Thermoclostridium stercorarium subsp. stercorarium DSM 8532: Clst_0640
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Entry
Clst_0640 CDS
T02527
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
csd
Thermoclostridium stercorarium subsp. stercorarium DSM 8532
Pathway
csd00790
Folate biosynthesis
csd01100
Metabolic pathways
csd01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
csd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Clst_0640
Enzymes [BR:
csd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Clst_0640
6.3.2.17 tetrahydrofolate synthase
Clst_0640
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGI38734
UniProt:
L7VMK0
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Position
709945..711234
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AA seq
429 aa
AA seq
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MNYENAIEYIESLEGLGSRSGLKRIKALTERLGNPQEHLKFIHVAGTNGKGSTSAFISSI
LSCAGYSTGLYISPHLQRYNERISINGQEISDEELFKYTWRIKNVIDEMVKEGLEHPTVF
EVITAMAFLYFYEKGCDAVVLEVGLGGRLDATNVISDSLVSVITKISLDHTEILGNTVAE
IAYEKAGIIKQNGRVVTYPQEKAALDVIESVCRQRNAELYCADPGEFEKAELSPGLLHLV
HPRYGNIETSIVGVHQVYNASVALKTVEVLRQAGFKIEDGDVVKGFKTASWPGRFELLAR
NPDFYIDGGHNPDGVRSFVETYKKIYPDRKATIIFGVMKDKDYDAMLRELSAISKRFIAV
TPDSPRALDAGSLVKVMSKYCKNVEFSDTIEAAVEKALSDATGEDVIAALGSLYYIGQVR
GKFQISAQK
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
atgaattacgaaaatgcaatcgaatatatagaaagccttgaggggcttggaagcaggtcc
ggtcttaaaagaattaaagctcttacagaaaggctgggcaatccgcaggagcatcttaaa
ttcatacacgttgcaggtacaaacggaaaaggctctacttctgcctttatatcctctatt
ctttcatgtgcgggatactcaacaggtttatatatctctccgcatcttcagcggtataat
gagagaatcagtattaacgggcaggaaataagcgacgaagagttatttaaatatacctgg
agaattaaaaacgtaatcgatgaaatggttaaggaagggcttgagcatccaaccgttttt
gaagtgattacggcaatggcttttctttacttttatgaaaaaggatgcgatgccgtagtt
cttgaggttggattaggagggcggctggatgctacgaatgtcatttccgattcgctggta
tcggttataaccaaaatttcccttgaccataccgaaattctgggaaacaccgtcgctgaa
attgcttatgaaaaagcaggcattataaaacagaacggaagagtggtaacatatccgcag
gaaaaggcggctttggacgttattgagtctgtatgcaggcagagaaatgcagagttatat
tgtgcggaccccggagagtttgaaaaagccgaattaagccccggtttactgcatttagta
cacccgcgctacggaaatatagaaacatcaattgtcggagtacaccaggtttacaatgcc
tctgtcgctttaaaaacggttgaagttctgagacaggcgggatttaagatagaagacggt
gatgttgtgaaaggctttaaaactgcgtcatggccgggaaggtttgaacttttggcaaga
aatcccgatttctatatagacggaggtcataaccccgacggtgtccgttcctttgttgaa
acgtacaaaaagatttatcctgacagaaaagccacgataattttcggtgtcatgaaggat
aaggattatgacgcgatgcttagagagctttcagcgatatcgaagcgctttattgctgta
actcctgactctccaagggcgcttgatgcaggaagtcttgtaaaagtaatgtcaaagtat
tgtaaaaatgtagaatttagtgatacaatagaggcagcagtggaaaaagcgctttcggac
gctaccggggaagatgttatagcagcactggggtcgctgtattatataggccaggtacgt
ggcaaatttcaaatttctgcgcaaaaatga
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