Carlito syrichta (Philippine tarsier): 103274296
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Entry
103274296 CDS
T07836
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr00562
Inositol phosphate metabolism
csyr01100
Metabolic pathways
csyr01521
EGFR tyrosine kinase inhibitor resistance
csyr04068
FoxO signaling pathway
csyr04070
Phosphatidylinositol signaling system
csyr04071
Sphingolipid signaling pathway
csyr04115
p53 signaling pathway
csyr04140
Autophagy - animal
csyr04150
mTOR signaling pathway
csyr04151
PI3K-Akt signaling pathway
csyr04218
Cellular senescence
csyr04510
Focal adhesion
csyr04931
Insulin resistance
csyr05165
Human papillomavirus infection
csyr05166
Human T-cell leukemia virus 1 infection
csyr05200
Pathways in cancer
csyr05206
MicroRNAs in cancer
csyr05208
Chemical carcinogenesis - reactive oxygen species
csyr05213
Endometrial cancer
csyr05214
Glioma
csyr05215
Prostate cancer
csyr05218
Melanoma
csyr05222
Small cell lung cancer
csyr05224
Breast cancer
csyr05225
Hepatocellular carcinoma
csyr05230
Central carbon metabolism in cancer
csyr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
csyr05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
103274296 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
103274296 (PTEN)
04070 Phosphatidylinositol signaling system
103274296 (PTEN)
04071 Sphingolipid signaling pathway
103274296 (PTEN)
04151 PI3K-Akt signaling pathway
103274296 (PTEN)
04150 mTOR signaling pathway
103274296 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103274296 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
103274296 (PTEN)
04218 Cellular senescence
103274296 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103274296 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103274296 (PTEN)
05206 MicroRNAs in cancer
103274296 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
103274296 (PTEN)
05230 Central carbon metabolism in cancer
103274296 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103274296 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103274296 (PTEN)
05214 Glioma
103274296 (PTEN)
05218 Melanoma
103274296 (PTEN)
05215 Prostate cancer
103274296 (PTEN)
05213 Endometrial cancer
103274296 (PTEN)
05224 Breast cancer
103274296 (PTEN)
05222 Small cell lung cancer
103274296 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103274296 (PTEN)
05165 Human papillomavirus infection
103274296 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103274296 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
103274296 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103274296 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
csyr01009
]
103274296 (PTEN)
Enzymes [BR:
csyr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
103274296 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
103274296 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
103274296 (PTEN)
Protein phosphatases and associated proteins [BR:
csyr01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
103274296 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
103274296
NCBI-ProteinID:
XP_008069943
Ensembl:
ENSTSYG00000009249
UniProt:
A0A1U7UMJ6
LinkDB
All DBs
Position
Unknown
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggaggtatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctatgtgctgaaagacattatgacaccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataacccaccacagctagaactt
atcaaacctttttgtgaagatcttgaccaatggctaagtgaagatgacaatcacgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggtaaatttttaaaggcacaagaggccctagatttctacggggaagtaaggacc
agagataaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattacctgtgtgtggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggataaaatgtttcacttttgggtaaatacgttcttcata
ccaggaccagaagaaacttcagagaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaggccaaccgatacttctctccaaat
tttaaggtgaagctgtattttacaaaaacagtagaggagccatcaaatccagaggcaagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaacgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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