Crotalus tigris (Tiger rattlesnake): 120313022
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Entry
120313022 CDS
T08476
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ctig
Crotalus tigris (Tiger rattlesnake)
Brite
KEGG Orthology (KO) [BR:
ctig00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ctig01001
]
120313022 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ctig04131
]
120313022 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ctig04147
]
120313022 (LRRK2)
Enzymes [BR:
ctig01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120313022 (LRRK2)
Protein kinases [BR:
ctig01001
]
Serine/threonine kinases: TKL group
LRRK family
120313022 (LRRK2)
Membrane trafficking [BR:
ctig04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
120313022 (LRRK2)
Exosome [BR:
ctig04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
120313022 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_1
Arf
Ank_2
NACHT
AAA_22
LRR_9
ABC_tran
AAA_16
nSTAND3
G-alpha
Gtr1_RagA
Kdo
TrwB_AAD_bind
MMR_HSR1
AAA_29
cobW
SRPRB
MobB
Motif
Other DBs
NCBI-GeneID:
120313022
NCBI-ProteinID:
XP_039210432
LinkDB
All DBs
Position
Unknown
AA seq
2527 aa
AA seq
DB search
MASAAPVSPAEADEERREAALRKLLVRLRSLQAGKQLESLVQTLQDLLAFAALPGGARLF
ADGSAYVPLLLVLVSYLRVGRVQQVGWTLLCKLIKICPETLHRLAGPQGVGKDWEVLGVH
QQILKMLKTHSADVDLSTVGLKTLNLLLSSDEITLLLLEEGTDIFLLVFDAMDSFPDNEK
IQRYGCKALHMLLEKVPEEQLIEFVEANDHMIILRVFKQFPEKENIICLALQSLYLLAGP
LSNAEVLMSGNVRCYNIVVEVMKAFPACEPIQEVSCCLLHKLTLENFFNILVLNCVHEVI
LKAVETYPGNEKLQAAGISCLALLTETIFLNRDLEDKKEEEEDEENKFCWLEACYKALKC
HRRNRGVQEAACWALNNLLMYQPTLNEKIGDEEGKYPAHREMMLAMLMYSSSKEVFQAAA
NALATLVKQNANARRILLAKGIHINVLEIMKKYSNSPEIAEGACRLLNHAFEGSFLQLDI
MLAAASGSVQTMKKHKSLPSVQLEALKVILRCMAPGILNNQQHVGSENPNLQTELTFMKN
NFFLEDGHSLVLGALNTFIGNPGIQRYGLQILSCVKESSTLLQLLSNLGMTDTVLHTLQM
YPDDQEIQHLGLNLLGSLVSGKRLCTVTFYVLVSPLVSTLRRFKDVVEIQTQGYQIITTI
LDSSPWFANLLIQESFDTCLFYQLSTCFNEQRDQQLQSLCCKCFAKITQHEDLKNVMLEK
ACAEGNSVMAECLLLLGADVNQSSKEKSLIYEVCEKGSNPKLVELLLNSGAREPDVRSAL
TVSIKKGDSGIISLLLKKLCLDVANSSICLGGFSLGQIEPSWLVPLFPSRPLSFRKQTSS
ALAVMVLRYQRTSSYKDESRSDINSQTDEMQKFDEWTFLPDPLVDNVFSLSDDVESEGSE
SSFMVRQKSYSVAAADLQKPLQAYSPPLQRHSRSVGLGSPYEPLTNQRRKNVFSEESHKG
TSVFQSNLKSSDSFSSLVSDREYIKSLDLSSNELENVDPISQSLCLITHFEHLDKLELHH
NQLSCIPKQLCETLKCLTYLDLHSNRLKSFPQCLLEMPQIAHLDVSRNEIGPTLCFNPKV
TCPTLKLLNLSYNQLSHIPRDLGDVLIKLEHLILEGNRLSALVGRLGLKELKSLNISKND
