Cobetia sp. AM6: CLAM6_10190
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Entry
CLAM6_10190 CDS
T08724
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cobe
Cobetia sp. AM6
Pathway
cobe00790
Folate biosynthesis
cobe01100
Metabolic pathways
cobe01240
Biosynthesis of cofactors
Module
cobe_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
cobe00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CLAM6_10190 (folC)
Enzymes [BR:
cobe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CLAM6_10190 (folC)
6.3.2.17 tetrahydrofolate synthase
CLAM6_10190 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BBO55708
UniProt:
A0A5K7Y3Y4
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Position
1220415..1221953
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AA seq
512 aa
AA seq
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MAEQGSAPASCSTDEVLQSSSLPPLNAASWQLSPLHDAVPRGLSLDEWLTRLEHQHPVSI
DMGLARVLCVARRLGLVGAGARRLGGRIITVAGTNGKGSTVAMLEALGRAHGLSTATYTS
PHLLHYNERLSFNGHDVSDAALVTAFEQVDSARHSGLSASGEPVDDEGVISLTYFEAGTL
AGLWLIAQQQPQLAILEVGLGGRLDAVNIIDCDVAMIITVAQDHAAFLGTDLENIGFEKA
GILRAGKPAVFGSDVLPSSCAEHARSLGVTPQVLWQDFRWQVAADLVNGSVNGSVNGSVN
GSVDGSTDHSATSQWQWQRLSAPALTFDALPDPGLPRDNAASALNALVEAGIELNAECVQ
QAMARVKLKGRMQWLSRHGRDWCLDVGHNPHAASYLASRLAAHDLRCARDPATRPRRALL
AMLGDKDAAGVIQALAPVVDGFVVATLDGERSRQASELAAVVRHCGGEVLAECETVTAAA
EWLARETSAGEVLVCGSFFTVGEALMWLGAQA
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atggctgagcagggctccgccccggcaagctgcagcaccgatgaggtgctgcagtcttcc
tcactccctccgctgaatgccgcttcgtggcagctttcccccctgcatgatgccgtgccg
cgtggcctctcgctggatgagtggctgacgcgtctcgagcatcagcaccccgtcagtatc
gatatgggccttgcccgagtgctgtgcgtggccaggcgcctcggtctggtcggggcgggt
gcgcgtcggctcggtggccgcatcattaccgtggcgggcaccaacggcaagggctcgacg
gttgccatgctcgaggcgctggggcgtgcccacgggctgagcaccgccacctatacctct
ccgcacctgctgcattacaacgagcgtctgagcttcaatggtcacgacgtcagtgatgcg
gcattggtcacggccttcgagcaggtcgattccgcgcgccactccgggctgtcggccagt
ggtgagccggtggatgacgagggcgtgatcagcctgacctacttcgaggccggcacgttg
gccgggctatggctgatcgctcagcagcagccgcagctcgcgattctggaagttggcctg
ggtgggcgtctggacgcagtcaacatcatcgattgtgatgtcgcgatgatcatcacggtc
gcacaggatcatgccgcgtttcttggcaccgacctcgagaacatcggcttcgagaaggcc
gggattctgcgcgccggcaagccggccgtgttcggctcggatgtgctgccgtccagttgc
gcggaacatgctcgctcgctgggtgtcacgccgcaggtgctatggcaggactttcgctgg
caggtcgcggctgatcttgtgaatggcagtgtgaatggcagtgtgaatggcagtgtgaat
ggcagtgtggatggcagcacggaccattcggctacctcgcaatggcaatggcagcgcctg
tcagcgccggcactgacgttcgatgcgctgccagacccgggcttgccgcgggacaatgcg
gccagtgcgctgaatgcgctggtcgaggccggtatcgagctcaacgccgaatgcgtgcag
caggccatggcgagagtcaagctcaaggggcgcatgcaatggctgagccgtcacgggcgt
gactggtgtctggatgtcggccataacccgcatgccgcgagttatctggccagtcgtctt
gccgctcatgacctgcgttgcgcgcgggatcctgccactcggccgcggcgggcgttgctc
gccatgctgggcgacaaggatgccgctggcgtgattcaggcgctggcaccggtggtggac
ggcttcgtcgtcgccaccctggatggcgagcgtagccgccaggccagtgagcttgccgcc
gtggtccgccactgtggtggtgaggtgctggcagagtgcgagacggtcaccgctgcagcc
gaatggttggcacgcgagacgagcgctggagaagtattggtctgtggttccttcttcacg
gtcggtgaagcattgatgtggctcggcgcccaggcctga
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