Capra hircus (goat): 102171504 Help Entry 102171504         CDS       T02910                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism chx  Capra hircus (goat) Pathway chx04062   Chemokine signaling pathway chx04151   PI3K-Akt signaling pathway chx04217   Necroptosis chx04550   Signaling pathways regulating pluripotency of stem cells chx04630   JAK-STAT signaling pathway chx04658   Th1 and Th2 cell differentiation chx04659   Th17 cell differentiation chx05161   Hepatitis B chx05162   Measles chx05166   Human T-cell leukemia virus 1 infection chx05169   Epstein-Barr virus infection chx05200   Pathways in cancer chx05203   Viral carcinogenesis chx05223   Non-small cell lung cancer chx05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102171504 (JAK3)    04151 PI3K-Akt signaling pathway     102171504 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102171504 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102171504 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102171504 (JAK3)    04659 Th17 cell differentiation     102171504 (JAK3)    04062 Chemokine signaling pathway     102171504 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102171504 (JAK3)    05203 Viral carcinogenesis     102171504 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     102171504 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102171504 (JAK3)    05161 Hepatitis B     102171504 (JAK3)    05162 Measles     102171504 (JAK3)    05169 Epstein-Barr virus infection     102171504 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     102171504 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:chx01001]     102171504 (JAK3) Enzymes [BR:chx01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102171504 (JAK3) Protein kinases [BR:chx01001]  Non-receptor tyrosine kinases   JAK family [OT]    102171504 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl Kdo ABC1 SH2 Haspin_kinase Motif Other DBs NCBI-GeneID:  102171504 NCBI-ProteinID:  XP_017906892 EnsemblRapid:  ENSCHIG00000009142 UniProt:  A0A452DZ12 LinkDB All DBs Position 7:complement(103471829..103490767) Genome browser AA seq 1104 aa AA seqDB search MAPPSEETPLISQRSCSLSSSEAGALHVLLPPRGPGPPQCLSFSFGDHSAEDLCVYAAKA SGILPVYHSLFALALEDLSCWFPPSHIFSVEDTGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRHDLVSGRLRVGLSLKEQGECLSLAVLDLARMALEEAQR PEELLKTVSYKVCLPPGLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMVKYIM DLERLDPDRAAETFRVGLPGAAGGQDTPGLLRVAGGSGIAWSPGEHEVLQPFCDFPEIVD ISIKQAPCIGPAAEHRLVTITRTDNQILEAEFPGLPAALSFLALVDGYFRLTTDSRHYFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKTEGSRPGSYVLRRSPQDFDSYLLTVCVLTP LGPDYKGCLIRCDPTGTFSLAGLGRSHSSLRELLAACWNGGLHVDGVELYLTFCCNPRPK EKSNLIVVRRGCNPPTSSPVQPQFQCQLSQMTFHKIPADSLQWHENLGHGSFTKIYRGCH HEIVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVRLGALDTYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGT DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GITVPISTLEPAKKLQFYQERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL ITSDYELLSDPTPGTLAPRDGLWNGTQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPEQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDAGRLLLYASQICKGMEYLGSCRCLHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPSEVHELMKLCWAP NPQDRPSFSALGPQLDALWSGSRG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaggagacacccctgatttctcagcggtcctgcagcctctcctct