ISYLDTELLQECLKLEILNAAVNRIDAIYTLPSNITTLKLAKNAFITVPPAILLLPHLRS
VDLSSNSIGILPDPASWKSSNLRELIFNRNQISILDLNDKAACWAGLEKLHLSNNKLREI
PPEIGFLENLTSFDVSYNPAIRCFPDEMGKLSNIWDLPLEGLHLNLDFKHVGGKARDIIR
FLQLRLKKAVPYHRMKLMIVGNAGSGKTTLLRQLMKWKRPDLAPQTPTIGIDVHDWKIPR
RGKIKKDTILNVWDFAGQEEFYSAHLHFMTQRALYLVVYDLSKGESEVDAMKPWLFNIKT
RASFSPVILIGTHLDISAEKQRRVCIDKITKELMNQKGFPKIHDYHFVKATEESESMTKL
RQIIIKECLEFKIRDQPVIGQLIPDSYLELEKSILEIRKTLPAEFPVICQSQLYELVQEN
QLQLDENELSHAVHFLNESGVLLHFQDPALQLRNLYFVDPKWLCKIIGQILTVKVDGFTK
YPKGIIKRSDVEKSLLKNSKFPEICKGQYFKLLEKFQIALPLGEDQLLIPSSLSDQRPVI
ELPHCENSELIIRLYEMPYFPMGFWSRLINRLLEVSSYMLSGRERALRPNKMYWRQGIYL
SWSPEAYTLVESAVLENNLNSFLKITVPSCRKGCIILGQVVDHIDSLMEEWFPGLLEVDI
CGEGETLLKKWALYSFEDGEEHRKILLDDLLKKAEEGDLLINPDQPRSTVPIAQIAPDLI
LADLPRNIMLNNDELEFHQAPENLLGDGGFGSVYRAVYVGEEVAVKIFNKHTSLRLLRQE
LAVLCHLHHPSLVFLMAAAVRPRMLVMELAPKGSLDRLLQQENACLTRTLQHRIALHVAD
GLRYLHSSMIIYRDLKPHNVLLFTLYPNSAVIAKIADYGISQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTAGGRILEGIKFPHEFDELAIHGKLPDPVKEYG
CAPWPRFEDLIKKCLKENPQERPTSDQVYETLNSAELVCFMRHISVPSPLASECMVATNQ
SNKKTGIWIGSGGRGEAQLSFVDVNTDERACENVEDSRILSLALVTVSAAKENWVIAGTQ
SGSLWSFHTQDGERRHQFHTMSDSVTCLYCSPLSKHNKYRNIFLVGTANGQLAIFEDRAV
KGKCAGPLRTFLIGSSSTPLMCLSESSYSSDKSTLWGGCGTKILSLSSDLSTHKLIETNT
SQLLCHKNYCDANIISIAVDKFIYLAKKESYLVEIWDKKTEQLCELIDCVHLLKAEVPKL
NRESKQKLAYPGRVKSICLQKNTALWIGTGGGHIILLDLSTRLPIRIIHDFCRSVRMMRT
TQLGTLKNVVLVLGYNHAKDSEDEHIKGMQSSVSIWDVNLSHEVQNLKKHIAMRQELAEK
MKSFSLD
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagcgccgcgccggtctcgccggccgaggcggacgaggagcggcgggaagcggcg
ctgcggaagctgctggtccggctgcggagcctgcaggcggggaagcagctggagagcctg
gtgcagacgctgcaggacctgctggccttcgccgccctgcccggcggagccaggctcttc
gccgacgggagcgcctacgtgcctctgctgctggtgctggtctcctacctgagagtgggg
cgcgtgcaacaggtgggttggacacttctctgcaaacttattaaaatatgcccagaaact
ctgcatcgtttagcaggtcctcaaggagtggggaaggactgggaagttctcggtgttcat
cagcaaattcttaagatgcttaaaacccacagtgctgatgtggatctttcaactgtgggc
ttgaaaacattaaacctgcttctttcttcagatgaaatcacacttcttctcttagaagaa
gggaccgacatatttttattggtatttgatgccatggattcctttcccgataatgaaaag
atccagagatatggatgtaaagctttgcacatgcttttagaaaaagttcctgaggagcag
ctgattgaatttgtggaagcgaacgatcacatgattatactaagagtgtttaaacaattc
ccagagaaggagaatatcatctgtttggcacttcagtccttgtatctgttggctggacca
cttagcaatgcggaagttctcatgtctggaaatgtgcggtgttacaatatcgtagtggag
