Thermoclostridium stercorarium subsp. stercorarium DSM 8532: Cst_c11710
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Entry
Cst_c11710 CDS
T02440
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase PurL
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
css
Thermoclostridium stercorarium subsp. stercorarium DSM 8532
Pathway
css00230
Purine metabolism
css01100
Metabolic pathways
css01110
Biosynthesis of secondary metabolites
Module
css_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
css00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Cst_c11710 (purL)
Enzymes [BR:
css01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Cst_c11710 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AGC68167
UniProt:
L7VN53
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Position
1278301..1282056
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AA seq
1251 aa
AA seq
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MAVRRIYVEKKPGFDVKARKLMEEITEYLKIKGIENVRIINRYDVEGISDEDYEKAKTLI
FSEPPVDYVYEEELPLRDNERVFAVEYLPGQYDQRADSCAQCIQLLSGTERPEIRVATVI
AIGGDISDKDFEKIKEYYINPIESREAALTKPETLREEYAVPDMVDVIKGFTLMDEEALE
KLITELGFAMSVEDLVFCREYFKNTEKRDPTVTELRVIDTYWSDHCRHTTFLTEIEEVSF
DKGSVSEKISEVYNLYLETRKKVYKDREKPVCLMDIATLAMKELKREGYLNDLDESDEVN
ACSIVVDVDIDGRKEPYLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRAYVYQAM
RVTGSGDPRTPVTQTLPGKLPQRVITRKAALGYSSYGNQVGLATGQVNEIYHEGYVAKRM
EIGAVIAAAPKSNVVRKKPEAGDVVILLGGRTGRDGCGGATGSSKAHTEESLTKCGAEVQ
KGNPPTERKIQRLFRNPEVTRLIKKCNDFGAGGVSVAIGELADGLEIDLDAVPKKYQGLD
GTELAISESQERMAVVVAKEDAERFIALSAEENLEATIVARVTDTNRLVMKWNGEKIVDI
SREFLNTNGVKRRTKVTVKEPGNIFDNCGQKDGRDFSENFKNNLLRLNVCSQKGLIEMFD
STVGAGTVLMPLGGKNQLTPAEGMAAKIPVANGETRTGTLMSFGFDPDISSKSPFHGAVY
AIVESVAKIVAMGGDHRKVRLSLQEYFEKVGDDPVKWGKPFSALMGAFYAQMKMKIPAVG
GKDSMSGTFKDLNVPPTLVSFAVSVCDVTKVISPEFKNPRSTVAVVKIKRDELGLPDFEH
LDRTYERLHGLITENRIVSACTVKCGGIAEAICKMAFGNDIGFSSRTGISPEKWFLPDYG
NIVVEVPGGHDIDELFEGLDYEVLGETTDEPVISVGNEKWNLDELKELWQSPLESIFPTK
VKEEERKPMNIMFDGMKPVHHSGTFAKPRVFIPVFPGTNCEYEAAMAFERAGAVTDIFVM
KNLTPADIKESVKIMKEKIKNSQIIMLSGGFSAGDEPDGSGKFIATVFRNPELAEAVMEF
LKVRDGLMLGICNGFQALIKLGLLPYGEIRSLDEKSPTLTFNKIGRHVSCVVRTKVVSTL
SPWLSKCMPGDIHTIAVSHGEGRFVADDDIFEELARNGQIATQYVDFDGNPTYDIRFNPN
GSLHAVEGITSPDGRIFGKMGHSERYTKYTLKNVPGEKDQKLFEAGVEYFK
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atggctgtcaggagaatttacgttgaaaagaaacccggttttgatgtaaaagcccgtaaa
ttaatggaagaaataaccgaatacctgaaaattaaaggaattgaaaatgtcagaattata
aacagatatgatgtggaaggtatttcggacgaagactatgaaaaggcgaaaacacttatt
ttttccgagcctccggttgattacgtttatgaagaggaactccccctgagagacaatgaa
agggtttttgcagtggagtatctccccggacagtatgatcagcgtgcagacagttgtgcc
caatgtattcagctcttatccggaaccgagcggcctgaaatacgggttgccacggtaata
gcaattggcggggatatttccgacaaggattttgaaaaaattaaggagtattatataaac
ccgattgaaagcagggaggcggctttaacaaaacccgaaacactccgcgaagagtacgcc
gtacccgacatggttgatgtaataaagggttttacccttatggatgaagaagccctggaa
aaacttattaccgaattgggatttgcaatgtccgttgaagatcttgtcttctgcagggag
tattttaaaaataccgaaaagagagatcccaccgttaccgaattaagagtaattgatacc
tattggtccgatcactgccgtcatacgacatttcttacagaaatagaagaagtttccttt
gacaaaggttctgtatccgaaaaaatttccgaagtttataatctgtatcttgagacgcgt
