Drosophila melanogaster (fruit fly): Dmel_CG14670
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Entry
Dmel_CG14670 CDS
T00030
Symbol
Hcs
Name
(RefSeq) holocarboxylase synthetase, isoform B
KO
K01942
biotin---protein ligase [EC:
6.3.4.9
6.3.4.10
6.3.4.11
6.3.4.15
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00780
Biotin metabolism
dme01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00780 Biotin metabolism
Dmel_CG14670 (Hcs)
Enzymes [BR:
dme01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.9 biotin---[methylmalonyl-CoA-carboxytransferase] ligase
Dmel_CG14670 (Hcs)
6.3.4.10 biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase
Dmel_CG14670 (Hcs)
6.3.4.11 biotin---[methylcrotonoyl-CoA-carboxylase] ligase
Dmel_CG14670 (Hcs)
6.3.4.15 biotin---[biotin carboxyl-carrier protein] ligase
Dmel_CG14670 (Hcs)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BPL_LplA_LipB
BPL_C
BPL_N
Motif
Other DBs
NCBI-GeneID:
40659
NCBI-ProteinID:
NP_001262284
FlyBase:
FBgn0037332
UniProt:
A0A0B4KF92
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Position
3R
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AA seq
993 aa
AA seq
DB search
MLTLYYVSATVLQSWRIQKACSKIAEHLAQPSSIAFYTLQSGSDDGFDPALASSELCCNR
NAAKVTDILWLHANQRGCCLRPLQTLHITPWISFPPAPSLLPFSYAADTLTPASTPTEAD
VPRQQRVSLSAQGEERMQLLLEADIEPLQRPSSEDTSAVRLEDYAVQREGDPQPFELLAK
HLKRQSRISVGLDKDGWKKHMEDLRAVGVLAHQATEFEYQRNRSEGRTKSDPTTHDQRPT
SELLAKAVAVVEPTNKAYLSPARTTEASLKAEAKGTSTKPFPTKSDAKPATLAKSEGTPA
TSKEDSKLTPTKGALKTSELEKLAAVQAAQQQKKEAVQVSPVKAAFLAKPPMLSKHDEPD
KASDQPTKPRKSFEAVKPLNSPPSSRAAPSRPVLQRNKDSLQDAKPLNVLVYSDSASARE
STLATLQQLLERNVYTIYPLMPQQAAQKYWTEQTALLVVCGSVAHGIGQILVDYFLQGGK
VLSLCSDILHFVLPNYRTAEVREHELVQFSYDKWQRVKMMHHIFCYQPSPVKKHFSTDSE
ESTKSHSRKPSMELKDLAGHSHNLDVHVLGTEETWNTPSLMLAKSLQSGGKAVFSQVHLE
MNPSEFESDETKYSILKQNERTRLEIFADLLGKYLDVQVRGGDGVDQPQPGVVYKHAYFL
GRHEAKFELLEKLRLRCSGSDNVIATPNLTMKFCGKDDKPPVANNNVLPILIHSCPDDFS
TVDYFDNLKTEHIGRLVIYAPVVSSSMHLINNLELIHGLAVLPVQQTSGVGRRNNQWLSP
PGCAMFSLQLHLTMDSALSSRLPLLQHLVGTAIVNSLRSHEEYGVLDISIKWPNDIYANG
NQKIGGLVINTTLQGSQAIVNIGSGINLNNSRPTVCINDLIREYNTRVPNNKLPILKYEL
LIAMIFNEIERLLGEVQNGDFDSFYALYYSLWLHSGQSVKICLQKDQEKEAEIVGIDDFG
FLEVKLPTGTIEIVQPDGNSFDMLKGLIIPKYQ
NT seq
2982 nt
NT seq
+upstream
nt +downstream
nt
atgttgaccctgtattacgtgagtgccaccgtcctgcagtcctggcgcattcaaaaggcg
tgctccaagatcgccgagcacctcgcgcagccctcgagcatcgccttctataccctccaa
tcgggcagcgatgacggattcgatcccgccctggccagctcggagttgtgctgcaatcgg
aacgcggccaaggtcacggacatcctgtggctgcacgccaaccagcggggttgctgcctg
cgtccgctgcaaacgctacacatcacgccttggatcagctttccgccggcgcccagtctg
cttcccttctcctatgccgccgacacgttaacgccggcgtccacgcccacggaggcggac
gtcccgcgccaacaacgggtttcgctctctgcccaaggggaggagcggatgcagctgctc