gttatgaaagcgttccctgcatgtgagccaattcaggaagttagctgctgtctgctgcac
aaacttactctcgaaaactttttcaatatcctcgtattgaattgtgtacacgaagtgatt
ctgaaggctgtagaaacgtaccctggaaatgagaagctacaggcagctggcattagttgt
ctggctctcctcacggaaaccatctttttaaacagagatttggaagacaaaaaggaagaa
gaggaagatgaagaaaataaattctgttggctggaggcctgctataaagcattaaaatgt
cacagaagaaatagaggcgtacaggaagctgcttgctgggcattgaacaatctgcttatg
tatcagcctactcttaatgagaagattggggacgaagaaggaaagtacccagcgcacaga
gaaatgatgctggctatgttgatgtattcttcttccaaagaagtgttccaggcagctgcc
aatgccttagctactctcgtgaagcaaaacgcaaatgctagaagaattctcttggcgaaa
ggtatacacatcaacgtgctggagatcatgaagaaatattccaattctcccgaaattgca
gaaggtgcctgccgattgctaaaccatgctttcgaaggaagtttcttacaattggatatc
atgctcgccgctgcatctggaagtgtgcagaccatgaagaaacataaatctttgccatcc
gtccagttggaagcacttaaagtgattttacgttgcatggctccaggtatactaaacaat
cagcagcacgttggttcggaaaaccctaacctgcaaacagagttaacatttatgaaaaat
aactttttcttagaagatggccattctcttgtccttggtgctctgaacacgttcattgga
aatccaggcatccagagatatggactccaaatactttcctgtgtcaaagaatcctccact
ctattacaattgttatcaaatctaggaatgacagatactgtgctccacacgctacagatg
tacccggatgatcaagaaatacaacacttaggtttaaatcttctgggatccctggtatca
ggaaagagattgtgtacagttactttctatgtcctggtatcacccttggtttcgacatta
cgacgctttaaggatgtggttgaaattcagactcagggatatcaaattattacaaccata
ctcgactcgtccccttggtttgcaaacctgctcatccaggaatcgtttgatacctgtctc
ttctatcaactctccacatgctttaatgagcaaagagatcagcagcttcaaagtctttgt
tgtaaatgctttgcgaaaataactcaacacgaggacttgaaaaacgtgatgttggagaag
gcctgtgccgaaggcaacagcgttatggccgaatgtttgctgctgctgggtgccgatgtg
aaccaaagctcgaaggagaagtctttaatttacgaagtatgtgagaaaggaagcaaccca
aaattggttgaactactgctcaacagcggtgcccgggaacccgatgttcgaagcgctctg
acagtcagcatcaagaaaggagacagtggaatcattagcctgcttcttaaaaaactttgc
ctggatgtggccaacagcagcatatgtctgggaggattcagccttgggcaaattgagcct
tcttggctggtccccttgtttccaagcagacctctgtccttccggaagcaaaccagttcc
gcgttggccgtaatggtccttcgatatcagaggacgagtagttacaaagatgagtcaaga
tctgacataaacagccagactgatgaaatgcagaaatttgatgaatggacgttcttacct
gatcctttagttgacaatgtcttctctttgagtgacgacgtcgagagcgaaggcagtgaa
agctcatttatggtaaggcagaaatcttactccgtggcggccgcagacctccagaaacct
cttcaggcctactctcctcccctccaaagacattccagatctgtggggcttggatcacct
tacgaaccattaacgaaccaaagaagaaaaaatgtgttttctgaagaatcccacaaaggc
acgtctgtcttccaatcaaacctgaagagctcggacagtttttcttccctggtctctgac
agagaatatattaaatccctcgacctgtcttcaaatgagctggagaacgtagatcccatc
agtcaaagtctttgcttaattacccacttcgaacatctcgacaaattggaactgcatcac
