctcaagatcctgtactgcaagcaggttgataatggt ctctacacctgcaatgcaaccaatatggctgggcagacctacagtgcagtgttggtaaca gtcaaagagcctaaagtgccattcaggaggaagctgcaggatgtggaggtacaagagaaa acgtcagccaccctgatgtgcgaggtgcctgttagtgccacccacgccaactggttcatg gaggaaacgaggctggatcaaagtaccaagtatttcatggagcaggaaggcaccctgcgt cgtctcaccatacacaatgtcaccaccaacgacgatggtgtttacatctgcgagatgaaa gagggcagtcgcactgtggctgagctcactgtcctgggcaacattactaagaagcttccc cggaggacagtggtccctgtcagtgacactgtcatcttctgtgtggagctggagcatcct ttcccagatgtctactggacccgcaatagcgagaagctgaaggaagattcccgtatttcg atcgcctgcgtgctcagacagtacacactcacgattagagattgccaggcagatgactca ggagaagtggcgtttgtggctggagactgcaagacttccacgcgattttctgctctagcg gcaaggaagcatcctcccgatcccccagttgatgcagtggtgctgaacaagactgactca tccgtcaccattcggtggtctcctcctgacagcgaccgccctgtccccatcaagggctac atcgtggagaggaagaaggttggcactcagacatggcagaggtgcaacgctggagaaacc atcatatcaacagagatcaacttctgcagcgccacagaagaatccacctaccagttccgt atctctgctatgaatgactttggccagagtccctacctggaggtgcctggaagcttctac ctagaacccagtgcagaaatcaggaaaggcctgatcaacagcactgcattctctggtgag gagttttctatctccttggagctgtctgctgtttgttccggcttctggtctctaaatggc cgcctcctgcgcagcggagccgactacctcatcaccaagtccaagagcacacacactctg ctcatccgtgatgtgaccatggatatgaacggaactgaggtcaagtttgtgggtggtgga tcgcaaagcagttgcatcctatctgtaaaggctgctcctgttaggttcaccaacaagtca gctctgctggaggcggtgatctgcagtgcccaagctactgctcagttgactgctgaggtg tcgagttacgatgcacaggtggtttggatgaggaatgggcgggaggtgaaaatgggaaag aagtacgaatatatgattatggaccgcaagaggatccttatagtacacaatgttacagag gaagatgtgggcatctacgagtgtgttttagctgatgacagagtgtccctgcaactctct cttaaagatgaacctgccaagtttctgaacaaagccagaggtaccatgggaatgtcatca tcccttaaaggagatcttgagctgagctgtgaggtatctcctgccagcgcggtcgttgtg tggagaaaagatcaagtggagatcactgaggaccaaagaacgaccaccgtctccaaaggg actcaaagaaaactcatcatcaagaatgccaagaaaagtgacgaaggacattactcctgt gacacagcagcagacaaagtcacattccaggtcaagataaaagaaactcaagcagtagct gccttctctaacaaggactcagtccagaaggaagtcaaagctactgtctcccagaaagcc actcttagttgcgatgttttggatagcaaggcagaggtgaaatggtataaagacggcaag ttgttgatatccagtaggacgatatactcagaagtaaaaggcagtactcgtcagctggtg attgaaaaggtggagaagagcgatgctggagagtatacatgcaacgctggaggggataaa ctggtcttcaacatattagtgtcagagttccagtcagctttctctaacaaggactcagtc cagaaggaggtcaaagctactctctcccagaaagccactcttagttgcgatgttttggat agcaaggcagaggtgaaatggtataaagacggcaagttgttgatatccagtaggacgata tactcagaagtaaaaggcagtactcgtcagctggtgattgaaaaggtggagaagagcgat gctggagagtacacatgcaacgctggaggggataaactggtcttcaagatattagtgtca gagttccaatcagctttctccaacaaggactcagtccagaaggaggtgaaagccactctc tcccagaaagccactctgagctgtgagctagcggacaccaaaacagaggtgaagtggtac aaggatggcaaactgatgacttccagcaagacaatccacactgagacgaaggggaaaagt cgtcagctggtgatcgacagcgtggagaagaaggacgctggagagtacacctgtgaggct gggactgagaagctggcttttaagatgcatgtagcagaggcccagtcagccttctccaac aaggagtcagtccagaaggaggtgaaggccactctctcccagaaagccactctgagctgt gagctagctgataccaagacagaggtgaagtggtacaaggatggcaaactgatgacttcc