KEGG T04062: AFK66

Cronobacter malonaticus LMG 23826: AFK66_005910

Entry

AFK66_005910      CDS       T04062

Name

(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase

K11754

dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

Organism

cmj Cronobacter malonaticus LMG 23826

Pathway

cmj00790

Folate biosynthesis

cmj01100

Metabolic pathways

cmj01240

Biosynthesis of cofactors

Module

cmj_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Brite

KEGG Orthology (KO) [BR:cmj00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    AFK66_005910
Enzymes [BR:cmj01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     AFK66_005910
    6.3.2.17  tetrahydrofolate synthase
     AFK66_005910

SSDB

Motif

Pfam:

Mur_ligase_M Mur_ligase_C MeaB

Other DBs

NCBI-ProteinID:

ALX77843

LinkDB

Position

1160949..1162217

AA seq 422 aa
MEKQHLPQATSPLATWLSYLENLHGKTIDMGLERVSRVAALLDVVKPAPFVFTVAGTNGK
GTTCRTLEAVLMAAGYRVGVYSSPHLVRYTERVRVQGEELAESQHTAAFAEIEAVRGETS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNLVDCDVAVITSIALDHTDWLGPD
RESIGREKAGIFRAGKPAVVGEPDMPHTIAQVAQEKGARLLCVNDAWRYEAERDGWRFSD
GDGELTHLPLPQVPQPNAATALAALRVSGLAISEQAYRDGIARATLPGRFQIVSEAPRII
LDVAHNPHAAGYLAQRLAQSPSAGRVLAVIGMLHDKDIAGTLACLERVVDSWYCAPLDGP
RGARAEELAEHLQASAVFDSVAQAWHAALADAQPADTVLVCGSFHTVAAVMEEMDAGRRG
GE

NT seq 1269 nt +upstreamnt +downstreamnt
atggaaaagcaacaccttccccaagccacgtcgcctctggccacgtggctttcttatctg
gaaaacctgcacggtaagaccatcgacatgggccttgagcgcgtctcgcgcgtggcggca
ttgcttgatgtagtaaaacccgcgccgtttgtcttcaccgtcgcgggcactaacggcaaa
ggcaccacctgccgcacgctcgaagcggtgctgatggcggcaggctatcgcgtgggcgtc
tacagttcgccgcacctggtgcgctacaccgagcgcgtgcgcgtgcagggcgaagagctt
gcggaaagccaacacaccgccgcgtttgcggagattgaagccgtgcgtggtgaaacgtcc
ctcacgtactttgaatacggcacgctgtccgcattgtggctctttaagcaggcgcagctg
gatgtcgttattctcgaagtcgggctcggcgggcgactggacgccaccaacctggtggat
tgcgatgtggcggtcatcaccagtatcgcgctcgatcacaccgactggctggggccggat
cgtgaaagcatcgggcgcgagaaagccggtattttccgtgcgggcaaaccggcggtggtg
ggcgagcccgatatgccgcacaccatcgcgcaggtggcgcaggagaagggcgcgcggctg
ctttgtgtgaacgacgcctggcgctatgaggcggaacgcgacggctggcgctttagtgac
ggcgatggcgaactgactcatcttccgctgccgcaggtgccgcagcctaacgcggcgacg
gcgctcgccgcgcttcgcgtaagcggccttgcgatcagcgagcaggcttaccgcgacggc
atcgcgcgcgccacgctgccggggcgtttccagattgtgagcgaggccccgcgcatcatt
ctggatgtggcccataatccgcacgcggcgggctatctggcgcagcggctcgcgcagtcg
ccatccgccgggcgcgtgctggcggttatcggtatgctgcatgataaagatatcgccgga
acgctcgcctgtctggagagggtcgtggatagctggtattgtgcccctctggacgggccg
cgcggcgcccgcgccgaagagcttgcggaacatctgcaggccagcgctgtctttgatagc
gtggcgcaggcctggcacgcggcgctggccgatgcgcagcctgctgatacggtgctggta
tgcgggtcgtttcataccgtcgcagcggtaatggaagagatggacgcggggagacgaggt
ggcgagtaa

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