Cupriavidus necator N-1: CNE_1c24920
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Entry
CNE_1c24920 CDS
T01564
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cnc
Cupriavidus necator N-1
Pathway
cnc00790
Folate biosynthesis
cnc01100
Metabolic pathways
cnc01240
Biosynthesis of cofactors
Module
cnc_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
cnc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CNE_1c24920 (folC)
Enzymes [BR:
cnc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CNE_1c24920 (folC)
6.3.2.17 tetrahydrofolate synthase
CNE_1c24920 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AEI77810
UniProt:
G0ERC8
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Position
1:complement(2576093..2577403)
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AA seq
436 aa
AA seq
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MPVFHTLPEWLAHLETAHPVGIDMGLARITRVKEALGLRIDAVVFTVGGTNGKGSTCAML
ERILLEAGYKVGCHTSPHLISFNERARINGEIATDAQLLPHFEAVERARNSFADPVSLTY
FEFTTLAIIHAFAAAGLDAIILEVGLGGRLDAVNVIDTDCAIVTSVDIDHTQYLGHTREE
IGFEKAGIFRPGVPAICGDPMPPKSLVAHAEAVGAELWLVGRDYHFHAAKGQERQQWDWS
GGGRKLNGLGYPALRGANQLLNAAAALAALQAMRPRLPVSAQEVRNGLAFVELPGRFQVL
PGRPAVILDVAHNPHAAATLGQNLENMGFFRYTYAVFGAMQDKDIAGVLQHVADKVDHWC
LCDLPTERAASAADLLAKLDAGGFRPGPDATAACFSSPEAAFRDAIERATENDRILVFGS
FYTVAGVMAYRATQAN
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgcctgtcttccatacgctccccgaatggcttgcccatctcgaaaccgcccatcccgtg
ggcatcgatatgggcctggcgcgcatcacgcgcgtgaaggaggccctcgggctgcgcatc
gacgctgtggtgttcacggtgggcggcaccaacggcaagggctctacctgcgcgatgcta
gagcgcatcctgctggaggccggctacaaggtgggctgccatacctcgccgcacctgatc
tcgttcaacgagcgcgcccgcatcaatggcgagatcgccaccgatgcgcagctgctgccg
catttcgaggcggtcgagcgcgcacgcaacagctttgccgacccggtcagcctgacgtac
ttcgagttcaccacgctggcgatcatccatgccttcgccgcggccgggctggacgcgatc
atcctggaagtaggcctgggcgggcggctggacgcggtcaacgtaatcgataccgactgc
gccatcgttaccagcgtcgatatcgaccatacccagtacctgggccatacgcgcgaggaa
atcggcttcgagaaggccggcatcttccgcccgggcgtgcccgcgatctgtggcgacccg
atgccgcccaagtcgctggtggcgcacgccgaagcggtcggcgccgagttgtggctggtg
gggcgcgattaccatttccacgccgccaagggccaggagcgccagcaatgggactggagc
ggcggcgggcgcaagcttaacggcctgggctacccggcgctgcgcggggccaaccagctg
ctcaacgcggcggcggcgctggccgcgctgcaggccatgcgcccgcgcctgccggtcagc
gcacaggaagtgcgcaacgggctggcctttgtcgagctgccgggacgcttccaggtgctg
ccggggcgcccggcggtgattctggacgtggcgcacaatccgcatgcggcggccacgctg
gggcaaaacctggagaacatggggttcttccgctacacctatgcggtgttcggcgcgatg
caggacaaggacatcgccggggtgctgcagcacgtggccgacaaggtcgaccactggtgc
ctgtgcgacctgccgaccgagcgcgccgccagtgccgcggacctgctggccaagctggac
gcgggcggattccgccccgggccggacgccaccgcggcctgcttttccagccccgaggcg
gcattccgcgatgccatcgagcgagccaccgagaatgatagaattctggtcttcggatcg
ttctataccgtcgccggcgtgatggcctatcgtgccacgcaggctaactga
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