agcaagacaatccacactgagacgaaggggaaaagtcgtcagctggtgatcgacagcgtg gagaagaaggatgctggagagtacacctgtgaggctgggactgagaagctggtcttcaaa ctcaaggtggcagacacacagtctgcactctctaccatagagtcagtccaaaaggagatg aaagctactgtctcccagaaagccactctgagctgggaggtatctgattccaagaccgag gtaaaatggtacaaggatggcaatttgatatgcaccagtaaggcaatccatgcagagtcg aagggcaagagtcgccagctggtgattgacagcgtggagaagaatgatgctggagagtac atgtgtgaggctgggtctgagaagctgctctttaaaatacaagtggatggcgcttctaca gaaggccaggctaaatccactttcctcaacaaggagtctgtccagaaggaggtgaaggcc actctctcccagaaatctactctgagctgtgaggtagctgataccaagacagaggtgaag tggtacaaggatggcaaactgatgacttccagcaaagcgatccacatggagtcaaagggc aatatgcgtcagctggtgatcgacagcgtggagaagaaagatgcagcagaatacttctgt gaagtcggaactgaaaaactggcatttaaagtacaagtgacagagatccaagccaagtca gctttctccaacaaggagtcagtccagaaggaggtgaaagccactctctcccagaaagct actctgagctgtgagctagctgataccaagacagaggtgaagtggtacaaggatggcaaa ctgatgacttccagcaagacaatccacactgagacgaaggggaaaagtcgtcagctggtg atcgacagcgtggagaagaaggacgctggagagtacacctgtgaggctgggactgagaag ctggcttttaagatgcatgtggcagaggcccagtcagccttctccaacaaggagtcagtc cagaaggaggtgaaagctactctctcccagaaagccactctgagctgtgagctagctgat accaagacagaggtgaagtggtacaaggatggcaaactgatgacttccagcaagacaatc cacactgagacgaaggggaaaagtcgtcagctggtgatcgacagcgtggagaagaaggac gctggagagtacacctgtgaggctgggactgagaagctggcttttaagatacaggtggca gaagccccagctggcttctctaacaaggagtcagttcagaaggaggtgaaagcctctctt tcccagaaagccactctgagctgtgaggtttctgataccaaggtggaggtgaagtggtac aaggatggcaaactgctgacttccagcaaagcagtccacatggagttaaagggcaagagt cgtgagctggtgatagaaaagatggagaaaaaagatgctggagagtacacttgtgaggct ggaacagagaagttggcatttaagctgcagatgacagatgcagctgtgaagttccagaaa aaccttgtcaaggacacatgtattgttcaagcaagtgaaaaagtagttttgactaccgag ctgaccaccgagagtggtagtgtgaagtggtgtagagatggtgtggagctcaaggagagc agcaagtatgaaatgaaaaaagatggcctttcccgtaccctgattgtaaaatcatccgaa tccaaagacagtggaacatactcctgtcaaactgctgatgacaaactggagttcaaagtt caagttaaagattcagctttaaagttcgttgtccccttgaaacctgctacagtggagttg gaaggtacacttagcctgatgtgtgaactaaatcaagcctcaggggatgttgtctggcag catgatggccgtgagattaaacctggaggcaggcactgtgtcaggacagatggtgctaag cgggttctcactgtgagtggcatgactaaagaagatgaaggagaatacagctgtgagtgt agaaatgacaagacctctgctaaagtctcctcaaaagcacccagactggtgaggctcacc actaaactgaataatgtggctgcaatggagggaaaagacgccattttcaagtgcgctgtc aacccagcggacgtcaacgttaaatggttccataacaatacacccgtcactgctgggccc aagtataagattgggcgtggtggcagcagtcactcactcaccatcacctctgttacccaa aaagatgctggagagattagcgttgatgcagaaggcaaaagctgcaaagctacactgcaa gtgcagcatgaacctgtgacatttaagaaaaagatagaaaacctgacagtggaggagcag agtgaagtgaagctggaggtggagctcagtaagccatccgatgaagtgaggtggatgaag aacagtgtagtgctgcaggcttcaggaaacatggagattcgggtagacggagctaagcag gctctggtcttcaagagcgtgacatatgctgaccggggcatctactcctgtgaaactctg gaggacaaaacacaggccaagctcaatgtggagatgaagaagatccaggtcataaagggt ctaacagaaaccaaagcacatgagacagagacggtaactcttgaggtagaactcagccag