tcagaggctggtgcgctgcacgtgctgctgccccctcggggccctggacccccacagtgc ctgtccttctcctttggggaccactcagctgaagacctgtgtgtttacgctgctaaggcc agtggcatcctgcccgtgtaccactccctctttgctctggctttggaagacctgtcttgc tggttccccccgagccacatcttctccgtggaggacacgggtacccaggtcctcgtctac aggctccgcttttacttccccaactggtttggactagagaagtgccaccgatttgggcta cgaaaggacttggccagtgccatcttagatctgccagtcctggagcacctctttgctcag caccgccatgacctggtgagcggccgccttagggtaggcctcagcctcaaggaacagggt gagtgtctcagcttggctgttctggacctggcccggatggccctcgaggaggctcagcgg cccgaggagttgctgaagacggtcagctacaaggtctgcctgccccctggcctacgcgac ctgatccagggtttgagcttcgtgactcggaggcgcatccgaaggacagtgcgccgggcc ttgcgccgcgtggcggcctgccaggctgacaggcactcgctcatggtcaagtacatcatg gacctcgagcggctggatccagacagggccgctgagaccttccgcgtgggtctccccggc gctgctggtggtcaggatacgccggggctgctccgtgtggctggtggcagtggcatcgcc tggagcccaggagaacacgaggtcctccagcccttctgcgactttccagaaatcgtggat atcagcatcaagcaggcgccgtgcattggcccggctgcggagcatcgcctggtcaccatc accaggacagacaatcagatcctggaggccgagttcccggggcttcccgcagcgttgtcc ttcctggcgctcgtggatggctacttccggctgaccacggactcgcggcactacttctgc aaggaggtggcgccgccgcggctgctggaggaggtggctgagcagtgccatggccccatc accctggattttgccatcaacaaactcaagactgagggctcacgtcccggctcctatgtc ctccgccgcagtccccaggatttcgacagctacctcctaactgtttgtgtcctgaccccg ctgggcccggattataagggctgcctcatccggtgcgaccccacaggaaccttttccctg gctggccttggccgttcccacagcagtcttcgagagctcctggcagcctgttggaatggt gggttgcatgtggatggggttgagctatacctcaccttctgctgcaaccccagacctaaa gaaaagtccaatctgattgtggtccggagaggctgcaacccacccacatcatcccctgtt cagccccaattccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctgcagtggcatgagaacctaggtcacgggtccttcaccaagatttatcggggctgtcac catgagattgtggatggggaggcccgagagacagaggtgctgctcaaagtgatggacgcc aagcacaagaattgcatggagtcattcctggaagcagcaagcttgatgagccaagtgtca taccagcatctcgtattgctccacggcgtgtgcatggctggagacagtatcatggttcag gaatttgtacgcctgggagcgctggacacatatctacgcaagtgtggccacctagtgcca gccagctggaagctacaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggtctccctcatggcaatgtctcagcccggaaggtgctcttggctcgtgaagggact gatgggaacctgcctttcatcaagctgagtgacccgggtgtcagccccactgtgctaagc ctagagatgctcactgacaggatcccctgggtggcccctgaatgtctccaggaggcccga acacttggcttggaagctgacaagtggggctttggagccacagtctgggaggtgttcagt ggtatcacagtgcccatcagcaccctggagcctgccaagaagctccagttttaccaggaa cggcagcagttgcctgcccccaagtggatggagctggccctgctgatccaacagtgcatg gcctatgagccaggccagaggccctctttccgcgctgtcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggcaccctggcgccccgtgat gggctctggaatggcacccagctctacgcctgccaggaccctaccatctttgaagagaga cacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc tatgacccgctgggcgacaacacaggggccctggtggccgtgaagcagttgcagcatagt gggccagaacagcagcgggacttccagcgggagatccagatcctcaaagccctccacagc gacttcattgtcaagtaccggggtgtcagctatggcccaggccgccagagcctgcggttg gtcatggagtatctgcccagtggctgcctgcgcgacttcctgcagcggcaccgcgcccgc ctcgacgctggccgcctgctcctctacgcctcacagatctgcaagggcatggagtacctg ggctcctgccgctgcctgcaccgcgacctggcagcccggaacatcctggtggaaagcgag acgcacgtcaagatcgccgacttcggcctcgccaagctgctgcctctcgacaaagactac tacgtggtccgcgagccaggccagagccccatcttctggtatgccccagagtccctctcg gacaacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtacgagctc ttcacctacagtgacaagaactgtagcccctcagccgagttcctgcggatgatgggatgt gaaagagatgttccagccctctgccgcctcctggagctgttggccgagggccagaggctg cccgcacctcctgcctgtcctagtgaggttcatgagctcatgaagctgtgctgggcccct aaccctcaagaccggccatcgttcagtgccctgggcccccagctggatgcactgtggagt ggaagccggggatag

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