KEGG T03264: 100401212

Callithrix jacchus (white-tufted-ear marmoset): 100401212

Entry

100401212         CDS       T03264

Symbol

HSD11B1

Name

(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1

K15680

corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]

Organism

cjc Callithrix jacchus (white-tufted-ear marmoset)

Pathway

cjc00140

Steroid hormone biosynthesis

cjc00980

Metabolism of xenobiotics by cytochrome P450

cjc01100

Metabolic pathways

cjc05204

Chemical carcinogenesis - DNA adducts

Module

cjc_M00109

C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone

Brite

KEGG Orthology (KO) [BR:cjc00001]
09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100401212 (HSD11B1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100401212 (HSD11B1)
09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100401212 (HSD11B1)
Enzymes [BR:cjc01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     100401212 (HSD11B1)

SSDB

Motif

Pfam:

adh_short adh_short_C2 KR THF_DHG_CYH_C DUF1776 Epimerase 2-Hacid_dh_C Shikimate_DH Pyr_redox_3 Pyr_redox_2 AdoHcyase_NAD

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

19:33469897..33524706

AA seq 291 aa
MAFMKKHLLPILGLFMAYYYYSAYEEFRPEMLQGKKVIVTGASKGIGREIAHHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMAFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNFFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVIVSSVAGKVAYPMI
SAYSASKFALDGFFSSIRKEYLMAKVNVSITLCVLGLIDTDTAMKAVSGIINMQAAPKEE
CALEIIKGGVLRQEEVYYDSSLWTTLLLRNPSRKILEFLRSTSYSTDRLIN

NT seq 876 nt +upstreamnt +downstreamnt
atggcttttatgaaaaaacatctcctccccattctggggctcttcatggcctactactac
tattctgcatatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaagggattggaagagaaatagctcatcatctggcgaagatgggagcccat
gtggtggtgacagcgaggtcaaaagaaactctacagaaggtggtatcccactgcctggag
cttggagcagcctcagcgcactacattgctggcaccatggaagacatggccttcgcagag
caatttgttgcccaagcaggaaagctcatgggaggactagacatgctcattctcaaccac
atcaccaacacttctttgaatttttttcatgatgacattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttatgtggtcctgactgtggctgccttgcccatgctgaagcag
agcaatggaagcattgtcatcgtctcctctgtggctggaaaagtggcttatccaatgatt
tctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tatttaatggccaaggtcaatgtgtcaatcactctctgtgttcttggcctcatagacaca
gacacagccatgaaggcagtttctgggataatcaatatgcaagcagctccaaaggaggaa
tgtgccctggagatcatcaaagggggagttctgcgccaagaggaagtgtattatgacagc
tcactctggaccactctcctgctgagaaatccatccaggaagatcctggaatttctccgt
tcaacgagttatagtacggacagattgataaactag

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