Carboxydothermus hydrogenoformans: CHY_0335
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Entry
CHY_0335 CDS
T00287
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
chy
Carboxydothermus hydrogenoformans
Pathway
chy00790
Folate biosynthesis
chy01100
Metabolic pathways
chy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
chy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CHY_0335 (folC)
Enzymes [BR:
chy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CHY_0335 (folC)
6.3.2.17 tetrahydrofolate synthase
CHY_0335 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF6066
Motif
Other DBs
NCBI-ProteinID:
ABB15316
UniProt:
Q3AF86
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Position
290771..292069
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AA seq
432 aa
AA seq
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MNYNEALEFLSNLTKFGINLGLGRISELLKRLGNPQEKVKVVHIGGTNGKGSVCSLTASV
LAEAGYKTGLFTSPHLSRYTERYKINGKEISPERVSQLVTEIRPLLLAMVEEGFEHPTEF
EVSTAMAFKYFAEEEVDFVVLEVGLGGLIDSTNVVSRPEVVAITNVGMDHMDYLGNTITE
IARVKAGIIKPGVPVVTAATGEALEVIKEVAKEKNSPLLDVNKDIVLNLKEKSLKGQVFD
LIYRGETYPEIKIRLLGAHQLLNAKTSFGILNILREKYNIPVEAIYRGFSNATWSGRFEY
IPGNPPVLLDGAHNHDGVRALRQAFTDYFPGVKPVLLLGVLADKEREKVVAELLDLPLEV
VVTRPPTPRAGDITVLARLFKEKGVRVKVIEEPTEALSYGLEIAQEYQTLLLITGSLYMI
GEIRPLLLQDRD
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgaactataacgaagcgctggaatttttaagtaaccttaccaaatttggaattaatttg
ggtttagggaggatttctgaacttttaaaaaggcttggcaatccgcaggaaaaggtaaag
gtagttcacatcggtggaacaaacggtaaggggtcggtttgttcgttaacggcttcggtg
ttggcggaggcggggtataaaacggggctttttacctcgccccacctttcccggtatacc
gaacgctataaaataaacggtaaagaaatttcgccggaaagggtttctcagctggtgacg
gaaataagaccgttacttttggcgatggtagaggaaggttttgaacatcctaccgagttt
gaagtgtccacggcgatggcttttaagtattttgccgaagaggaagttgattttgtggtt
ttagaagtaggactgggaggcttaattgattctaccaatgtggtttcccgtccggaagtt
gtggcgattaccaatgtgggaatggaccatatggattatctgggaaataccattaccgaa
attgcccgggttaaggcggggataataaagccgggagtgccggtggtaaccgcggcaaca
ggggaggctctggaagttatcaaagaggtagcaaaagagaaaaacagtccccttttggat
gttaataaggacatcgttttaaatttaaaagaaaaaagcttaaaagggcaggtttttgac
cttatttaccggggtgaaacctatccagagataaaaatccgccttttaggagcccatcag
cttttaaatgccaaaacttcttttggtattcttaatatcctgcgggaaaaatataacata
ccggtggaagcaatttaccggggatttagcaacgccacctggtcggggcgttttgagtat
attccgggaaatccgccggtacttctcgatggggcgcacaatcacgatggagttagagct
ttaaggcaagcttttactgactattttcccggtgtaaagccggtactgctcctgggagtt
ttagccgataaagagcgggaaaaagtggtggcggagcttttagatttacccttagaagtg
gtagtgacccgaccgccaactccccgagcaggagatatcaccgtcttagcaaggcttttt
aaagaaaaaggggttagggtgaaggttatcgaagaaccgaccgaagctttatcttacggc
ctggaaattgcgcaagaataccaaaccctcttattaattaccggttccctttatatgatt
ggcgaaatccgccctttacttttgcaggatagagattag
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