aaaaaagtgtataaggacagggaaaaacccgtctgccttatggatattgcaacactggcc
atgaaagaactgaaaagagagggatatcttaatgacctggatgaatccgacgaagtcaat
gcatgcagcatcgttgttgatgtggatatagacggcagaaaggaaccttatctggtaatg
ttcaaaaatgagacccacaatcacccgactgaaatcgaaccatttggcggagcggcaacc
tgccttggcggtgccatccgtgatccgctttcgggaagggcctatgtataccaggcgatg
agggtcacgggaagcggtgatccaagaactccggtaactcagacacttcccggaaaactg
ccgcaaagggttataacaaggaaagcggcattgggttacagttcatacggaaatcaggtg
ggacttgcgacaggccaggttaatgagatatatcacgaaggatatgtggccaaacggatg
gaaataggcgcagtaatagcagcagccccaaaatccaatgtggtcaggaaaaagcctgaa
gcgggtgatgtggttattctgctcggcggcaggacgggccgtgacggatgcggcggcgcc
acgggatcatcgaaggcgcataccgaagaatccctgacaaaatgcggggcggaagtgcag
aaaggaaatccgccgacagagagaaaaatacagcgtttattcagaaatcccgaggttaca
aggctaattaaaaaatgcaatgatttcggcgcaggcggtgtttcggttgcaatcggagag
cttgccgacggccttgagatagatttggacgccgttccgaaaaaatatcagggacttgac
ggaactgaacttgcaatttcggaatcccaggaaagaatggcagtggtggttgcgaaggaa
gacgcagagaggtttatagccctttccgcggaagagaatcttgaagcaaccattgttgca
agggttaccgacactaatcgcctcgtaatgaaatggaacggagaaaaaatagtggatatc
agccgtgagtttttaaataccaacggggtaaaacggagaacaaaggtaaccgttaaggaa
cccgggaatatttttgacaattgcgggcagaaggacggccgggatttttccgaaaacttt
aaaaataatctcctgcggcttaatgtatgcagtcagaaaggccttattgaaatgttcgac
agcacggtgggggcgggcacggttctgatgccgcttggaggcaagaatcagttaacgcct
gctgaaggaatggcggctaaaatacccgtagcaaacggagaaacaagaacgggcacacta
atgtccttcggattcgatcccgatatttcatcaaaaagcccgtttcacggggcggtatat
gccattgttgagtcggtggccaaaattgttgctatgggcggggatcacagaaaagtcaga
ctgtcattgcaggaatactttgaaaaggtgggagatgatcccgttaaatggggaaagcct
ttcagcgcgttgatgggtgcgttttatgcccaaatgaagatgaaaattcccgctgtcggc
ggaaaggacagcatgtcggggacttttaaggaccttaatgtgcctccgacgcttgtttct
tttgctgtcagcgtttgcgatgttacaaaggttatatctccggagtttaaaaatccccga
agtacagttgccgttgtaaaaataaaaagggacgagctcgggcttcccgattttgaacat
ttggacaggacttatgaaaggctgcatggtttaataaccgaaaacaggattgtttcagca
tgtacggtgaaatgcgggggtattgccgaagccatttgcaaaatggcttttggaaacgat
atagggtttagctcaaggacaggaataagccctgaaaagtggtttttgcccgactacgga
aacattgtggttgaggtaccgggcgggcacgacattgatgaactgtttgaaggacttgat
tacgaagtcctcggagaaacgactgatgagcccgtgatttccgtcggtaatgaaaagtgg
aatttggatgaactgaaggaattgtggcagtcgccgttggaaagcatattcccgacgaaa
gtaaaggaagaagaaagaaagccaatgaatataatgttcgacggaatgaaaccggtgcac
cacagcggtactttcgcgaaaccgcgggtatttattcctgtttttcccggaacaaactgc
gagtatgaagccgcaatggccttcgaaagggctggagccgttaccgatatttttgtaatg
aaaaaccttactccggcagatataaaagaatcagtaaagatcatgaaagaaaaaatcaaa
aacagtcagataataatgctttcgggaggcttcagtgccggtgacgaacccgacggttcg
ggaaaattcatcgccacggtattccgcaatcctgagcttgccgaagccgtgatggaattt
ttaaaggtgcgcgacgggctgatgctcgggatatgcaatggcttccaggctctgataaaa
cttgggcttctgccttacggcgaaatccggagccttgacgaaaagagtcctacgttgacg
tttaataaaataggaagacacgtctcatgcgttgtaagaacaaaggttgtatccacatta
tcaccatggctgtcaaaatgcatgcccggagacattcatacgatagctgtgtcccacggg
gagggaagatttgtcgccgatgacgatatttttgaagagcttgcaaggaacggccagatt
gcaacccaatatgtggattttgacgggaatcctacatatgatatccggttcaatcccaat
gggtcgctgcatgcagtggaaggcataaccagtcctgacggaaggatattcggaaaaatg
ggccatagtgagcggtatacgaagtatacactgaaaaacgtacccggggaaaaggatcag
aagctattcgaagcaggggtagaatattttaaataa
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