cttgaggccgacatagagccactacagcggcccagctccgaggacacatcagcagtacgg
ctggaagattacgcggtgcaacgggaaggggatccgcagccctttgagcttctggccaag
catctgaagcggcaatcccgcataagcgtcggtctggacaaggatggatggaagaagcac
atggaggacttgcgtgccgtaggtgtgctggcgcaccaggccaccgagttcgagtaccag
aggaatcgctctgagggaagaacgaaatcggatcccaccacacatgatcaacgcccgact
tcggagcttttggccaaggctgtggccgtggtggagcccaccaacaaggcatatctgtct
ccggcaaggacgacagaagcctcgctcaaagccgaggccaagggaacgtcaacaaaacct
tttccgactaaaagcgatgccaaacccgccactcttgccaagagcgagggcacgccagcc
acaagcaaagaggactccaagttaacgccaactaagggtgcattaaagacaagcgaacta
gagaaactagcggctgtccaggcagcgcagcagcagaagaaagaggcagtccaggtctct
cccgtcaaggctgctttcttagctaaaccacctatgctaagtaaacatgatgagcctgat
aaggcatcagatcagccaacgaagcccaggaaatcctttgaggcggtaaagccgttaaat
tctcctccgtcatccagagctgctccctcgcgtcctgtgctgcaacgcaacaaggatagc
ctgcaggacgcaaaaccattgaatgttttggtctactcagacagcgccagtgcgcgggaa
tccacattggccactctgcagcagctgctggagcgcaatgtgtacacgatctatcctctg
atgcctcagcaagcggctcaaaaatactggacggaacagactgcgttgctggtcgtctgc
ggatcggtggcacacggaattgggcagatattggtggactactttctgcagggcggcaag
gtgttaagcctgtgctcggatatactgcactttgtactccccaactatcgcacagcggag
gttcgagagcacgaattggttcagttctcctatgacaagtggcagcgggtcaagatgatg
caccacatcttttgctaccaaccgtcgccggtgaagaagcacttctccactgacagcgag
gagtccaccaagtcgcactctcgcaaaccgtccatggaactgaaggatctggccggtcac
agccacaatttggatgtccatgtgctgggaaccgaggaaacctggaatacgcccagcttg
atgttggccaaaagcctgcagagcggcggaaaggccgtcttctcccaagtgcacttggaa
atgaatcccagcgaatttgaatccgatgagactaagtactccattctaaagcaaaacgag
cgaactcgcctcgagatatttgcggatctcctgggaaagtacttggatgtgcaggtccgc
ggtggagacggtgtcgaccagccgcagcctggagttgtctacaagcacgcatatttccta
ggtcggcacgaggccaagtttgagcttctggagaagctacgtctgcgctgcagcggatcc
gacaacgtgatagcaacgccgaacctgacgatgaagttctgtggcaaggacgataagcct
ccagtggccaacaacaatgtcctgcccatactcatacattcctgtccggatgacttctcc
accgtggattacttcgataatcttaagacggaacacatcggacgactggtcatctatgca
ccggtggtcagcagctccatgcatctcataaacaacctggagctcatccacggcctggct
gtgctccccgtgcagcagacgtccggagtgggtcgcagaaataatcaatggcttagtccg
ccgggctgtgccatgttctcgctgcagctgcacctgaccatggacagcgctttgagctct
cggctgcctctgttgcagcaccttgttggaacggcgattgttaattcgctccgcagtcat
gaagagtacggggtgctggatatttccattaagtggccgaatgacatttatgcaaatgga
aatcagaaaattgggggcctcgtcattaataccacacttcagggatcccaagccatcgtc
aatatcggaagtggaattaatttgaacaattcaagaccaacagtttgcatcaatgacttg
ataagagaatataatacccgtgtcccgaacaacaagttacctatacttaagtacgagcta
cttattgccatgatattcaatgaaatcgaaagacttttgggagaagtacaaaacggagac
tttgatagtttttatgcattatactattcgctatggttacacagcgggcaatctgttaag
atttgcctacaaaaagatcaggaaaaagaggccgaaattgtgggaatcgatgactttgga
tttttggaggtgaaattaccaactggtactatagaaattgtgcagcccgatggaaacagc
tttgatatgttgaagggattgattatacccaagtatcaatag
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