Cryptococcus neoformans var. neoformans JEC21: CNF04450
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Entry
CNF04450 CDS
T00243
Name
(RefSeq) pyruvate dehydrogenase E1 component alpha subunit, mitochondrial precursor, putative
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cne
Cryptococcus neoformans var. neoformans JEC21
Pathway
cne00010
Glycolysis / Gluconeogenesis
cne00020
Citrate cycle (TCA cycle)
cne00620
Pyruvate metabolism
cne00785
Lipoic acid metabolism
cne01100
Metabolic pathways
cne01110
Biosynthesis of secondary metabolites
cne01200
Carbon metabolism
cne01210
2-Oxocarboxylic acid metabolism
Module
cne_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cne00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CNF04450
00020 Citrate cycle (TCA cycle)
CNF04450
00620 Pyruvate metabolism
CNF04450
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CNF04450
Enzymes [BR:
cne01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CNF04450
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
3258041
NCBI-ProteinID:
XP_571697
UniProt:
Q5KES4
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All DBs
Position
6:join(1291574..1291630,1291677..1291775,1291846..1291953,1292032..1292337,1292387..1292635,1292685..1293032,1293094..1293168)
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AA seq
413 aa
AA seq
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MSFALRARGLRAATRSLGAKPLRSTLPQVRYVQIDADKSSPMHDLPASGSEPFKVQLHAD
SFHSYRCDAPPPETTVTKDELINMYRTMVQMRRMEQAADALYKQKLIRGFCHLAIGQEAV
SVGMETAITGQDRVITSYRCHTFAVLRGGTIKGVIAELMGRKDGMSFGKGGSMHIFTPSF
FGGNGIVGAQVPVGAGVALAQKYNKEKAATFALYGDGAANQGQVFEAFNMAKLWNLPCVF
VCENNKYGMGTSAERSSMNTQFFTRGDQIPGLQVNGMDILAVREATKWAREWATSGKGPL
LVEFVTYRYGGHSMSDPGTTYRTREEVQQMRSSQDAIAGLKKYILEWGATDEASLKAIDK
AAKEEVDAAVEEAKQSPFPDQVEFWSDIYYKGSEPTHMRGREKEEVHYYNKSA
NT seq
1242 nt
NT seq
+upstream
nt +downstream
nt
atgtccttcgccctccgtgcccgtggcctccgcgccgccacccgctccctcggcgccaag
ccgctccgttccaccctcccccaggtgcgctacgtgcagatcgacgccgacaagtcctcc
cccatgcacgacctccccgcctccggttccgagcctttcaaggtccagctccacgccgac
tcgttccactcttaccgatgcgatgccccgcctcccgagaccaccgtcaccaaggacgag
ctgatcaacatgtaccgcaccatggtccagatgcgacgaatggagcaagccgccgacgcc
ctttacaagcaaaagcttatccgaggcttctgccaccttgccatcggccaggaagccgtt
tccgtcggcatggagaccgccatcaccggccaggaccgggtcatcacctcttaccgatgc
cacactttcgccgtcctccgaggtggtaccatcaagggcgtcattgccgagctcatgggc
cgaaaggacggtatgtctttcggtaagggtggttctatgcacatctttactccgtcattc
tttggtggtaacggtatcgtcggtgcccaggtccccgtcggcgccggtgtcgcccttgcc
caaaagtacaacaaggagaaggctgctacgtttgcgctctacggtgacggtgccgctaac
caaggccaagtctttgaggctttcaacatggccaagctctggaacctcccctgtgtcttt
gtctgtgagaacaacaagtacggtatgggtacttctgccgagcgatcttccatgaacact
cagttcttcacccgtggcgaccagatccccggtctccaggttaacggtatggacatcctc
gctgtccgagaggccaccaaatgggccagggaatgggccacgtccggcaagggtcccctc
ctcgtcgagtttgtcacctaccgatacggtggccactccatgtccgaccccggaaccacc
taccgaacccgagaagaagtccagcaaatgcgatcttcccaggacgccattgccggcttg
aaaaagtacattctcgaatggggagcgaccgatgaggcgagcttgaaggcgattgataaa
gccgccaaggaagaggtggatgccgctgtcgaggaggccaagcagagtcctttccctgac
caggtcgagttctggagtgacatctactacaagggttccgagcccactcatatgcgcggc
agggagaaggaggaggtccactactacaacaagtctgcttaa
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