Cavia porcellus (domestic guinea pig): 100135594
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Entry
100135594 CDS
T07777
Symbol
Pde4a
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00230
Purine metabolism
cpoc01100
Metabolic pathways
cpoc04024
cAMP signaling pathway
cpoc04928
Parathyroid hormone synthesis, secretion and action
cpoc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100135594 (Pde4a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100135594 (Pde4a)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100135594 (Pde4a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100135594 (Pde4a)
Enzymes [BR:
cpoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100135594 (Pde4a)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
100135594
NCBI-ProteinID:
XP_003460919
Ensembl:
ENSCPOG00000024714
LinkDB
All DBs
Position
Unknown
AA seq
850 aa
AA seq
DB search
MEPPAATSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERP
PHRPIERADAVDTSDRPGLRTTRMSWPSSFHGTSTSSGSAGGGSGRRFEAENGPTPSPGR
SALDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSHKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREPQEAPRQRPCQQLPPPVPHLQPMSQITGVKRLSHNSGLNNASIPRFGVKTD
QEELLAQELENLSKWGLNIFCVSDYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMVTYVL
TLEDHYHSDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQDILDTLEENRDWYYSAIRQSPSPPPEEEPSGLRHCAPPEKFQFELTLEEEEEEE
ACLAQDSMKTLGSFRVEELGKVMGQEAETGHLPRGLASVCVVPPMAQEESVDAGSCDLSL
ESPLRPALRTQSTPEESPGPPGLPSMAAEVGAQRDHQAATRACCTCTGTSWEDPAILPVP
SGWESGGDPP
NT seq
2553 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccacctcggagaggagcctgtctctatctctgcccgggccccgg
gagggccaggccaccctcaagccgccccctcagcacctgtggcggcagccgcggaccccg
atccgtatccagcagcgcggctactccgacagcgcggagcgctcggagcccgagcggccg
ccacaccggcccatagaacgcgctgacgccgtggacaccagcgaccggcccggcctgcgc
acgacccgcatgtcctggccttcgtccttccatggcaccagcacaagcagcggcagcgcg
ggcggaggcagcggcaggcgcttcgaggcagaaaatgggccgacgccgtcccccggccgc
agcgccctggactcgcaggcgagcccgggcctggtgctgcacgccggggcagccaccagc
cagcgccgggagtccttcctctatcgctccgacagcgactacgacatgtcccccaagacc
atgtcccgcaactcatcggtcaccagcgaggcgcacgcggaggacctcattgtaacgccc
ttcgcccaggtgctggccagtctccgcagcgtccgaagcaacttctcgctcctgaccaat
gtgcccattcccagtcacaagcggtccccactgggaggccccacccccgtctgcaaggcc
acactgtcagaagagacgtgtcagcaactggcccgggagaccctggaggagctggactgg
tgcctggagcagttggagactatgcagacctaccgctctgtcagcgagatggcatcacac
aagttcaagaggatgctaaaccgggagctcacacacctgtcagaaatgagcaggtcggga
aaccaggtctcagagtacatttccacgacattcctcgacaaacagaatgaagtggagatc
ccgtcaccaacgatgaaagaccgagagccccaagaagcaccccgacaaaggccctgccag
cagcttccacccccagtgccgcatttgcagcccatgtcccagatcacgggggtgaagagg
ctgtcgcacaacagcggcctgaacaacgccagcatcccacgcttcggggtgaagacggat
caggaggagctcctggcccaagagctggagaatttgagcaaatggggcctgaacatcttc
tgtgtgtctgattatgccggaggccgctctctgagctgtatcatgtacacgatattccag
gagcgggacttgctgaagaaattccacatccctgtggacacgatggtgacatacgtgctg
acgctggaggaccactaccactccgacgtggcctaccacaacagcctgcacgcggccgac
gtgctgcagtccacccacgtactgctggccacgcccgccctggatgcggtattcacagac
ctagagattctcgcagccctcttcgcagccgccatccatgacgtggaccaccctggggtc
tccaaccagttcctcatcaatacaaactcggagctggcgctcatgtacaacgatgagtcg
gtgcttgagaaccaccacctggccgtgggcttcaagctgctgcaggaagagaactgcgac
atcttccagaacctcagcaagcgccagcgacagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaagcacatgaccctcctagctgacctgaagactatggtg
gagaccaagaaggtgacaagctcgggagttctcttgctggacaactactccgaccgcatc
caggtccttcggaacatggtacactgtgcagacctcagtaaccccaccaagccgctggag
ctgtaccgccagtggactgaccggatcatggccgagttcttccagcaaggcgaccgagaa
cgagagcggggcatggagatcagtcccatgtgtgataagcacacagcctccgtggagaag
tcacaggtgggtttcatcgactacatcgttcaccctctgtgggagacctgggccgacctg
gtgcaccctgatgcacaggacatcctggacacgctggaggagaaccgggactggtactat
agcgccatccggcaaagcccgtcaccaccgcccgaggaggagcccagcgggctccgccac
tgcgccccacctgagaagttccagtttgagctgacgctggaggaggaggaggaggaggag
gcatgcctagcccaggattcgatgaaaactctgggatcgttcagggttgaggagctgggc
aaggtcatgggccaggaggccgagacagggcatttgccacggggtttggcttcggtgtgt
gtggtcccccctatggcgcaggaggaatctgtggatgctggaagctgtgacctgtctctt
gaaagcccccttcggcctgccttgaggacccagtccacgccagaggagtccccgggcccc
ccgggcctcccctccatggcggccgaggtgggggcccaaagagaccatcaggctgccacg
agggcttgctgcacctgcacagggacatcgtgggaggacccagccatcctcccggttccc
agcgggtgggagtcaggtggggaccctccctga
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