Corynebacterium pseudotuberculosis 3/99-5: Cp3995_0276
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Entry
Cp3995_0276 CDS
T01689
Symbol
hemD
Name
(GenBank) Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cpl
Corynebacterium pseudotuberculosis 3/99-5
Pathway
cpl00860
Porphyrin metabolism
cpl01100
Metabolic pathways
cpl01110
Biosynthesis of secondary metabolites
cpl01120
Microbial metabolism in diverse environments
cpl01240
Biosynthesis of cofactors
Module
cpl_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cpl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Cp3995_0276 (hemD)
Enzymes [BR:
cpl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Cp3995_0276 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Cp3995_0276 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
DPBB_1
Motif
Other DBs
NCBI-ProteinID:
AEX38749
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Position
287374..289062
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AA seq
562 aa
AA seq
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MSSTPQPTPVTPAPEGKVIFVGAGPGNPDLLTVRAREVLSHTAFAVVDAEVLPGVRSVVA
RELDVPMDKVQAAEEEYERLCAEAKEAGARRKPQRPDAPTAAEITEVDDDVPVVEVVEKL
KELLSSGEDVIRLVQGNPLSCDRTLEEISAVKQAGLEFHVVPGMSLPATVPAFAGIALGS
SYTETDVTGEDVDWEQLAAAPQPLVLQATKEDLPTIAAELKSRGIEASTPVTVTARGTTR
LQRSFDISLGALHKLDGDLAGTLVVTLGKAADERTKYSWWENRSLFGWRVLVPRAKEQAG
SMSALLAAQGAIPQEVPTISVEPPRNPAQMEKAVKGIVEGRYQWVIFTSVNAVKSVREKI
GSFGLDARAFAGVRIGAVGTKTAKAIRELGITPELLPPRNRQNAAGLVSVFPEYVEDLDP
VGRVLLPRADIATDVLVEGLEGLGWEVDDVVAYRTVRAAPPSAEVRDMIKSGGFDAVCFT
SASTVKNLVGIAGKPHQRTIIACIGPMAAAAAKELGLRVDVIPEVADVPHLINGLATHVA
QLRAAGQLPPPRKKRRARKNRE
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgagttcgactccgcaacccaccccggtaacccctgcaccggagggaaaagtgatcttt
gtaggagcaggaccaggaaaccctgatctgctcaccgttcgcgcccgcgaagttctcagc
cataccgcttttgccgtagtagatgcagaagttctaccgggggttcgctcagtggttgca
cgtgaactcgatgtgccgatggataaagttcaggcggctgaggaagaatacgagcggctg
tgcgcggaagcaaaagaagctggtgcgcgccgtaaaccgcagcgcccggacgccccgact
gccgctgagattacagaagtagacgacgacgttcctgtagtagaggtagtggaaaagctt
aaggagcttttgtccagcggggaagacgttattcgcctggtgcagggaaaccccttgtca
tgtgaccgaaccctggaagaaatttctgcggtcaagcaggccggactggagttccacgtg
gttcccggcatgtccttgccggcgaccgttcctgcttttgcgggtatcgctctgggctct
tcttatacagaaaccgatgtaactggggaagacgtagattgggaacagcttgctgcagca
cctcagccgctggttttgcaggcaactaaagaggatctgcctacaatagccgcagagtta
aaatctcgtgggatagaggcatcgaccccggtgacggtgacagctcgcgggacaacacgc
ttgcaaagaagttttgatattagtttgggcgccctgcacaagttggacggggacctcgcc
ggaaccctcgtggttactttaggcaaagcagcggatgaacgtaccaagtattcttggtgg
gagaaccgttcgctctttggttggagagtgctggtcccccgtgcaaaagaacaagccgga
tcaatgagtgcattgttggctgctcagggggcaatcccgcaagaagttcccacaatctct
gtggagccgccacgtaatcctgcgcaaatggagaaggccgttaaagggatcgtggaaggc
cgctaccaatgggtgatttttaccagcgtcaacgcagtgaaatccgtgagagagaaaatc
ggttccttcggactcgatgctcgtgcctttgctggcgtgcgcattggagcggtaggaaca
aaaactgctaaggccatccgtgagcttggaatcacgccggagttgctccctccgagaaat
cggcaaaacgctgcaggtttagtgtcagtgttcccggagtatgtggaagaccttgatcca
gtcggacgggtcctcttgccccgggcggatattgcaacggacgtcctggtggaaggctta
gaaggccttggctgggaggtcgacgatgtggtggcgtatcgcacggtacgggccgccccg
ccgagtgcagaagtgcgcgacatgattaaaagtggcggttttgacgctgtgtgctttacc
tctgcatccacggtaaaaaatctggtgggcattgctgggaaaccacatcagcgcacaatc
attgcatgcattggtccgatggcggcggcagcggcaaaagaattaggcctgcgggtggac
gtgatccccgaggtagcggatgttcctcacttgattaatggtcttgctacccacgtggca
caactgcgcgcagctggccagctgccgcctcctaggaagaagcggcgcgcccgaaaaaat
cgcgagtaa
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