Drosophila melanogaster (fruit fly): Dmel_CG3989
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Entry
Dmel_CG3989 CDS
T00030
Symbol
Paics
Name
(RefSeq) PAICS bifunctional enzyme, isoform A
KO
K01587
phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:
4.1.1.21
6.3.2.6
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00230
Purine metabolism
dme01100
Metabolic pathways
Module
dme_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Dmel_CG3989 (Paics)
Enzymes [BR:
dme01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.21 phosphoribosylaminoimidazole carboxylase
Dmel_CG3989 (Paics)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
Dmel_CG3989 (Paics)
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Gene cluster
GFIT
Motif
Pfam:
SAICAR_synt
AIRC
Motif
Other DBs
NCBI-GeneID:
32228
NCBI-ProteinID:
NP_572826
FlyBase:
FBgn0020513
UniProt:
Q9I7S8
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All DBs
Position
X:complement(12757036..12760617)
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AA seq
429 aa
AA seq
DB search
MSTTTTASIEGYKLGKVIIEGKTKQVYDLPEQPGLCLLLSKDRITAGDGVKAHDLAGKAE
ISNTTNGQVFRLLNEAGIRTAYVKQCGAKAFIARKCQMIPIEWVTRRLATGSFLKRNVGV
PEGYRFSPPKQETFFKDDANHDPQWSEEQIVSAKFELNGLVIGQDEVDIMRRTTLLVFEI
LERAWQTKNCALIDMKVEFGICDDGNIVLADIIDSDSWRLWPAGDKRLMVDKQVYRNLAS
VTASDLDTVKRNFIWVAEQLADIVPKKDHLVVILMGSASDISHSEKIATSCRSLGLNVEL
RVSSAHKGPEETLRIVREYESVMSNLIFVAVAGRSNGLGPVVSGSTNYPVINCPPVKSDN
MQVDVWSSLNLPSGLGCATVLYPEAAALHAATILGLGNFMVWSKLRVKALNNFITLKKAD
KELRGVRNA
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccaccacaacagcatccatagagggctataagctcggcaaggtcatcatcgag
ggcaaaaccaaacaggtgtacgatctgccagagcagccaggactttgcctgctcctcagc
aaggatcgcatcaccgccggcgatggtgtcaaagcacatgatctggccggcaaggcggag
atctccaataccaccaacggtcaggtcttccggctgctcaacgaggcaggcattcgcacc
gcctatgtgaagcagtgcggcgccaaggccttcatcgcccgcaagtgccagatgataccc
attgagtgggtgacccgtcgcctggccaccggttcgttcctcaagcgcaatgtcggcgtg
cccgagggctacaggttctcgccgcccaaacaggagacgttcttcaaggatgatgccaac
cacgatccccagtggagcgaggagcaaattgtctccgccaagttcgagctaaatggcctg
gtgatcggccaagatgaggtggacattatgcgtagaaccacactgctggtcttcgagatt
ctcgagagggcatggcagaccaagaattgcgccctgatcgacatgaaagtggagttcggt
atctgcgacgatggcaacatagttctggccgatatcattgattccgattcgtggcgcttg
tggccagcgggtgacaagcgtttgatggtcgacaagcaggtgtatcgcaatctggcatcg
gtgacggccagcgatttggataccgtaaagaggaacttcatttgggtggccgaacaactg
gctgatattgtgcccaagaaggatcacctggttgtcattctgatgggcagtgcttccgat
atatcgcacagcgagaagatagccaccagctgtcgatccctcggccttaatgtggaactt
cgcgtgagttcggcccacaagggaccggaggaaacgttgcgcattgtccgcgaatatgaa
tcggtgatgagcaacttgatctttgtggccgtcgccgggcgatccaatggactgggtcca
gtcgtttccggcagcaccaactatccggtaatcaattgtccgcccgtcaaatcggacaac
atgcaggtggacgtgtggtccagcttgaatctgccatcggggctgggctgtgccacagtt
ctctatccagaggcagctgctctgcatgcggccaccattctggggctgggcaacttcatg
gtctggtcgaaattgcgtgtcaaggcgctcaacaactttatcactctcaagaaggccgac
aaggagttgcgcggcgtgcgaaatgcttag
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