Drosophila melanogaster (fruit fly): Dmel_CG7010
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Entry
Dmel_CG7010 CDS
T00030
Symbol
Pdha
Name
(RefSeq) pyruvate dehydrogenase E1 alpha subunit, isoform A
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00010
Glycolysis / Gluconeogenesis
dme00020
Citrate cycle (TCA cycle)
dme00620
Pyruvate metabolism
dme00785
Lipoic acid metabolism
dme01100
Metabolic pathways
dme01200
Carbon metabolism
dme01210
2-Oxocarboxylic acid metabolism
Module
dme_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Dmel_CG7010 (Pdha)
00020 Citrate cycle (TCA cycle)
Dmel_CG7010 (Pdha)
00620 Pyruvate metabolism
Dmel_CG7010 (Pdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Dmel_CG7010 (Pdha)
Enzymes [BR:
dme01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Dmel_CG7010 (Pdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
31406
NCBI-ProteinID:
NP_572181
FlyBase:
FBgn0028325
UniProt:
Q9W4H6
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Position
X:4702284..4705265
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AA seq
399 aa
AA seq
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MLRTLSRVSELPIIVKQLQKNAAQAGVSKTNNYATEATVQVNRPFKLHRLDEGPATEVKL
TKDQALKYYTQMQTIRRLETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIIS
AYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAG
VGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERA
SCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDP
GTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDA
ELGVSHLWTDVYSNNLEPKLRGTIAYDIDHIQERKGVNH
NT seq
1200 nt
NT seq
+upstream
nt +downstream
nt
atgttgcgtactctgtcacgcgttagcgaattgcccattattgttaagcaactgcaaaaa
aatgcagcccaagcaggtgtttcgaaaaccaacaattatgccacggaggccaccgttcaa
gtgaatcggcccttcaagctgcaccgcctggacgaaggacccgccacggaagtgaagctg
accaaggatcaggccctcaagtactacacacagatgcagacgatccgtcggttggagacg
gccgccggtaatctgtacaaggagaagatcattcgcggcttctgtcatctgtattccggc
caggaggcatgcgccgttggcatgaaggcggcgatgcgggatgtggacaacatcatctcg
gcgtaccgtgtccacggatggacctacctgatgggcgtctcacccagcggcgtactggct
gagctcaccggtgtccagggtggctgtgcccgcggcaagggtggctccatgcacatgtac
gcaccgaacttctacggaggcaatggcatcgtgggtgctcaagttcctttgggtgccggc
gttggcttggcctgcaagtacaagggcaatggcggcatgtgcctggccctctacggtgat
ggtgccgccaatcaaggacaggtgttcgaggcttacaacatggcctacctgtggaaactg
cctgtgatctttgtctgcgagaacaacaactacggaatgggcaccagttctgagcgtgct
tcctgcaacactgattactatacccgcggcgacgctctgcccggaatctgggtggacggc
atggatgtgctggccgtgcgcagcgccaccgagttcgccatcaactatgtgaacactcac
ggacctttggtgatggagacgaacacgtaccgatactctggacactccatgtccgatccg
ggcacatcgtaccgcacacgcgaggagatccaggaggtgcgccagaagcgtgatcccatc
acctccttcaaggagctgtgcatcgagctgggtctgattaccaccgatgaagttaaggcc
atcgatctgaaggtacgcaaggaggtcgacgaggccaccgccttcgccaagtccgatgcc
gagctgggcgtgagccacctctggacggacgtgtactccaacaatctggagcccaagctg
cgcggcaccatcgcctacgatattgatcacatccaggagcgcaagggcgtcaatcactaa
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