gcggatgttgaaggctcatggaccagggatggggccaagttaaagtcaggggcgaactac cgtatcacagccctgggaaagaagcacgccttaacgttgtccaatctcaagagggaggat gcaggaactattgtcttccaagcagaaggagtacatatttctgccaaactaattgtcaca gaacctcctgctatgatctccaagcccttgatggataacagtgttcctgacaaggagaag gttacttttgaatgtgaagtgtccagaaccaatgcagatgttaaatggttcaagaatgac gtggaactgaaaccagggaagaactatggcatccactccttgggccgaaagcgctctttg gtcatcaacaaatgcacccctgaagatgcaggcacttacatctgtcgcactactgatgac aacaccgccgccaagctcaccgttcatgccagagaggttaagattgttaagaagctggag gatgtggaagtgatggagaaggagagcgctgcgtttgtctgtgaaatatcacatgatgaa gtggactgccagtggcacaaaggaagtattaaactcaaagccggtgacaacatcaagatg agacaagagggcagaacctatgtactgctgtttaagtctgtcaccccagaagatatgggt gagattaaattcactgctgacaaggcttcttcggctgcaaaacttaaagtgaaagagctg cccgtcaagtttgtgaagagactcagggataagatagcgatgtataagcaccgtggtcat cttgaatgccaagtgtcacgtgtcagcgcaaatgtgaagtggtacaagaacaagctggag atcaaacaaggcaagaagtacgacatcaaaagtgaagacgtgtaccgaaaactcaccatc aacgatgtggactccggggacgaagacacctatacctgtgacggcactgatgacaagaca tcctgtaaactacttgtggaagagcagtccatcagcattgtgcgggagcttagttcagta gaagtgacagaaccctttgcagctgtttttgaagttgaaatcagtatggaactggtgaaa cctcctatttggactctgaatggagttgctgtgcaggagagtgctgatgttgaaatggag aaagagggcactatgcaccgtctcactttcaaaaagaccaaagcagcgatggcaggacct gtgcagtttacagctgggaagagtaaatctttagcccagctcacagtcaaagagcgtccg cttgagattgcagagcccatcaaaggtgtgaaggcaaaggagaaaagctctgctatactc acctgcaaattctctgcctcacccaaagaggttacttggttcaaaggccaggtgcttctg gccacgtcaggcaagtataatattaagcaagacgctacaagggctcaacttactattcaa acgttaaccgaggaagacagtggggagtaccgctgtcagtccggacctgctgagaccaaa gggacacttactgttgaagtgcgtgaaattaagatcaccaagcacttggctgacacagag gtggatgaagacagcgatgcagtgttcacatgtgagatcaactatgccgatgaagaggta cagtggcttctgaatgacaaggtgctcttcaccaatgaggtcaacaccatctctcatgaa ggaaaggttcacaagctcacactgaagaacttggcacctcaggatggggggactatcagc tttcaagtccgcaaggtgaaagagtcagtgacacttaaggttaaagaaaagcgcgctgtg ttcctcaagtctctggatgatgtcattggagaggagaaaggcatgataactctggcgtgc gaggcgtccaagccaagggtttctcccacgtggagaaaagaaggtaaagtcttgaaggcc ggatcaaagtacgagctccttcacacaggcaagtctttgggattgatcatcaaggacgtc accaaagaagatgctggagagtatagttgtgatcttggaactgaggtttctaaaacaaag gtcactgtaagagagattggcattggaattaccaaatggctgaagtcagctgaggcgaat gagggcgagacatgcaactttgagtgcatcttatctcgtgagagcacagatgagtgttcc tggactcttaacggacacactatcactaatggaggccgcttcaaagtcaccagtaaagga cgcaagtacatgctgaccattaaggacgtcactcccgctgataccggagaggtagtgttc aacattaaagacctgaattccaaaacaacgttaacagttgaaggcaaagcatcatctgtg tctaaaggactacagaatgtaagtgctgtccaaggggaagatgctgtttttacctgtgag gtaacacaagctaattccactatacattgggccatggaaggcaaagccatcaaaaagagc cagaagtatgacattagcaaagaggacaaggtcatgaagctgaccatccataatgtctct gctcaagactccggagagtacagttgtgaagttgttggaggtgcgaccactaaaggcaag ctggaaatcaaagagccaatccataaattcactaaagcgcttaaggacagcgaagctgag gagaagagctctgtgaccttgcaatgtgagactgcacaaaccccatccactgtgatatgg