aatcagctttcctgcattccaaaacaactttgtgagaccttgaaatgtttgacttatctc
gacctgcacagcaaccgcttgaagtctttcccacagtgtctcttggaaatgcctcagatc
gctcacctcgacgtttcgcgcaatgaaattgggcctaccttatgtttcaatccaaaagtc
acctgtccgaccttaaaattactcaatttgtcatacaaccaactgtcacacattcctaga
gatcttggcgatgttctgatcaagctggagcatctcatattggaagggaacagactttca
gcgttagttgggcgcctaggtttaaaagaactgaaaagtttaaacattagcaagaatgat
atatcgtacctggatacagaacttctgcaggagtgtttgaaattggaaatactcaatgca
gctgtaaatagaattgatgccatatacaccttgccttctaacataaccacattgaaacta
gctaagaatgcttttatcactgttccaccggcaattcttcttttaccacatttgcgatcg
gtggatttaagcagcaatagcattggaattttacctgatcctgcatcttggaaatcttca
aatttaagagaattgatatttaaccgcaatcaaataagcattctagacttgaacgacaaa
gctgcttgctgggctgggcttgaaaaactacacctgtctaacaacaaattaagagagatt
cctccagaaatcgggttccttgaaaacttgacatcttttgacgttagttacaatccagca
atacggtgttttccagatgaaatggggaaattgtcgaacatctgggaccttcctttggaa
gggttacaccttaacttagatttcaaacacgtgggaggcaaagcaagggatattatcaga
ttccttcaactgcgcttgaagaaggccgttccctaccaccgaatgaagctcatgattgtt
ggaaacgccggcagcggtaaaacaaccttgttacgacaactgatgaaatggaagaggcca
gatttggcccctcagactccaaccatcggcattgatgtgcatgactggaagattccccga
aggggcaaaatcaagaaagacacaattttaaacgtctgggattttgcaggtcaagaagaa
ttctatagcgctcatctccattttatgactcagcgagctctctacctcgtggtttatgac
cttagcaaaggggaatcagaagtggatgccatgaaaccgtggctgtttaatatcaagacc
cgagcgtcattctcccctgtgattctcatcgggactcatttagacatctctgccgagaag
cagcgtagagtttgcatcgataaaatcaccaaggagttgatgaatcagaagggatttccc
aaaatccacgactatcactttgtgaaagccaccgaagagtctgaatcgatgactaagctt
cgacaaatcatcatcaaagaatgcctggagtttaaaatcagagatcagccggtgattggc
cagttaattccagacagctacttggaactcgagaagagtattctggaaatacgcaaaacg
ttaccggctgagttccctgtgatctgccagagtcagctttacgaattggtgcaagaaaac
cagctacaattggacgaaaatgagctttcgcacgcggtgcattttctgaacgaatcgggt
gtcctcctccactttcaggatcccgcccttcagctccgaaatttgtattttgtcgatccc
aagtggctgtgtaaaatcatcggccagatcttgaccgtgaaggttgatggctttacgaag
taccccaaagggatcataaagcgttctgatgtggaaaaatccctgctaaagaatagtaaa
tttcctgagatctgcaagggccaatacttcaagctgctagagaagtttcagattgctttg
ccactcggagaagatcaactgcttattccgagcagcttgtcagatcaacggcctgtgata
gaattacctcactgtgaaaactctgagcttattatcagattgtatgagatgccctatttt
cctatgggattctggtcccggctaattaatcgactgcttgaagtgtcttcatacatgctt
tcgggaagagaacgagctcttcgtcctaacaagatgtattggaggcaaggcatatatctg
agttggtctccggaagcttacaccttggtggaatctgcagttctggaaaacaatctcaac
agctttttaaaaatcacggtcccttcttgcagaaaaggttgcattattttggggcaagtt
