Chloracidobacterium thermophilum: Cabther_A0524
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Entry
Cabther_A0524 CDS
T01629
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ctm
Chloracidobacterium thermophilum
Pathway
ctm00790
Folate biosynthesis
ctm01100
Metabolic pathways
ctm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ctm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Cabther_A0524
Enzymes [BR:
ctm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Cabther_A0524
6.3.2.17 tetrahydrofolate synthase
Cabther_A0524
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AEP11282
UniProt:
G2LE62
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Position
1:611375..612706
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AA seq
443 aa
AA seq
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MDFEAATRYLQALGNEVTTMKLGLEAMRVLLAELGQPERKFCAVHVAGTNGKGSTCAFLA
SIFQQAGLRTGLYTSPHLISPVERIKLNGQSIPEAAFAEVMTQVHDAVESLLEQGRLAAR
PTFFEHLTAAAFTYLAARQAEVVVAEVGLGGRLDATNVLHPAAAVITNIGEDHREWLGPT
LSHIAREKAGIIKPGVPVYLADTQPEEARRVLAHSALAQQVEPQWVAPFETVHLDATGCP
SVRFDQRFPSLEGGVCRLSLRGRHQTQNAALAAVVAQAELRRRGVAESDIGRAIVAGLET
THWPGRLQWLETTPPVLLDGAHNPQGAQALAHFLESIGGRRPRTAIFATMRDKPAADLLS
ALASGVDRLILTGVKNQPRTMPRESLEVIALGYWLPSGIIQAPDVAMALARARELTPPEG
LILVCGSIYLIGEALQALQVPVL
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
atggactttgaggctgctacccgatacctgcaggctttgggcaatgaagtcaccacgatg
aagcttggccttgaagccatgcgcgtgcttttggccgagctggggcagcctgagcggaaa
ttctgcgccgttcacgttgccggcacgaacggcaaaggttcgacctgcgcgtttctggcc
agcatcttccagcaggcgggtttgcgtaccgggctgtacacctcgccccacctgataagt
cccgtggagcgcatcaaactcaatgggcagagtatcccggaagccgcttttgcagaggtc
atgacgcaggttcatgacgcggttgagtcattgttggaacaggggcgtctggctgcgcgt
ccgacgttttttgagcatctcacagccgcggcctttacctacctggccgcccggcaggcc
gaggtcgtcgtggccgaagtcggcctgggcggccggctggatgccaccaacgtcctgcac
ccagcggcggcagtcatcaccaacatcggcgaagaccaccgggaatggctggggcccacg
ctgtcccacatcgcccgtgaaaaggccgggatcatcaagcccggcgtgccggtgtacctg
gcggacacccagccagaggaagcgcgccgggtgttggcgcactctgccctggcgcagcag
gttgaaccgcagtgggtggctcccttcgagaccgtacatctggatgccacgggctgccct
tctgtccgctttgaccagcgctttcccagcctggaaggcggagtgtgccggttgtcgctg
cgcggcaggcatcagacgcaaaacgcggctctggcggccgtggttgcccaggctgaactg
cgccgccggggtgtagccgaaagcgacatcggccgggcgattgtggccggactggaaacc
acccactggcccggacgtttacagtggctggagacaactccgccggtactgcttgacggc
gcgcacaacccacagggagcgcaggcgctggcgcactttctggaaagcattggcgggcgg
cgtccccgaaccgccatctttgccaccatgcgcgacaaaccggccgccgatctgctgtcg
gcactggcgtcgggtgtggatcgtctgattctgacgggggtcaaaaaccagccccggacg
atgccgcgtgagagtctcgaagtcattgccctgggctactggctgccgtcgggtatcatc
caggcgccggatgtcgccatggcgctggcccgggcccgcgaactgacgccacctgaaggg
ctgattctcgtctgcggctccatttacctcatcggcgaggcactccaggcgctgcaagtg
ccggttttgtga
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