cttaaaggtcacacagagctcaaggctggaggtcgatatgagatgtcccataaggtgggg gtcttaactctcaccatcaaagacctggaggagaaagacactgatatctacacttgtgac gtgggcactgccaagaacatggcaaaggtgacagtcaaagccctgcctgccaattttaaa gaaaagctcaagaaccaggagaaaaaggaagaggaaaccgtgacactttgctgcaggtta tcgaagcctgtggacggtgttcagtggaaaaaagactctgaaattctcaaagttggcgtg aagtatgagatgaagatggaggacacttcttgtgagcttcagattaagaatttggtggtt gaagatagtggagagtattcttgcgagtgcggggaccagaagacatctgcaactgtgaaa gtcaatgcattgccgccgaccttcaagcagaagttggagagccaggaggctgtggaagga gcaagtgttacactgcattgtgagatctctaaacctggagtcccagttgagtggaagaag ggaacacaagtcctgaagtctggagagaagtaccagatgaagcagaaggcctcagtgaat gaactcctgatcaacaaagtggtgccggacgacagtggagactacagctgtgtgtgtgga gaccagaagaccacagcaagcgtcaacattaaggcccaaccagtgaccttcaaacagaag ttggagacccaggaggctgtggagggagctgacattgttctgctctgtgagatctccaaa cctggagtcgcagttgagtggaagaagggaacacaggtcctgaagtctggagagaagtac cagatgaagcagaaggcctcagtgaatgaactcctcatcaacaaagtggtgctggaagac agtggagactacagctgtgtgtgtggagaccagaagaccacagcaagcgtcaacattaag gcccaaccagtgaccttcaaacagaagttggagacccaggaggctgtggaaggagcaagt gttacactgcattgtgagatctctaaacctggagtccctgttgagtggaagaagggaaca caagtcctgaagtctggagagaagtaccagatgaagcagaaggcctcagtgaatgaactc ctaatcaacaaagtggtgccggaagacagtggagactacagctgtgtgtgtggagaccag aagaccacagcaaacatcaagatcaaggttcttccggtcacagtcattcaagacctggac agccaagaggctgaggagggagatagtgtcactctgcactgtgagctttcaaaaccggga ctccgtgtcgagtggaagaaggaaactcaagtcttgagttgtggagaaaagtaccaaatg aaacaaacaagattcagttatgagctacagatcttcgacttgagacctggagatacagga agctactcgtgctgttcagaggacacaataagctcagcctctcttgcagtgaatgctgcc ccagttgttttcacaaaacagcttgaaagccaaacggccgatgaatgtgacagtgtgacc ctgcactgtgagctttctaaacctggtgttcctttggagtggaggaaaggagaacttggt ctttgtccttgtgccaagtatgaaattagacaaacagaacacctggctttactagtaatc catgatgtagacccagaggatgctgggagttacacatgtgacactggtgaccggcaaagc actgcgcatctagctgtgaagggtatgcttgctaagacctgttgtttgtggtggagatac ttgagttgcaaattaatcaactacttgctttttaaactatcaataaagaacacatttggg atttgacatgatttaagtgttaagacgtgaggctctcttccacctccgcttcatacttta gtagtttaatgtgtgtggcagctttctctcagatgtcctaagtgttctctcctcatttcc ttcacctcgtccactgcagcccagcctgttcatttcaaaaccaagctgcagaacattgaa agacaggaaggggagagcgctagtcttcgctgtgagaccacaaagccgggagccagtgtt gtctggaggtgtggtgacagggtgctggcatccagcagcaagtatcacctaaaacaggaa ggaaccatagttgagcttgtcatctataaactggaaggagccgactcaggagaatactcc tgtgatgcgggcaataagaggacttcagctgtcctcactgtgcaggaggtcgaggttaaa atactgaagttcttggagagctgccttgtatacgagggtgaagatgtccgctttgaatgt cgggtttctcgtgaggaggcacctctggcccagtggaaactccaggatgtcccactacag aataatgaaatgaacctgatcaagtctgagggccgggtacacagcctcacactccggggc gtcaccgcagctgactcaggaacagtcactttcacagtgggtaaccacacttccactgct tctctgacagtcagagcggcacctgtactattcaagaaggagctggaaagtcaggaggcc actgaaggagacaaggccaccctgtcctgcgagacatccagcgccgattgcaaggtggtc tggctgaaggactcaactgtgctcacccatggggagaagtacagtatggagcagacagct