Carlito syrichta (Philippine tarsier): 103252919 Help Entry 103252919         CDS       T07836                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr00230   Purine metabolism csyr01100   Metabolic pathways csyr01522   Endocrine resistance csyr04015   Rap1 signaling pathway csyr04020   Calcium signaling pathway csyr04022   cGMP-PKG signaling pathway csyr04024   cAMP signaling pathway csyr04062   Chemokine signaling pathway csyr04072   Phospholipase D signaling pathway csyr04114   Oocyte meiosis csyr04211   Longevity regulating pathway csyr04213   Longevity regulating pathway - multiple species csyr04261   Adrenergic signaling in cardiomyocytes csyr04270   Vascular smooth muscle contraction csyr04371   Apelin signaling pathway csyr04540   Gap junction csyr04611   Platelet activation csyr04713   Circadian entrainment csyr04714   Thermogenesis csyr04723   Retrograde endocannabinoid signaling csyr04724   Glutamatergic synapse csyr04725   Cholinergic synapse csyr04727   GABAergic synapse csyr04750   Inflammatory mediator regulation of TRP channels csyr04911   Insulin secretion csyr04912   GnRH signaling pathway csyr04913   Ovarian steroidogenesis csyr04914   Progesterone-mediated oocyte maturation csyr04915   Estrogen signaling pathway csyr04916   Melanogenesis csyr04918   Thyroid hormone synthesis csyr04921   Oxytocin signaling pathway csyr04922   Glucagon signaling pathway csyr04923   Regulation of lipolysis in adipocytes csyr04925   Aldosterone synthesis and secretion csyr04926   Relaxin signaling pathway csyr04927   Cortisol synthesis and secretion csyr04928   Parathyroid hormone synthesis, secretion and action csyr04934   Cushing syndrome csyr04935   Growth hormone synthesis, secretion and action csyr04970   Salivary secretion csyr04971   Gastric acid secretion csyr04972   Pancreatic secretion csyr04976   Bile secretion csyr05032   Morphine addiction csyr05163   Human cytomegalovirus infection csyr05166   Human T-cell leukemia virus 1 infection csyr05200   Pathways in cancer csyr05207   Chemical carcinogenesis - receptor activation csyr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:csyr00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103252919 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103252919 (ADCY2)    04371 Apelin signaling pathway     103252919 (ADCY2)    04020 Calcium signaling pathway     103252919 (ADCY2)    04072 Phospholipase D signaling pathway     103252919 (ADCY2)    04024 cAMP signaling pathway     103252919 (ADCY2)    04022 cGMP-PKG signaling pathway     103252919 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103252919 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     103252919 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103252919 (ADCY2)    04062 Chemokine signaling pathway     103252919 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     103252919 (ADCY2)    04922 Glucagon signaling pathway     103252919 (ADCY2)    04923 Regulation of lipolysis in adipocytes     103252919 (ADCY2)    04912 GnRH signaling pathway     103252919 (ADCY2)    04913 Ovarian steroidogenesis     103252919 (ADCY2)    04915 Estrogen signaling pathway     103252919 (ADCY2)    04914 Progesterone-mediated oocyte maturation     103252919 (ADCY2)    04921 Oxytocin signaling pathway     103252919 (ADCY2)    04926 Relaxin signaling pathway     103252919 (ADCY2)    04935 Growth hormone synthesis, secretion and action     103252919 (ADCY2)    04918 Thyroid hormone synthesis     103252919 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     103252919 (ADCY2)    04916 Melanogenesis     103252919 (ADCY2)    04925 Aldosterone synthesis and secretion     103252919 (ADCY2)    04927 Cortisol synthesis and secretion     103252919 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103252919 (ADCY2)    04270 Vascular smooth muscle contraction     103252919 (ADCY2)   09154 Digestive system    04970 Salivary secretion     103252919 (ADCY2)    04971 Gastric acid secretion     103252919 (ADCY2)    04972 Pancreatic secretion     103252919 (ADCY2)    04976 Bile secretion     103252919 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     103252919 (ADCY2)    04727 GABAergic synapse     103252919 (ADCY2)    04725 Cholinergic synapse     103252919 (ADCY2)    04723 Retrograde endocannabinoid signaling     103252919 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103252919 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     103252919 (ADCY2)    04213 Longevity regulating pathway - multiple species     103252919 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     103252919 (ADCY2)    04714 Thermogenesis     103252919 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103252919 