Capra hircus (goat): 102187468
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Entry
102187468 CDS
T02910
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
chx
Capra hircus (goat)
Pathway
chx00010
Glycolysis / Gluconeogenesis
chx00020
Citrate cycle (TCA cycle)
chx00620
Pyruvate metabolism
chx00785
Lipoic acid metabolism
chx01100
Metabolic pathways
chx01200
Carbon metabolism
chx01210
2-Oxocarboxylic acid metabolism
chx04066
HIF-1 signaling pathway
chx04922
Glucagon signaling pathway
chx05230
Central carbon metabolism in cancer
chx05415
Diabetic cardiomyopathy
Module
chx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
102187468 (PDHA2)
00020 Citrate cycle (TCA cycle)
102187468 (PDHA2)
00620 Pyruvate metabolism
102187468 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
102187468 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
102187468 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
102187468 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
102187468 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102187468 (PDHA2)
Enzymes [BR:
chx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
102187468 (PDHA2)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
102187468
NCBI-ProteinID:
XP_005681461
EnsemblRapid:
ENSCHIG00000008223
UniProt:
A0A452DWD8
LinkDB
All DBs
Position
6:complement(29171873..29173203)
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AA seq
391 aa
AA seq
DB search
MKKMLTAAVSRVLSGVTQKPASRVLVASCKYSNNATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYKMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLTVRSILSELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNNEVCLTLYGDGAANQGQISEAYNMAALWNLPCIFICENNRYGMGTSVERAAAS
TDYYKRGNFIPGLRVDGMDILCVREATKFAADYCRSGKGPMLMELLTYRYHGHSMSDPGI
SYRTREEIQSVRSKSDPIMLLKDKMVNNKLASVEELKEIDAEVRKEVDDAAQFAMTDPEP
PLEELGHHIYSSNPPFDIRGANQWIKFQSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatgctgactgctgctgtctctcgcgtgctgtctggtgtcacccagaagccc
gctagcagagtgcttgttgcctcctgtaaatattcaaacaatgctaccttcgagattaag
aaatgtgatctttatcggttggaagagggcccccctgtcaccaccgtgctcacccgggag
gatggactcaaatactacaagatgatgcagactattcgtcgaatggaactgaaggcagat
cagttgtataaacagaaatttattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgtgtgggtcttgaggctgggataaatcccaccgatcacgtcattacatcctatcgg
gctcacggcttatgttatacgcggggacttactgtccgatcaattctttcagagctgaca
ggacgaagaggtggttgtgctaaaggaaaaggagggtccatgcatatgtatgccaagaac
ttctatgggggcaatggcattgtcggcgctcagggaccactgggagctggtattgctctt
gcctgtaaatacaaggggaacaacgaggtgtgtttgactctgtatggtgatggcgctgct
aatcagggtcagatatctgaagcttacaatatggcggctttgtggaatttaccttgcatt
ttcatctgtgagaataaccgctatggaatgggaacatctgtggagagagctgcagccagc
actgattactacaagagaggcaattttatccctggactaagagtagatggaatggatatt
ctatgtgttcgggaggcaactaagtttgcagctgactattgtagatctggaaaggggccc
atgctgatggagctgctgacataccgttatcacggacacagtatgagtgatcctggaatc
agttaccgtacacgagaagaaattcagagtgtaagaagtaagagtgatcctattatgctt
ctcaaagataaaatggtaaacaacaagcttgccagtgttgaagaattgaaggaaattgat
gctgaagtgaggaaagaagttgatgatgcagctcagtttgctatgactgatccagaacca
cctttggaagaattaggccatcacatctacagcagtaatccacctttcgatattcgtggt
gcaaatcagtggatcaagtttcagtcaatcagttaa
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