accacccacagcttggtcatactccagctgaatatgaaggatagtggagaatatacctgc gacacaggggacaagaaaagtacagctaccctgactgtgaaagaacatgtgcgcctcacc cgagaactctgcgacatgactgtgcccactgggcaggatgctgtctttgaggttgagttg tcacactcaggtgtgacaaacggggaatggtggcttggagacaacctcctccaaaataac gatctgaatcaaatgagcagccaaggcagagtgcatcgtttgacccttaagatggtgacc acagatgagtcgggggatgttgcctttgtgttgggagaagagaagactgtggcctgtctt ctggtggaggagaaacccaaagtgttaatactagagaagccacacaacactgtagcagta gagggtgaaactgtctctctggcctgcaccatctctgatgccaaggccaccttcacctgg atgagaaacaaggtggccatccaagcaggtctcaagtatgacctgaggaacaacggagcg ttccaccagcttcgtatccacaacgtggtgcctgaggactcaggaacgtacacttgtgac actggagatgcacagtgtgacgtcaccttgactgtggaaggtgccccagtgttcttccac aaagagctcaagaatcacgatgccatagagggtgatgatgttaccctgcgctgtgagctg tctaagccaggtgttcgtgttgagtggaggaaaggaggcatggtcctcctgcccggtaag aagtgtgagatgaggcaagaagggtgcattcaagagctctgtatatggaacctggagcct gaggacagtggctactacacctgtgatgcaggagaccagctcaccacggcttctttggca gtgcaagtgaaagaagtcttcattgtgtctggtcttaagaccactgacgtctttgttggg gaatgggcaaccttctcctgccagctgtctggtagggcacctgaaaaggtgcagtggtgg ctggatggcaccttgttggagaatagcccctttagtgagatagggctgagccagggcaac atccacacactctccttaaagaacctggccaccgatgactctggcactgtcactttcgaa gctggcagtgtaacatcaacagccaagctcttagtcaaagatcccacagttgaagtggtg aacgagatggaggaccttcgggtgcttgaaaaccaaccggctgagttcatctgccagttc tcacggccggtcaaggctcagtggaagaaagacgggcagcctttgcagcctgatggccga agggtggtagtggagcaggactggaatgtggctcgcttgtacattagccgcgtgtccgct gaggacaggggcacttactcctgtgaggcagagttggcctgtgcggttgcttcactttat gtggaaggcaaacccattgacattgtccagggcctggagaatgtagaaacctttgatgga ggtgaagtgctgcttgagtgtgccctctctcgtcccgagagcaaagattgctgctggctc tttgatgggaaaccagtgaaggaatcccgtaatgctgagattgtgacatttgagagtggt cgtcgtcatttactcctgctgaaagagttgcgagtgaaagacagttgcacagtgaccttc aaagctggcaaagcctccacatctgcccaactctctgtcaaacgctggcagctggacgtt gtgaaggctctggaagacacggtggctgcagtgggagagaaggttgagttttgtgttgag ctcaccgagcctgtccctacagcagaagtagcctggtatgctaatggtatcgagctcaag cccaatgacctctgggctacgagggctgacggctgttcttatcgcctcgtcctgagaaag gcccctcttttgccacagcaggaaattacatttgctgctagagatgctctctctttggcc aagctcaccatcatcactgtacctgatccaccagaggacgcagaggtcctcagtaagacc gaaaagtctgtcaccctctcgtggttcactcctctacatgatggagggagtcccattctg ggctacaggttggagatgcggctggtagacagttccctctggcttccctgtcaatctgaa cctgtgtgtaacacagagtttgtggttgaaaatcttattccgggaagtagctacaggttt agagtggcagccaccaacagagctgggattggagagcctgttgagttgcctcagactgtg cggcttgatacacccatgcagccaccaattagcccaggtatagaggcaaaacaggtagag gctgagatgatggggcaacccagtctgcctccagaagctgctgaagaaggtgatgtccat gagctttgggaggaatcggccaagaaacgtcgcatgagtcgagaacctacactggactcc atcactgaacaaccggaggatgacggtaaaggtggtcaaaagaaatcaggacagatagag ctgaaggcctcagagaaagtggaaataaaatcaggagaaaaggagcaggtcattgtgtct aagaagcagacagagtccaaattgtacaccagctctgagaatgagtctgtttctgggggt tcaacgcttgtctcctacctcaagaaaagcagcacgtctactgtcacagcgaccaatgag