KEGG   Delphinapterus leucas (beluga whale): 111165253
Entry
111165253         CDS       T05885                                 
Symbol
TPH1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle00380  Tryptophan metabolism
dle00790  Folate biosynthesis
dle01100  Metabolic pathways
dle04726  Serotonergic synapse
Module
dle_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:dle00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    111165253 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    111165253 (TPH1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    111165253 (TPH1)
Enzymes [BR:dle01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     111165253 (TPH1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT ACT_4 zf-C2HE SesA DUF5370
Other DBs
NCBI-GeneID: 111165253
NCBI-ProteinID: XP_022411410
UniProt: A0A2Y9LPV6
LinkDB
Position
Unknown
AA seq 455 aa
MIEDNKENKDHSLEKGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRSSEF
EIFVDCDISREQLNDIFHLLKSHTNVLSVNLPDNFTVKEDGMETVPWFPKKISDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPNVEFTEEEIKTWGTVFRE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEEAVQKLATCYFFTVEFGLCKQEGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIRRPFGVKYNPYTRSIQILKDTKSITSA
MDELQHELDVVSDALAKVSRQLSILTAASPNPESI
NT seq 1368 nt   +upstreamnt  +downstreamnt
atgattgaagacaataaggaaaacaaagatcattccttagaaaagggaagagcaactctc
attttttccttaaagaatgaagttggaggacttataaaagcactgaaaatcttccaggag
aagcatgtgaacctgttacatattgagtcccgaaaatcaaagagaagaagctcagagttt
gagatttttgttgattgtgatatcagtagagaacagctgaatgatatttttcatctgttg
aagtctcatactaatgttctctctgtgaatctaccagataattttactgtgaaggaagat
ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccactgtgctaac
agagttctgatgtatggatccgaactggatgctgaccatcctggcttcaaagacaatgtc
tatcgtaaaagacgaaagtattttgcagacttggctatgaactataaacatggagacccc
attcccaacgttgaattcactgaggaggagattaagacctggggaactgtgttccgagag
ctcaacaaactttacccaacccatgcctgcagagagtatctcaaaaacttacctttgctt
tctaaatactgtggataccgggaagataatatcccacaattggaagatgtctcaaacttt
ttaaaagagcgcacaggtttttccatccgtcctgtggctggttacttatcaccaagagat
ttcttatcaggtttagcctttcgagtttttcactgcacacagtatgtgagacacagttca
gatcccctctataccccagagccagatacctgccatgaactcctgggtcacgtccccctt
ttggctgaacccagttttgctcagttctcccaagaaattggcctggcatctcttggagct
tcagaagaggctgttcaaaaactggcaacgtgctacttcttcactgtggagtttggtcta
tgtaaacaagaggggcagctaagagtcttcggtgctggcttactttcttccatcagtgaa
ctcaaacacgcactttctggacatgccaaagtaaagccctttgatcctaagattacctgc
aaacaggagtgtctcatcacaacttttcaggatgtctactttgtatctgaaagctttgaa
gatgcaaaggagaagatgagagaatttaccaaaacaatcaggcgtccatttggagtgaag
tataatccgtatacacggagtattcagatcttgaaggacaccaagagcataaccagtgcc
atggatgagctgcagcatgagcttgatgttgtcagtgatgcccttgctaaagtcagcagg
cagctgagcatcttgacagctgccagtcctaatcccgaaagcatctga

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