Carlito syrichta (Philippine tarsier): 103263630 Help Entry 103263630         CDS       T07836                                  Symbol KRAS Name (RefSeq) GTPase KRas isoform X2   KO K07827   GTPase KRas Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr01521   EGFR tyrosine kinase inhibitor resistance csyr01522   Endocrine resistance csyr04010   MAPK signaling pathway csyr04012   ErbB signaling pathway csyr04014   Ras signaling pathway csyr04015   Rap1 signaling pathway csyr04062   Chemokine signaling pathway csyr04068   FoxO signaling pathway csyr04071   Sphingolipid signaling pathway csyr04072   Phospholipase D signaling pathway csyr04137   Mitophagy - animal csyr04140   Autophagy - animal csyr04150   mTOR signaling pathway csyr04151   PI3K-Akt signaling pathway csyr04210   Apoptosis csyr04211   Longevity regulating pathway csyr04213   Longevity regulating pathway - multiple species csyr04218   Cellular senescence csyr04360   Axon guidance csyr04370   VEGF signaling pathway csyr04371   Apelin signaling pathway csyr04540   Gap junction csyr04550   Signaling pathways regulating pluripotency of stem cells csyr04625   C-type lectin receptor signaling pathway csyr04650   Natural killer cell mediated cytotoxicity csyr04660   T cell receptor signaling pathway csyr04662   B cell receptor signaling pathway csyr04664   Fc epsilon RI signaling pathway csyr04714   Thermogenesis csyr04720   Long-term potentiation csyr04722   Neurotrophin signaling pathway csyr04725   Cholinergic synapse csyr04726   Serotonergic synapse csyr04730   Long-term depression csyr04810   Regulation of actin cytoskeleton csyr04910   Insulin signaling pathway csyr04912   GnRH signaling pathway csyr04914   Progesterone-mediated oocyte maturation csyr04915   Estrogen signaling pathway csyr04916   Melanogenesis csyr04917   Prolactin signaling pathway csyr04919   Thyroid hormone signaling pathway csyr04921   Oxytocin signaling pathway csyr04926   Relaxin signaling pathway csyr04929   GnRH secretion csyr04933   AGE-RAGE signaling pathway in diabetic complications csyr04935   Growth hormone synthesis, secretion and action csyr04960   Aldosterone-regulated sodium reabsorption csyr05010   Alzheimer disease csyr05022   Pathways of neurodegeneration - multiple diseases csyr05034   Alcoholism csyr05160   Hepatitis C csyr05161   Hepatitis B csyr05163   Human cytomegalovirus infection csyr05165   Human papillomavirus infection csyr05166   Human T-cell leukemia virus 1 infection csyr05167   Kaposi sarcoma-associated herpesvirus infection csyr05170   Human immunodeficiency virus 1 infection csyr05200   Pathways in cancer csyr05203   Viral carcinogenesis csyr05205   Proteoglycans in cancer csyr05206   MicroRNAs in cancer csyr05207   Chemical carcinogenesis - receptor activation csyr05208   Chemical carcinogenesis - reactive oxygen species csyr05210   Colorectal cancer csyr05211   Renal cell carcinoma csyr05212   Pancreatic cancer csyr05213   Endometrial cancer csyr05214   Glioma csyr05215   Prostate cancer csyr05216   Thyroid cancer csyr05218   Melanoma csyr05219   Bladder cancer csyr05220   Chronic myeloid leukemia csyr05221   Acute myeloid leukemia csyr05223   Non-small cell lung cancer csyr05224   Breast cancer csyr05225   Hepatocellular carcinoma csyr05226   Gastric cancer csyr05230   Central carbon metabolism in cancer csyr05231   Choline metabolism in cancer csyr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer csyr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:csyr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103263630 (KRAS)    04012 ErbB signaling pathway     103263630 (KRAS)    04014 Ras signaling pathway     103263630 (KRAS)    04015 Rap1 signaling pathway     103263630 (KRAS)    04370 VEGF signaling pathway     103263630 (KRAS)    04371 Apelin signaling pathway     103263630 (KRAS)    04068 FoxO signaling pathway     103263630 (KRAS)    04072 Phospholipase D signaling pathway     103263630 (KRAS)    04071 Sphingolipid signaling pathway     103263630 (KRAS)    04151 PI3K-Akt signaling pathway     103263630 (KRAS)    04150 mTOR signaling pathway     103263630 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103263630 (KRAS)    04137 Mitophagy - animal     103263630 (KRAS)   09143 Cell growth and death    04210 Apoptosis     103263630 (KRAS)    04218 Cellular senescence     103263630 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     103263630 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     103263630 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103263630 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     103263630 (KRAS)    04650 Natural killer cell