Cupriavidus sp. KK10: KB879_24960
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Entry
KB879_24960 CDS
T08941
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
cuk
Cupriavidus sp. KK10
Pathway
cuk00790
Folate biosynthesis
cuk01100
Metabolic pathways
cuk01240
Biosynthesis of cofactors
Module
cuk_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
cuk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KB879_24960 (folC)
Enzymes [BR:
cuk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
KB879_24960 (folC)
6.3.2.17 tetrahydrofolate synthase
KB879_24960 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QUN27300
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Position
complement(5355244..5356554)
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AA seq
436 aa
AA seq
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MPVFHTLPEWLAHLETAHPVGIDMGLARITRVKEALGLRIDAVVFTVGGTNGKGSTCAML
ERILLEAGYKVGCHTSPHLISFNERARINGEIATDAQLLPHFEAVERARNSFADPVSLTY
FEFTTLAIIHAFAAAGLDAIILEVGLGGRLDAVNVIDTDCAIVTSVDIDHTQYLGHTREE
IGFEKAGIFRPGVPAICGDPMPPKSLVAHAEAVGAELWLVGRDYHFHAAKGQERQQWDWS
GGGRKLNGLGYPALRGANQLLNAAAALAALQAMRPRLPVSAQEVRNGLAFVELPGRFQVL
PGRPAVILDVAHNPHAAATLGQNLENMGFFRYTYAVFGAMQDKDIAGVLQHVADKVDHWC
LCDLPTERAASAADLLAKLEAGGFRPGPDATAACFSSPEAAFRDAIERATENDRILVFGS
FYTVAGVMAYRATQAN
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgcctgtcttccatacgctccccgaatggcttgcccatctcgaaaccgcccatcccgtg
ggcatcgacatgggcctggcgcgcatcacgcgcgtgaaggaggccctcgggctgcgcatc
gacgctgtggtgttcacggtgggcggcaccaacggcaagggctctacctgcgcgatgcta
gagcgcatcctgctggaggccggctacaaggtgggctgccatacctcgccgcacctgatc
tcgttcaacgagcgcgcccgcatcaatggcgagatcgccaccgatgcgcagctgctgccg
catttcgaggcggtcgagcgcgcacgcaacagctttgccgacccggtcagcctgacgtac
ttcgagttcaccacgctggcgatcatccatgccttcgccgcggccgggctggacgcgatc
atcctggaagtaggcctgggcgggcggctggacgcggtcaacgtaatcgataccgactgc
gccatcgtcaccagcgtcgatatcgaccatacccagtacctgggccatacgcgcgaggaa
atcggcttcgagaaggccggcatcttccgcccgggcgtgcccgcgatctgtggcgacccg
atgccgcccaagtcgctggtggcgcacgccgaagcggtcggcgccgagttgtggctggtg
gggcgcgattaccatttccacgccgccaagggccaggagcgccagcaatgggactggagc
ggcggcgggcgcaagcttaacggcctgggctacccggcgctgcgcggggccaaccagctg
ctcaacgcggcggcggcgctggccgcgctgcaggccatgcgcccgcgcctgccggtcagc
gcacaggaagtgcgcaacgggctggcctttgtcgaactgccgggacgcttccaggtgctg
ccggggcgcccggcggtgatcctggacgtggcgcacaatccgcatgcggcggccacgctg
gggcaaaacctggagaacatggggttcttccgctacacctatgcggtgttcggcgcgatg
caggacaaggacatcgccggggtgctgcagcacgtggccgacaaggtcgaccactggtgc
ctgtgcgacctgccgaccgagcgcgccgccagtgccgcggacctgctggccaagctggag
gcgggcggattccgccccgggccggacgccaccgcggcctgcttttccagccccgaggcg
gcattccgcgatgccatcgagcgagccaccgagaatgatagaattctggtcttcggatcg
ttctataccgtcgccggcgtgatggcctatcgtgccacgcaggctaactga
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