KEGG   Cebus imitator (Panamanian white-faced capuchin): 108309821
Entry
108309821         CDS       T08783                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00562  Inositol phosphate metabolism
cimi01100  Metabolic pathways
cimi01521  EGFR tyrosine kinase inhibitor resistance
cimi04068  FoxO signaling pathway
cimi04070  Phosphatidylinositol signaling system
cimi04071  Sphingolipid signaling pathway
cimi04115  p53 signaling pathway
cimi04140  Autophagy - animal
cimi04150  mTOR signaling pathway
cimi04151  PI3K-Akt signaling pathway
cimi04218  Cellular senescence
cimi04510  Focal adhesion
cimi04931  Insulin resistance
cimi05165  Human papillomavirus infection
cimi05166  Human T-cell leukemia virus 1 infection
cimi05200  Pathways in cancer
cimi05206  MicroRNAs in cancer
cimi05208  Chemical carcinogenesis - reactive oxygen species
cimi05213  Endometrial cancer
cimi05214  Glioma
cimi05215  Prostate cancer
cimi05218  Melanoma
cimi05222  Small cell lung cancer
cimi05224  Breast cancer
cimi05225  Hepatocellular carcinoma
cimi05230  Central carbon metabolism in cancer
cimi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cimi05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    108309821 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    108309821 (PTEN)
   04070 Phosphatidylinositol signaling system
    108309821 (PTEN)
   04071 Sphingolipid signaling pathway
    108309821 (PTEN)
   04151 PI3K-Akt signaling pathway
    108309821 (PTEN)
   04150 mTOR signaling pathway
    108309821 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    108309821 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    108309821 (PTEN)
   04218 Cellular senescence
    108309821 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108309821 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108309821 (PTEN)
   05206 MicroRNAs in cancer
    108309821 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    108309821 (PTEN)
   05230 Central carbon metabolism in cancer
    108309821 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108309821 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    108309821 (PTEN)
   05214 Glioma
    108309821 (PTEN)
   05218 Melanoma
    108309821 (PTEN)
   05215 Prostate cancer
    108309821 (PTEN)
   05213 Endometrial cancer
    108309821 (PTEN)
   05224 Breast cancer
    108309821 (PTEN)
   05222 Small cell lung cancer
    108309821 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108309821 (PTEN)
   05165 Human papillomavirus infection
    108309821 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    108309821 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    108309821 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108309821 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cimi01009]
    108309821 (PTEN)
Enzymes [BR:cimi01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     108309821 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     108309821 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     108309821 (PTEN)
Protein phosphatases and associated proteins [BR:cimi01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    108309821 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 108309821
NCBI-ProteinID: XP_017391864
Ensembl: ENSCCAG00000021453
LinkDB
Position
Unknown
AA seq 403 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaggaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccgccacagctagaactt
atcaaacccttttgcgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagtttatgtac
tttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctgtgtgatcaagaaatt
gatagcatttgcagtatagaacgtgcagataatgacaaggaatatctagtacttacctta
acaaaaaatgatctggacaaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga

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