gtagatcacatcgattctctcatggaggagtggttcccgggtctattagaagtagatatt
tgtggcgaaggagaaacactgttgaaaaaatgggctttgtacagttttgaagatggagaa
gaacatcggaaaatattgcttgacgacctacttaaaaaggcagaggaaggtgacctctta
ataaatccagatcaacccaggtctactgttccaattgctcaaattgctcctgatttgatt
ttggcggatttacccagaaacatcatgttgaacaacgatgagctggaattccaccaagct
ccagagaaccttcttggcgacggcggatttggatctgtgtaccgcgcagtttacgtcggc
gaagaagtagctgtaaagatttttaataagcatacatcccttaggctcctgagacaggaa
cttgctgtgctttgtcatctccatcatcctagcttggtattcttgatggctgcagctgtg
cgaccccggatgcttgtcatggaattagccccaaaggggtctttagatcggttactgcag
caagaaaatgcatgtctaaccagaaccttgcagcacaggatagctctgcatgttgcagat
ggcctgaggtacctacattcttcaatgatcatttatcgtgacttaaagccccacaacgtc
ttgctcttcacgctttatcccaattcagcagtcattgccaagattgccgattatggcatt
tcccaatattgttgccggatgggaataaaaacctccgaaggcacaccaggatttagagca
ccagaagtcgcaagaggaaacgttatttacaatcagcaagctgatgtttattcgtttggc
ttgctgctatatgacattttaacagctggtgggagaatattagagggcataaaatttcct
catgaatttgatgaattagctatccatgggaaactgccagatcccgtcaaagagtacggc
tgtgccccttggccaagatttgaagatttaattaagaaatgtttgaaagaaaatcctcaa
gaaagacctacgtctgaccaggtttatgaaacgttgaactctgccgagctcgtttgtttc
atgagacacatttcggtgccctctcctttggcgtcggaatgcatggtggccacaaaccaa
agtaacaagaagaccgggatctggatcgggagtggcggcaggggagaggcccagctctcg
tttgtcgacgtaaacacagacgaacgcgcctgcgaaaacgttgaagacagtagaatctta
agtttggccttggttaccgtttccgcagcgaaggagaactgggtgattgcaggaacccag
tcaggatccctctggtcctttcacacccaagatggagaacgcaggcatcagtttcacacc
atgtcagattcggtcacctgcctttactgcagtcccttgtcaaagcataacaagtaccgg
aatatctttttggtgggcacagccaatggacagctggccatttttgaggacagagcagtc
aagggcaaatgtgctggacccttaaggacttttctcattggaagtagcagcacgccactg
atgtgtttaagtgaatcaagttattcatccgacaaaagtacactctggggtggctgtgga
acaaagatactatcgttgtccagcgatttgtctacccacaaactcattgagaccaacacg
agtcagctattatgtcacaagaactactgtgatgccaatattatttctatagcagtggac
aaatttatctacttggccaagaaggaaagctatcttgttgagatttgggacaaaaaaacg
gagcagctttgtgaactaattgactgcgtgcatctactaaaagcggaggtcccaaagctg
aacagggaatcgaaacaaaaactggcgtatcccggaagagtgaagagtatttgtcttcag
aaaaatacggccttgtggatcggtacagggggaggacacatcatactactggacctgtcc
acgcgcctccccattcggataattcacgatttctgtcgttcagtgagaatgatgaggacc
acacagctaggcaccctcaagaatgttgttctggtcttgggttataaccacgcgaaggat
agtgaagacgaacacattaaaggaatgcaatcttctgtgtcaatctgggacgttaacctg
tcacacgaagtgcaaaacctgaaaaaacatatcgcaatgaggcaagaactagctgagaag
atgaagagtttttcgttggattag
DBGET
integrated database retrieval system