gcacagactatgactactgaaaggttctttgcacatttccagaaggcagaccagaaaaca gtgcagcagactaaagtggaaacaagcacaattcagcagacagacgcaaaacaggtgtct acagaggagactaacatcatggagatcagtaaagaggatgagcctgagcttagagatgct gccattaagattcaagctgcgttcaagggctacaaagcccgcagggacatgcgccctgtc tttaaagaggccttcaaagaccagaccaaagaacctaatggcaccatacatctagaatgt gtggcagaaggtaaacctgataaggtgcggtggctgaaggatggagaatccctgactgat ggcaagcaccaccatatcgatatctacaatgatggcacttgctcactggtcatcactgcc atcaccacaaaagatactggggtctacacgtgtgaggtcaccaacaagtttggagttact tctcacagtggtaaagtcacagtaggaacagtgagagaatcatctgggcggcggccgctg accgtgggctacagtgccgacagcgagcctgacagctcctcaggaagtgagatggatgag tcactgaggcaggctagcaaacgtcttcggcgcctgcttcgcacaagtctcccaccaaat gttgaggaagaattatttgtcagcgcagatgaaggggacctgggtcctccagatccccac tcttaccgggaggacgactgttacatctacattcgctttgagtcccggacagaagctgag gttgcctcgaagaggttccaggagatgtttacaatccatggggttcctgtggaaaccacc atcctggactcagggcctcttaaagtggagctgcgaattagaaagatgggctacacgcaa gatggcacacagacccccacaccagatagacagcctcctgcatttatggctggagcccag gctgccccagtcttcttgacagagctacaaagtcaggatgttccagacggttatccagtc agctttgactgtgttgtgattggcaagccccctcccaccgttcgctggtacaaggacggc aaattgctggaggagaatgaccattacatgatcaatgaagaccaggagggctgccaccaa ctcatcattaccactgtgctgcccacggacatgggcgtctatcgttgcacagctgaaaac agcagcggcatcactgccactaaggctgaactcagggttgacatgtcttgcagctcagat tatgacactgctgctgatgccactgagacatcttcctatgtcagtgccaagggatacctt tcaagggaaactgagacatttgagtctgtcgctgaagatgatcagctaccacaagttgtg gatgaacttcatgatgttcatgtctgtccaggttcacctattgctaagctgcagctcaaa ttaaagggcttccccaaacccagaatatactggttcaaagatggccaccctctgcgacct tcagaaaggattctgttgataacagagagagatgttcatggcgtggagatcctggaggtg aagaaagaggatatgggggagtactctgcttacatcagcaatgcagctggttctgcttac tcctctgcccgcctgatagttctgcgtccaggggagattatgccacaagataaaagagac cccaaggagcccctggtgccaccccgcttcattgaaaggttcagcaacaggaaggtgaaa caaggatccagcatcactctgtctgtcaaagtagaaggctctcccactccaatggtctcc tggctaaaggaggaatcaatggaagatgtcctgtggatcaagcctgataccaagggatac aaaatagcaagctcggggcgccagcacagcctcatcttgatggacgtgggcacagaatac actggcgcctacacctgcatcgccacaaataaagcaggacagtccatctgcactgcccac ctcgaggttgatgatgtaccacaacaaaagaaagagactaatgcctcagaggtgtttgga tttacaattagtcctccagacgaggaggcgggcagaggaaaagagagtaaattaccctac ctaggtgaagtaggtacagaggaattcctcatgaaactgacctcccagatcactgaaatg gtatcggcaaagtttacccaagacagtttacagaatcatgaagtgctccagtggatgaaa tcttggcccaaaactaccacttcattacgcgttccaggtgttgacagtgatgatgagacc aagaccccttctccatcacctcatcacggtcgctctcgtcctccctccctcattgctgac tcctcctctgagtcagatgagggggatgccaggggagagatgtttgacatctatgtggca acggctgactacacccccaccatatcgatcaaagaatccatctctctaaaggagggacag tatgttgaggttttggactccgctcatccacttaaatggttagtccggaccaaacccacc aaaactacaccatcccggcaaggctgggtctcacctgcctacctggacaagaaactcaaa ctctctgctgatacgagtgaccttccagagacgaatgaagaggaggtgtctgagggggaa tacaagaggaaattattccaactggtccaagacctgataaatggtgaatcagagtttgta