Cavia porcellus (domestic guinea pig): 100721619
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Entry
100721619 CDS
T07777
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00010
Glycolysis / Gluconeogenesis
cpoc00020
Citrate cycle (TCA cycle)
cpoc00620
Pyruvate metabolism
cpoc00785
Lipoic acid metabolism
cpoc01100
Metabolic pathways
cpoc01200
Carbon metabolism
cpoc01210
2-Oxocarboxylic acid metabolism
cpoc04066
HIF-1 signaling pathway
cpoc04922
Glucagon signaling pathway
cpoc05230
Central carbon metabolism in cancer
cpoc05415
Diabetic cardiomyopathy
Module
cpoc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100721619 (Pdha2)
00020 Citrate cycle (TCA cycle)
100721619 (Pdha2)
00620 Pyruvate metabolism
100721619 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100721619 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100721619 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100721619 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100721619 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100721619 (Pdha2)
Enzymes [BR:
cpoc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100721619 (Pdha2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100721619
NCBI-ProteinID:
XP_023421796
LinkDB
All DBs
Position
Unknown
AA seq
485 aa
AA seq
DB search
MVRRSCVLGRIAPSSRPLTTGTRAQAAGSTERTWGCGFWCGVSRWGAPPQVYQRGGAPAP
FSALRSGPQDAWIRAVSRRLATQARGVSKYRGVRTLSLAGSRRRRCWAQQALSWGVAGAP
GARGLLASRHLRIKTLRPLPPGGGPTGTAELSREDALRLYRSMQKVRRMELAADQMYKQK
LIRGFCHLCDGQEACCVGLEAGITPSDHVITSYRAHGVALARGLSVRAILAELTGRRSGC
AKGKGGSMHMYARHFYGGNGIVGAQVPLGAGVALACQYLGTGSVCLTIYGDGAANQGQVA
EAFNMAALWKLPCVFICENNRYGMGTSAERSSAATEYYKRAYFLPGLRVDGMDVLCVREA
TRFAADHCRSGKGPLVMELLTYRYHGHSMSDPGISYRSREEVQAVRSKSDPIMLLQEKMV
SSDLSSVEELKEINSEVKKEVAEAVQFATSDAEPSLDVLGHHIYCSNPPFEVRGANQWIK
FKSIS
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atggtcaggcgatcctgtgtgctgggccgcattgcgccgtcctccaggcctctcaccacg
ggaactcgggcccaggctgcggggtccacggagcggacctggggctgcgggttctggtgt
ggagtctctaggtggggcgcccctccacaggtgtaccagcgaggcggggcaccagctccc
ttctcagccttgcggtcaggtcctcaggatgcgtggataagggcagtctcgcgacgcctg
gccactcaggctcgcggggtcagtaaatatcgcggagtcaggacactgagtctcgcggga
tcacgacgacgacgatgctgggcgcagcaggcactctcgtggggcgtggccggcgcgccg
ggcgctcgtggccttctcgcgagccgccaccttcgcatcaagaccctgcgacctctaccg
cctggaggagggcccaccggcacggcggagctgagccgcgaggacgcgctgcgcctctac
cgcagcatgcagaaggtgcgccgcatggaactcgcagccgaccagatgtataagcagaag
ttgatccgaggcttctgccacctgtgcgatgggcaggaagcgtgctgcgtggggctggag
gcgggcatcacgccgtcggaccacgtcatcacatcctaccgggcgcacggcgtggcctta
gcgcgagggctgtcggtgcgcgccatcctggctgaactcacagggcgccgcagtggctgc
gcgaagggcaagggcggctccatgcacatgtacgcgcgccacttctacggcggcaacggc
atcgtaggcgcgcaggtgcccctgggcgcgggcgtggcattggcctgccagtatctaggc
actggcagcgtgtgcttgacgatatacggtgatggcgcagccaaccagggccaggtggcc
gaggccttcaacatggcggcgctgtggaagttgccctgcgtctttatttgtgagaacaac
cgctatggcatgggcacctcggcagagcgctcgtcggccgccaccgagtactacaagcgc
gcctacttcctgcccggcctgcgcgtagatggcatggacgtgctttgcgttcgcgaggcc
actcgcttcgctgctgaccactgtcgctcagggaagggcccgctggtgatggagctgctg
acctaccgctaccacgggcacagcatgagcgacccgggcatcagctaccgctcccgggag
gaggtgcaggccgtgaggagcaagagtgatcccatcatgcttctgcaggagaagatggtg
agcagcgatctcagcagtgtggaggagctgaaggagatcaactccgaagtgaagaaagaa
gtggcagaggcggtccagttcgccacctcggatgcagaaccatctttggatgttttaggc
caccatatctactgcagcaacccaccgtttgaagttcgtggtgctaatcagtggatcaag
tttaaatccatcagttaa
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