mediated cytotoxicity     103263630 (KRAS)    04660 T cell receptor signaling pathway     103263630 (KRAS)    04662 B cell receptor signaling pathway     103263630 (KRAS)    04664 Fc epsilon RI signaling pathway     103263630 (KRAS)    04062 Chemokine signaling pathway     103263630 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     103263630 (KRAS)    04929 GnRH secretion     103263630 (KRAS)    04912 GnRH signaling pathway     103263630 (KRAS)    04915 Estrogen signaling pathway     103263630 (KRAS)    04914 Progesterone-mediated oocyte maturation     103263630 (KRAS)    04917 Prolactin signaling pathway     103263630 (KRAS)    04921 Oxytocin signaling pathway     103263630 (KRAS)    04926 Relaxin signaling pathway     103263630 (KRAS)    04935 Growth hormone synthesis, secretion and action     103263630 (KRAS)    04919 Thyroid hormone signaling pathway     103263630 (KRAS)    04916 Melanogenesis     103263630 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103263630 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     103263630 (KRAS)    04726 Serotonergic synapse     103263630 (KRAS)    04720 Long-term potentiation     103263630 (KRAS)    04730 Long-term depression     103263630 (KRAS)    04722 Neurotrophin signaling pathway     103263630 (KRAS)   09158 Development and regeneration    04360 Axon guidance     103263630 (KRAS)   09149 Aging    04211 Longevity regulating pathway     103263630 (KRAS)    04213 Longevity regulating pathway - multiple species     103263630 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     103263630 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103263630 (KRAS)    05206 MicroRNAs in cancer     103263630 (KRAS)    05205 Proteoglycans in cancer     103263630 (KRAS)    05207 Chemical carcinogenesis - receptor activation     103263630 (KRAS)    05208 Chemical carcinogenesis - reactive oxygen species     103263630 (KRAS)    05203 Viral carcinogenesis     103263630 (KRAS)    05230 Central carbon metabolism in cancer     103263630 (KRAS)    05231 Choline metabolism in cancer     103263630 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103263630 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     103263630 (KRAS)    05212 Pancreatic cancer     103263630 (KRAS)    05225 Hepatocellular carcinoma     103263630 (KRAS)    05226 Gastric cancer     103263630 (KRAS)    05214 Glioma     103263630 (KRAS)    05216 Thyroid cancer     103263630 (KRAS)    05221 Acute myeloid leukemia     103263630 (KRAS)    05220 Chronic myeloid leukemia     103263630 (KRAS)    05218 Melanoma     103263630 (KRAS)    05211 Renal cell carcinoma     103263630 (KRAS)    05219 Bladder cancer     103263630 (KRAS)    05215 Prostate cancer     103263630 (KRAS)    05213 Endometrial cancer     103263630 (KRAS)    05224 Breast cancer     103263630 (KRAS)    05223 Non-small cell lung cancer     103263630 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103263630 (KRAS)    05170 Human immunodeficiency virus 1 infection     103263630 (KRAS)    05161 Hepatitis B     103263630 (KRAS)    05160 Hepatitis C     103263630 (KRAS)    05163 Human cytomegalovirus infection     103263630 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     103263630 (KRAS)    05165 Human papillomavirus infection     103263630 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     103263630 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     103263630 (KRAS)   09165 Substance dependence    05034 Alcoholism     103263630 (KRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103263630 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103263630 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103263630 (KRAS)    01522 Endocrine resistance     103263630 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:csyr04131]     103263630 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:csyr04031]     103263630 (KRAS) Membrane trafficking [BR:csyr04131]  Endocytosis   Macropinocytosis    Ras GTPases     103263630 (KRAS) GTP-binding proteins [BR:csyr04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     103263630 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase MeaB FeoB_N ATP_bind_1 Septin G1_gp67_C NPR1_interact Motif Other DBs NCBI-GeneID:  103263630 NCBI-ProteinID:  XP_008059486 Ensembl:  ENSTSYG00000032750 UniProt:  A0A1U7U0Q4 LinkDB All DBs Position Unknown AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaatacagaatcactttgtggatgaatatgatccaacaatagaggattcctac aggaagcaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgattta ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

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