aaagaggtcgacttctttacctcccatcacgtgaagcatgcagacagccctgatgcaccg cctgatgtcagcagccagaaggaagccatattcaggaacattgatgatatcaagtctttc catagcaaggcattcctcccaaagctgaacgactgtgaaacagatgatgacgtagccatg tgcttcctgaagaacaaggagggctttgagaagtacctcgagtatcttgtcggtcagagt aaggctgaatctgctgtcaatgacaaggccgttcaccgcttcttcaaggagtacacagag aaagtgcaagccggtgccgaccctgcagatccccctgtacacagcatcaacgccagcctc caacacccactggagaggattcagaagtacaaggccgtcctcaaggagctcatccgaaac aaggcaaagaacggccagaactgctgcctgctggaagaagcgtatgcgatggtgtctgcg ctccctcagcgctctgagaatacccatcatgtctccatgatcgagaactatcctgctaca ctggaagtattaggagagccaatgagacagggacccttccaagtgtgggaaggtgctcca ggaattaggacgtcctctaggggtcaccaccgccacgtcttcctgtttaagaactactgc atcatctgcaaacccaagagagacagcaacactgatacacaagcatatgtctttaagaac atgatgaagttgaataacattgatgtgaatgagacagtggagggtgatgaccgtgccttt gagatctggcatgaacgtgaggactctgtgaggaaatacaccttgcaggcccgaactatt accatcaagaactcatggctgagagacttcagagaactgcagcagcgatacagcatgcct acatggagtcctcctgactttgatgaaattctggcaaactgcacagcagagctgggtcag actgttaaactggcctgcaaagtcactggattacccaaacctgcggtcacttggtacaag gacggacgtactgtggaggcagaccctcatcacatcgtcatcgaggaccccgatggttcc tgcacgctgatcttggataacatgacagcagatgattctggccagtacatgtgctttgcc acaagctcagcgggcaatgccagtactcttggcaagatcacagttcaggtgcctcctcgt tttgtgaataaaatgaggaatgctatatttgttgctgctgaggacgctcagttcacctgc gtcatacagagtgcccccaaccccaagatcaggtggtttaaggatggcaggctgctcacc gaccaggaaaaatatcagaccttcagcgagctccgcagtggggttcttgtcttggtaata aaaaacctgacagagagagacctgggacactatgagtgcgagttgtccaaccgcctgggc aatgccaagtgtgctgctgacttagttcctccctctgctgtgactcgcactggtgagcag gccatcactattgaagttactgagcaggagactagaataccaaggaaaaccatcatcatt gaggagactataaccaccgtggtgaagaacccacgtatgaggaggcacaagtcccccggt ttgactgttgctggagcctaccgctcggagacctccaccccggagccccccacagccagg ctgaggaggatgcccactccaagaaagaccactatcccaaccctctatgtttctcaaccc gagggtgctgaagcaagagccatggagagcaggcccacgtgggtggaggttgaggaggtc atcgagtataaggtcaataaatctcccaggctgccccggaggagaggcatctctccggca ttgtctgaccgcgcagccgctccctccagatccaaaaggtctcctccggaaaacccaaac actaacaattgcaacaacaagctggtggagcaggctcagctgcagggagacgtcagcagc tcgccgctctcctgggaagaagaggagggtaacgtttcctctgattctgtcactggagag ccacatgaactctcttctgtcctcactccagctgcagaggacagtgacgacctggatgat gaacaaactgtcatctttgaacccgatgatgaagatgatgactcactcggggatcaggag cctaagattctgacacaaggaggccgtgttctgaccctagaagacttggaggattacgtg ccagaagaaggcgagacctacggctcctccagcgcccccgctgcggaaaagccctgtgag atctctgtgctccagagggagatcggcgggtccacagtgggacagccggtgctcctcaac gtggggcggcccgtcgtggtcccgaggcagaggagcggcttcttcggccgcttcagggag catctctccagcagccttttcacatctgctgccccccaagccagcggagcccggtccagg acggaaaggcacgtccccatccaagtgagccacgcaaagatggaagtgaagccttcatac tgctcagaggtgcagagagtcgagtgcgggcagcagagctttaaaaccaaagtgtcaact cagacctatggctacacatcagtgggcaaccctgtcactcttcaaattagtgataacctt tatcagaaccagtag

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