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     103252919 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103252919 (ADCY2)    05163 Human cytomegalovirus infection     103252919 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     103252919 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103252919 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103252919 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103252919 (ADCY2) Enzymes [BR:csyr01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103252919 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  103252919 NCBI-ProteinID:  XP_008049698 Ensembl:  ENSTSYG00000000223 UniProt:  A0A1U7SZZ0 LinkDB All DBs Position Unknown AA seq 942 aa AA seqDB search MLPFNMRDAIIASVLTSSSHTIVLSVCLSAMPGTKEHLVWQILANVIIFICGNLAGAYHK HLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKA GQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKEN ECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSG NVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIR DPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAH LHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQ WLKSEDIQRISLLFYNKILEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSILG ISFGAAFLLLAFILFVCFAGQLVQCSKKASPPLMWLLKSSGIITNRPWPRISLTVITTAI ILTMAVFNMFFLSDSEEAISPTANTSNTSFSASNNQAVTLRAQNLFFLPYFIYSCVLGLI SCSVFLRVNYELKMLIMMAALVGYNTILLHTHAHVLGDYSRVLFDRPGIWKDLKTMGSVS LSIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFL ARSLKNEDLYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSK PKFSGVEKIKTIGSTYMAATGLSAIPSQEHTQEPERQYMHIGTMVEFAFALVAKLDAINK HSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLI LQTLGYSCTCRGIINVKGKGDLKTYFVNTEMSRSVSQSNLAS NT seq 2829 nt NT seq  +upstreamnt  +downstreamnt atgctgcccttcaacatgcgagatgccatcattgcaagcgtcctcacctcctcttctcac accatcgtgctgagtgtctgcttgtctgcaatgccaggaaccaaggagcatctggtctgg cagatcctggccaatgtgatcattttcatctgtgggaacctggcgggcgcctaccataag cacctcatggagcttgctctgcagcaaacatatcaggacacgtgtaattgcatcaagtcc cgaatcaagttggaatttgaaaagcgccagcaggagcggcttcttctctccctgctgcca gcccacatagccatggagatgaaagcagagatcatccagaggctgcaaggccccaaagct ggccagatggagaacaccaacaacttccacaatctgtacgtcaagcgacacaccaacgtg agcatcttgtacgctgacattgttggcttcacccggctggcgagcgactgctccccagga gagttagtccacatgctcaacgagctcttcggaaagtttgatcaaattgcaaaggagaat gaatgcatgagaattaaaattttaggagactgctactactgtgtgtctggactgccaatc tctctccctaaccatgccaagaattgcgtgaaaatgggactggatatgtgtgaagccatc aagaaagtaagagatgctactggggttgacatcaacatgcgcgtgggcgtgcattctggg aacgtcttgtgtggtgtgattggtctgcagaagtggcagtacgacgtgtggtcacatgac gttaccttggccaaccacatggaagctggaggggttcctggacgtgttcacatttcttca gtcaccctggagcacttgaatggagcttataaagtggaggagggagatggtgacatcagg gacccatatttaaaacagcacttggtgaaaacatacttcgtaatcaatcccaagggagaa cgcaggagcccccagcatctcttcagacctcgtcacaccctcgatggagccaagatgagg gcctccgtccgcatgacccggtacctggagtcctggggggcggccaagccctttgcacac ctgcatcacagggacagcatgaccacagagaatggcaagatcagcaccacggatgtacca atgggtcagcataattttcaaaatcgcaccttaagaaccaaatcacaaaagaaaagattt gaagaagaattgaatgaaaggatgattcaagcaattgatggaatcaatgcacaaaagcaa tggctcaagtctgaagatattcagagaatctcactgcttttctataacaaaatactagaa aaagaataccgagccaccgcactgccggcattcaagtattacgtgacttgcgcttgtctc atattcttctgcatctttattgtgcagattctcgtattgccaaaaacgtccatcctgggg atttcctttggagctgcatttctcttgcttgcctttatcctgttcgtctgctttgctgga caacttgtgcaatgcagcaaaaaagcttctccccctctcatgtggcttttgaagtcctcg ggcatcatcaccaaccgtccctggccacggatctctctcacggtcatcaccacggccatc atattgaccatggccgtgttcaacatgtttttcctgagtgactcagaggaagcaatctct ccaactgccaatacatcaaatacaagtttttctgcctcaaataatcaggcagtgactctg cgtgcacaaaatttatttttcctcccgtatttcatatacagctgcgttctgggcctgatc tcctgttcggtgttcctgcgggtgaactatgagctgaaaatgctgatcatgatggcggcc ttggtgggctacaacactatcctgctccacacccatgcccacgtcctgggtgactacagc cgggtcttgtttgacagaccaggcatttggaaagacctaaagaccatgggctctgtgtct ctctctattttcttcatcacactgcttgttctgggtagacagaatgaatattactgtagg ttagacttcttatggaagaacaagttcaaaaaagagcgggaggagatagagaccatggaa aacttgaaccgcgtgttgctggagaacgtgcttcccgcccacgtggccgagcacttcctg gccaggagcctgaagaatgaggatttataccaccagtcctatgactgcgtctgtgtcatg tttgcctccattccggatttcaaagaattttacacagaatcagatgtgaacaaggagggc ttggaatgtctccggctcctgaatgagatcatcgccgactttgatgatctgctgtccaag ccaaaattcagtggagttgaaaagatcaagaccattggcagcacatatatggcagcgacg ggtctgagcgccatacccagtcaggagcacacccaggagcctgagcggcagtacatgcac atcggcaccatggtggagtttgccttcgccctggtggccaagctggatgccatcaacaag cactccttcaacgatttcaagttgcgagtgggtattaaccacgggcctgtaatcgctggt gtgattggagctcagaagccgcaatatgatatctggggcaacaccgtcaatgtggccagt aggatggacagcaccggagtcctggacaaaatacaggttactgaggaaaccagcttgatc ctgcagacgctaggatactcgtgcacatgtcgcgggatcatcaacgtgaaggggaagggt gacctgaagacatacttcgtgaacacggaaatgtcaaggtcggtttcgcagagcaacctg gcgtcctga

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