Cryptococcus neoformans var. grubii H99: CNAG_00237
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Entry
CNAG_00237 CDS
T08175
Name
(RefSeq) 3-isopropylmalate dehydratase, large subunit
KO
K01702
3-isopropylmalate dehydratase [EC:
4.2.1.33
]
Organism
cng
Cryptococcus neoformans var. grubii H99
Pathway
cng00290
Valine, leucine and isoleucine biosynthesis
cng01100
Metabolic pathways
cng01110
Biosynthesis of secondary metabolites
cng01210
2-Oxocarboxylic acid metabolism
cng01230
Biosynthesis of amino acids
Module
cng_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cng00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CNAG_00237
Enzymes [BR:
cng01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CNAG_00237
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
Aconitase_C
Motif
Other DBs
NCBI-GeneID:
23884063
NCBI-ProteinID:
XP_012046605
UniProt:
J9VG96
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Position
1:620496..623276
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AA seq
763 aa
AA seq
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MPAPITTPRTLYDKVFDDHVVHSGEGDTLIYIDRHLVHEVTSPQAFEGLRNAGRKVRRPD
CTLVTVDHNIPTISRKNFKNVNTFIGEADSRAQVAALEDNVKEFGLTYFGMSDKRQGIVH
IIGPEQGFTLPGTTVCCGDSHTSTHGAFGALAFGIGTSEVEHILATQTLPQAKSKNMRIN
VEGILAEGVSSKDIVLHIIGVIGTAGGTGCVIEFSGSTIRALSMEARMSICNMAIEGGAR
AGMIAPDEITFEYLKGRPLSPREGEEWDKAVEYWKTLKTDPGAKYDIEVEIKAEDIVPTL
TWGTSPQDVVPITGVVPNPDDFPEAQRGNIVRALEYMGLTSGTPMEKVKIDKAFFGSCTN
GRIEDMRSAARVILASQKNGGPSKVADGVYAMIVPGSGLVKQQAEAEGLDVIFKKAGFDW
REAGCSMCLGMNPDQLKPGERCASTSNRNFEGRQGAGGRTHLMSPAMVAAASLTGYLTDV
RTLMGSHVNDDDGLKITSYFDYLTPVEVPARSAEPTEETEEGKTPVKAAAAGSAGLPKFN
ILRGIAAPMWEANIDTDKIIPKQFLKTLLRTGLGKALFWPLRYDVQTNEEIPDFVLNKEP
YRHASIIVCTGPNFGCGSSREHAPWALNDFGIRCVMAPSFGDIFRTNCFKNGMLPLQLPQ
ADLDTLYEDASAGLEITVDLENQVIIRPNGKPSIPFSVDPFRRHCLINGLDDIGLTLVHR
DEIEKFEEKRTAVWPWLDGVGYAKKGQKVIAVPVKKGVRKTDW
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atgcctgctccgataaccactcctaggactctttatgacaaggtctttgacgatcacgtc
gtacactccggggaaggcgatacccttatctacatcgatcgtcatctcgttcacgaagtt
acttctcctcaagctttcgaaggtttgagaaatgctggacgaaaagttcgtcgaccggac
tgtacacttgtcactgtcgaccacaatattcccaccatctctcgtaagaacttcaagaat
gtcaacactttcattggtgaggcggacagtcgggcgcaggttgccgccctcgaagacaat
gtgaaggagtttggccttacatacttcggtatgagcgacaagcgacaaggcattgttcac
atcatcggtccagaacaaggattcactcttcccggtacaactgtttgctgcggtgactct
cacacgtccacccacggtgcttttggtgcccttgcttttggtatcggcacttctgaagtg
gaacacatcctcgctacacaaactctcccccaagccaagtctaagaacatgcgaatcaat
gttgagggtattcttgccgagggtgtgtcctccaaagacattgttcttcatatcattggt
gtaatcggtactgctggtggtactggctgtgtcattgagttctctggctcaacaatccga
gcgctcagtatggaggcaagaatgtctatctgtaacatggccattgaaggaggtgctagg
gccggcatgatcgcccctgatgagattactttcgaatatctcaagggacgtcctcttagc
cctagagaaggtgaggaatgggataaggcagtggagtactggaaaaccctgaagacggat
cccggagccaaatacgatatcgaggttgagatcaaggctgaagacatcgtgcctaccctc
acttggggtacttctcctcaggatgttgtacctatcactggtgttgttcctaaccctgac
gatttccccgaagctcagcgtggtaatattgttcgggctctcgagtacatgggtcttacc
tccggtacccctatggagaaggtcaagattgacaaggctttcttcggctcttgtaccaac
ggtcgtattgaagacatgcgctctgctgctcgtgtcatccttgcctcgcagaaaaatggt
ggaccttctaaggtcgcggatggtgtctacgctatgatcgttcctggttctggtttggtt
aagcaacaagcggaagccgaaggtcttgatgtcattttcaagaaggcgggctttgactgg
cgagaagctggttgctccatgtgtcttggtatgaacccggaccagctcaagcccggagag
cgatgcgccagtacctcgaacagaaacttcgaaggtcgacaaggcgctggtggccgaact
catctcatgtcccctgcaatggtggccgctgcttctcttactggttacctcaccgatgtt
cgaacactcatgggctcccatgttaatgatgatgatggactcaaaatcacatcatatttc
gactatctcacacctgtcgaagtgccggctcgatccgcggaacctactgaggagaccgaa
gagggtaagactcctgtcaaggccgccgctgctggctctgccggcttgcccaagtttaac
attcttcgaggcatcgctgcccccatgtgggaggccaacatcgacaccgacaaaatcatc
cctaagcagttcttgaagactctccttcgtactggtctcggaaaggctctcttttggccc
cttcgatacgacgttcagaccaatgaagagatccctgatttcgtgctcaacaaggagcct
tataggcacgctagtatcattgtctgcactggtccgaacttcggttgcggttcttctcgt
gaacatgctccttgggctcttaacgatttcggtattcgatgtgtgatggcgccatccttt
ggcgacatcttcagaaccaattgcttcaagaacggtatgcttcctcttcagcttccccag
gccgatctcgataccctctatgaagatgcttcagctggcctcgagatcacggtcgatctt
gagaaccaagtgatcatccgacccaacggcaagccatccattcctttctctgttgacccc
ttccgacgccattgccttattaatggtctcgatgacatcggtcttacccttgtccaccga
gatgaaattgagaagtttgaagagaagaggaccgccgtatggccttggcttgacggtgtt
ggatatgccaagaagggacagaaggtcatcgctgtgccggttaagaagggcgtcaggaag
acggactggtaa
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